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The map label for this gene is bglA2 [H]

Identifier: 125624263

GI number: 125624263

Start: 1425329

End: 1426771

Strand: Reverse

Name: bglA2 [H]

Synonym: llmg_1455

Alternate gene names: 125624263

Gene position: 1426771-1425329 (Counterclockwise)

Preceding gene: 125624264

Following gene: 125624262

Centisome position: 56.41

GC content: 33.75

Gene sequence:

>1443_bases
ATGAGTTTAATAAAAAAATTTCCTGAAGAATTTCTTTGGGGAGGAGCCGTAGCTGCTCACCAAATTGAGGGTGCTTTCAA
TGAAGGAGGACGAGGTTTATCCTGTGCAGATGTACTAACTGCAGGTAGTAATGGGGTGGAAAGAGAAATTACAGATGGAA
TAATTCAGGGGAAATATTATCCAAATCATGAAGCTATTGATTTTTATCATCGTTATAAAGAAGACATCAAACTTTTTCGT
GAATTAGGACTTAAAACTTTTCGTACCTCAATTTCTTGGAGTCGTATTTTTCCAAATGGAGATGAAAAAATCCCAAATGA
AAAAGGTTTGATATTTTACGATGAGCTTTTTGATGAACTCCTTTTAAATGGTATAGAGCCGGTAATTACCTTATCACATT
TTGAAATACCTTACCATCTGTATACAGAGTATGGAGGTTTTAGAAATAAAAAAATGATTGATTTTTTTGTCAACTATGCC
GAGGTCGTTTTAAAACGTTATAAAAATAAGGTAAAATACTGGATGACTTTTAATGAAATTAATAATCAAGCAGATGGTCA
ATCTTCCTTGCATGTTTGGACAAATTCAGCTATTCGCTTAAAAGATGATGACATCAAAGAAGAGGTTGTCTTTCAAGCGT
CTCTAAATGAACTAATTGCTTCGGCCAAAGTCGTAAAATTAGCTCATGAAATTAATCCTAATTTTCAAATAGGATGTATG
ATGGCTTATGTTCCTGTTTATGCCTATTCTTGCAATCCAACAGATGCGATGGCAGCAATAAAAGTTATGGAACGTCGTTA
CTTTTATAGTGATATTCATGTGCGAGGGCATATTCCAAAATATACCCTTAACTATTGGCATAAAAAACATTATCATATTG
ATTATTCAGTTGATGAACTGAAAATTTTAACTGAGGGGACAGTTGATTTTATTGGTTTTTCTTACTATATGTCGAGTTCT
GAGACGACAGTTGACGAGTTATCCGGTCAACCAATTCCTGATTTTCCTCATGCAAAAATAACATCAAATCCTTACATTAA
GACAAGTGACTGGGGATGGCAAATAGATCCAGTTGGTTTGCGTTATGTGCTAAATATGGTCTATGAACGTTATGAAAAGC
CAATATTTATTGTTGAAAATGGTTTTGGTGCTTATGATAAAATTGAAAATGATGGAAGTATTCATGATCAATATCGTATA
GATTATCTTAGAGCACATATTGAGCAAATGGAAAAAGCAATTAATGAGGATGGTGTTGATTTAATTGGATATACTCCATG
GGGAATTATTGATTTGGTTAGATTTGGTTCTGGAGAAATGGAAAAACGATACGGTATGATCTATGTTGATAAAGATAATC
AGGGGCGGGGTTCACTAAAGCGCAGTAAAAAAGATTCTTTTTCTTGGTATCATGATGTCATAGAGAATAATGGATTGGAG
TAG

Upstream 100 bases:

>100_bases
AAAAAGTTTTCGAAAATGGAACAATAAATTTTTATATCAATGATTTGAATAAAAAAGTAGCTAATGTTGAAGTCCAAAAT
AGAAGGGAGGGAATTTATAA

Downstream 100 bases:

>100_bases
AGATGAGTAAATATATAGCCTTTGATATTGGTGGAACTTTTATCAAATATGGAGTTGTTGACGACTCAGGAAAAATACTA
AAAAAAGGAAAAATTTCAAC

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MSLIKKFPEEFLWGGAVAAHQIEGAFNEGGRGLSCADVLTAGSNGVEREITDGIIQGKYYPNHEAIDFYHRYKEDIKLFR
ELGLKTFRTSISWSRIFPNGDEKIPNEKGLIFYDELFDELLLNGIEPVITLSHFEIPYHLYTEYGGFRNKKMIDFFVNYA
EVVLKRYKNKVKYWMTFNEINNQADGQSSLHVWTNSAIRLKDDDIKEEVVFQASLNELIASAKVVKLAHEINPNFQIGCM
MAYVPVYAYSCNPTDAMAAIKVMERRYFYSDIHVRGHIPKYTLNYWHKKHYHIDYSVDELKILTEGTVDFIGFSYYMSSS
ETTVDELSGQPIPDFPHAKITSNPYIKTSDWGWQIDPVGLRYVLNMVYERYEKPIFIVENGFGAYDKIENDGSIHDQYRI
DYLRAHIEQMEKAINEDGVDLIGYTPWGIIDLVRFGSGEMEKRYGMIYVDKDNQGRGSLKRSKKDSFSWYHDVIENNGLE

Sequences:

>Translated_480_residues
MSLIKKFPEEFLWGGAVAAHQIEGAFNEGGRGLSCADVLTAGSNGVEREITDGIIQGKYYPNHEAIDFYHRYKEDIKLFR
ELGLKTFRTSISWSRIFPNGDEKIPNEKGLIFYDELFDELLLNGIEPVITLSHFEIPYHLYTEYGGFRNKKMIDFFVNYA
EVVLKRYKNKVKYWMTFNEINNQADGQSSLHVWTNSAIRLKDDDIKEEVVFQASLNELIASAKVVKLAHEINPNFQIGCM
MAYVPVYAYSCNPTDAMAAIKVMERRYFYSDIHVRGHIPKYTLNYWHKKHYHIDYSVDELKILTEGTVDFIGFSYYMSSS
ETTVDELSGQPIPDFPHAKITSNPYIKTSDWGWQIDPVGLRYVLNMVYERYEKPIFIVENGFGAYDKIENDGSIHDQYRI
DYLRAHIEQMEKAINEDGVDLIGYTPWGIIDLVRFGSGEMEKRYGMIYVDKDNQGRGSLKRSKKDSFSWYHDVIENNGLE
>Mature_479_residues
SLIKKFPEEFLWGGAVAAHQIEGAFNEGGRGLSCADVLTAGSNGVEREITDGIIQGKYYPNHEAIDFYHRYKEDIKLFRE
LGLKTFRTSISWSRIFPNGDEKIPNEKGLIFYDELFDELLLNGIEPVITLSHFEIPYHLYTEYGGFRNKKMIDFFVNYAE
VVLKRYKNKVKYWMTFNEINNQADGQSSLHVWTNSAIRLKDDDIKEEVVFQASLNELIASAKVVKLAHEINPNFQIGCMM
AYVPVYAYSCNPTDAMAAIKVMERRYFYSDIHVRGHIPKYTLNYWHKKHYHIDYSVDELKILTEGTVDFIGFSYYMSSSE
TTVDELSGQPIPDFPHAKITSNPYIKTSDWGWQIDPVGLRYVLNMVYERYEKPIFIVENGFGAYDKIENDGSIHDQYRID
YLRAHIEQMEKAINEDGVDLIGYTPWGIIDLVRFGSGEMEKRYGMIYVDKDNQGRGSLKRSKKDSFSWYHDVIENNGLE

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=499, Percent_Identity=29.4589178356713, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI13273313, Length=496, Percent_Identity=27.6209677419355, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI32481206, Length=494, Percent_Identity=27.5303643724696, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI24497614, Length=491, Percent_Identity=28.9205702647658, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI28376633, Length=491, Percent_Identity=25.8655804480652, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI2367174, Length=478, Percent_Identity=57.1129707112971, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1789070, Length=482, Percent_Identity=46.4730290456432, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI2367270, Length=476, Percent_Identity=46.6386554621849, Blast_Score=430, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17552856, Length=496, Percent_Identity=30.241935483871, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17539390, Length=491, Percent_Identity=30.142566191446, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21356577, Length=504, Percent_Identity=26.5873015873016, Blast_Score=147, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55655; Mature: 55523

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIKKFPEEFLWGGAVAAHQIEGAFNEGGRGLSCADVLTAGSNGVEREITDGIIQGKYY
CCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHEECCCC
PNHEAIDFYHRYKEDIKLFRELGLKTFRTSISWSRIFPNGDEKIPNEKGLIFYDELFDEL
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCEEECCCCCCCCCCCCCCEEEHHHHHHHH
LLNGIEPVITLSHFEIPYHLYTEYGGFRNKKMIDFFVNYAEVVLKRYKNKVKYWMTFNEI
HHCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEHHH
NNQADGQSSLHVWTNSAIRLKDDDIKEEVVFQASLNELIASAKVVKLAHEINPNFQIGCM
CCCCCCCCCEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHE
MAYVPVYAYSCNPTDAMAAIKVMERRYFYSDIHVRGHIPKYTLNYWHKKHYHIDYSVDEL
EEEEEHEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHCCEEEEEECCHHHE
KILTEGTVDFIGFSYYMSSSETTVDELSGQPIPDFPHAKITSNPYIKTSDWGWQIDPVGL
EEEECCCHHHEEEEEEECCCCCCHHHCCCCCCCCCCCCEECCCCCEEECCCCEEECCHHH
RYVLNMVYERYEKPIFIVENGFGAYDKIENDGSIHDQYRIDYLRAHIEQMEKAINEDGVD
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
LIGYTPWGIIDLVRFGSGEMEKRYGMIYVDKDNQGRGSLKRSKKDSFSWYHDVIENNGLE
EEEECCHHHHHHHHCCCCCHHHHCCEEEEECCCCCCCCHHHCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLIKKFPEEFLWGGAVAAHQIEGAFNEGGRGLSCADVLTAGSNGVEREITDGIIQGKYY
CHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHEECCCC
PNHEAIDFYHRYKEDIKLFRELGLKTFRTSISWSRIFPNGDEKIPNEKGLIFYDELFDEL
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCEEECCCCCCCCCCCCCCEEEHHHHHHHH
LLNGIEPVITLSHFEIPYHLYTEYGGFRNKKMIDFFVNYAEVVLKRYKNKVKYWMTFNEI
HHCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEHHH
NNQADGQSSLHVWTNSAIRLKDDDIKEEVVFQASLNELIASAKVVKLAHEINPNFQIGCM
CCCCCCCCCEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHE
MAYVPVYAYSCNPTDAMAAIKVMERRYFYSDIHVRGHIPKYTLNYWHKKHYHIDYSVDEL
EEEEEHEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHCCEEEEEECCHHHE
KILTEGTVDFIGFSYYMSSSETTVDELSGQPIPDFPHAKITSNPYIKTSDWGWQIDPVGL
EEEECCCHHHEEEEEEECCCCCCHHHCCCCCCCCCCCCEECCCCCEEECCCCEEECCHHH
RYVLNMVYERYEKPIFIVENGFGAYDKIENDGSIHDQYRIDYLRAHIEQMEKAINEDGVD
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
LIGYTPWGIIDLVRFGSGEMEKRYGMIYVDKDNQGRGSLKRSKKDSFSWYHDVIENNGLE
EEEECCHHHHHHHHCCCCCHHHHCCEEEEECCCCCCCCHHHCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]