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The map label for this gene is appB [H]

Identifier: 125624267

GI number: 125624267

Start: 1431074

End: 1432054

Strand: Reverse

Name: appB [H]

Synonym: llmg_1459

Alternate gene names: 125624267

Gene position: 1432054-1431074 (Counterclockwise)

Preceding gene: 125624268

Following gene: 125624266

Centisome position: 56.61

GC content: 38.12

Gene sequence:

>981_bases
ATGAGATTCTTTATTCGAAGAGTGGCTTTCTATATTGTAACAGCCTGGGCCGCTGTCACCTTAAACTTTTTTATTCCGAG
AATGATGCCGGGCGACCCAGTTCAAGCTTTAATTGCACGATATCAAGGACAAATATCAGTTGATGCAGTAAATTCACTAC
GTAAATTATTTGGAATGGATGCTCATGAAAGTCTGTGGCAACAATATATTGATTATTGGGTCAAACTTTTTCATGGCAAC
TTAGGTGTATCTTTGCAGTCATTCCCTACTCCAGTATCACAAATTATTAGCCAATCTCTACCATGGACCATCGGTTTAGT
CGGTTTGGCTACAATTATTGCTTTTGTAGTGGGGACAGTCATTGGGATTATTCTTGGTTGGCGTCGTGGAACAAAATGGG
ATGCTTTAATTCCAATTACAACTTTTTTCTCTTCAGTTCCCTATTTTTGGATTGGTTTGATGGCAATTGCTATTTTTGCA
ACTGTTCTTCAATGGTTTCCTCAAGGTGGCTCCTATTCAGTTGATAGTTTGCCAGGTTTAAATTGGGCTTTTATGTCTTC
GGTATTCTATTATGGATTTTTACCTGCTTTAACTATTGTATTAAGTTCGATGGCAGGTTGGATTTTAGGAATGCGCAATA
TGATGGTTACTGTTTCTTCGGAAGATTACGTGACTGTTGCCCATGCAAAGGGATTGAGAGAATCAGTCGTCATGTTTCGT
TACGCCTCACGTAATGCTATTTTGCCACAAATTTCTGGTTTTGCTTTATCTCTAGGCTTTGTTGTTTCAGGGACTTTGGT
TATGGAGCAAGTTTTTAATTACCAAGGAATAGGTTATCGCTTATTACAAGCAACAAATAATCATGATTACCCGCTGATGC
AAGGTATTTTCCTAGTTATTACCTTATCAGTATTGATTGCTAATGTTGTCGCAGACATAATTTATGCATTTCTTGATCCA
CGTACACGAAAGGAGGGTTAA

Upstream 100 bases:

>100_bases
TGGTGAATATCGGAAATAAAGGAGATTTAACTACAATTCATGATTTGAACTTACCAGAACAAGTCAAAGCTAAGCTCATT
CAAAATAAGGAGGAAAAATA

Downstream 100 bases:

>100_bases
AATGGCTGAAATAACGACAGATCATAAAGCAAATGAATTAAAAGAACCAGAAAAGATTGAGCTTGAAAAGAAACAGCATA
TGGTTTTTTTACGTAATACA

Product: putative di/Tri-peptide transport system permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MRFFIRRVAFYIVTAWAAVTLNFFIPRMMPGDPVQALIARYQGQISVDAVNSLRKLFGMDAHESLWQQYIDYWVKLFHGN
LGVSLQSFPTPVSQIISQSLPWTIGLVGLATIIAFVVGTVIGIILGWRRGTKWDALIPITTFFSSVPYFWIGLMAIAIFA
TVLQWFPQGGSYSVDSLPGLNWAFMSSVFYYGFLPALTIVLSSMAGWILGMRNMMVTVSSEDYVTVAHAKGLRESVVMFR
YASRNAILPQISGFALSLGFVVSGTLVMEQVFNYQGIGYRLLQATNNHDYPLMQGIFLVITLSVLIANVVADIIYAFLDP
RTRKEG

Sequences:

>Translated_326_residues
MRFFIRRVAFYIVTAWAAVTLNFFIPRMMPGDPVQALIARYQGQISVDAVNSLRKLFGMDAHESLWQQYIDYWVKLFHGN
LGVSLQSFPTPVSQIISQSLPWTIGLVGLATIIAFVVGTVIGIILGWRRGTKWDALIPITTFFSSVPYFWIGLMAIAIFA
TVLQWFPQGGSYSVDSLPGLNWAFMSSVFYYGFLPALTIVLSSMAGWILGMRNMMVTVSSEDYVTVAHAKGLRESVVMFR
YASRNAILPQISGFALSLGFVVSGTLVMEQVFNYQGIGYRLLQATNNHDYPLMQGIFLVITLSVLIANVVADIIYAFLDP
RTRKEG
>Mature_326_residues
MRFFIRRVAFYIVTAWAAVTLNFFIPRMMPGDPVQALIARYQGQISVDAVNSLRKLFGMDAHESLWQQYIDYWVKLFHGN
LGVSLQSFPTPVSQIISQSLPWTIGLVGLATIIAFVVGTVIGIILGWRRGTKWDALIPITTFFSSVPYFWIGLMAIAIFA
TVLQWFPQGGSYSVDSLPGLNWAFMSSVFYYGFLPALTIVLSSMAGWILGMRNMMVTVSSEDYVTVAHAKGLRESVVMFR
YASRNAILPQISGFALSLGFVVSGTLVMEQVFNYQGIGYRLLQATNNHDYPLMQGIFLVITLSVLIANVVADIIYAFLDP
RTRKEG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=343, Percent_Identity=29.7376093294461, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1787053, Length=326, Percent_Identity=30.0613496932515, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789888, Length=326, Percent_Identity=27.9141104294479, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787497, Length=324, Percent_Identity=24.3827160493827, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788504, Length=370, Percent_Identity=28.9189189189189, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1787761, Length=339, Percent_Identity=29.7935103244838, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787550, Length=279, Percent_Identity=27.2401433691756, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36422; Mature: 36422

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFFIRRVAFYIVTAWAAVTLNFFIPRMMPGDPVQALIARYQGQISVDAVNSLRKLFGMD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCC
AHESLWQQYIDYWVKLFHGNLGVSLQSFPTPVSQIISQSLPWTIGLVGLATIIAFVVGTV
HHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IGIILGWRRGTKWDALIPITTFFSSVPYFWIGLMAIAIFATVLQWFPQGGSYSVDSLPGL
HHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NWAFMSSVFYYGFLPALTIVLSSMAGWILGMRNMMVTVSSEDYVTVAHAKGLRESVVMFR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEHHHHHHHHHHHHHH
YASRNAILPQISGFALSLGFVVSGTLVMEQVFNYQGIGYRLLQATNNHDYPLMQGIFLVI
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHH
TLSVLIANVVADIIYAFLDPRTRKEG
HHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRFFIRRVAFYIVTAWAAVTLNFFIPRMMPGDPVQALIARYQGQISVDAVNSLRKLFGMD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCC
AHESLWQQYIDYWVKLFHGNLGVSLQSFPTPVSQIISQSLPWTIGLVGLATIIAFVVGTV
HHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IGIILGWRRGTKWDALIPITTFFSSVPYFWIGLMAIAIFATVLQWFPQGGSYSVDSLPGL
HHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NWAFMSSVFYYGFLPALTIVLSSMAGWILGMRNMMVTVSSEDYVTVAHAKGLRESVVMFR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEHHHHHHHHHHHHHH
YASRNAILPQISGFALSLGFVVSGTLVMEQVFNYQGIGYRLLQATNNHDYPLMQGIFLVI
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHH
TLSVLIANVVADIIYAFLDPRTRKEG
HHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]