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The map label for this gene is nanE

Identifier: 125624137

GI number: 125624137

Start: 1288947

End: 1289651

Strand: Direct

Name: nanE

Synonym: llmg_1317

Alternate gene names: 125624137

Gene position: 1288947-1289651 (Clockwise)

Preceding gene: 125624109

Following gene: 125624139

Centisome position: 50.96

GC content: 36.17

Gene sequence:

>705_bases
ATGAATAAAGAACAATTTTTAGAAAAAATAAAGGGTGGAATAATCGTATCTTGTCAAGCCTTACCCGGTGAACCATTATA
TTCTGAAAATGGAGGAGTTATGCCTTTGATGGCAAAAGCTGCTGAACAAGCTGGAGCTGTCGCTATCAGAGCAAACTCGG
TCAGAGATATAAAAGAAATTCAAAAAGCGGTAAGTTTACCCATCATAGGTATTATTAAAAAAGATTATTTGCCTCAAAAG
CCCTTCATTACAGCGACTATGAAAGAGATTGATGAATTAGTTGCTACTTCTTGTGAGGTAATAGCCTTAGATTGTACTCT
GAGAGAACGTCATGATGGGCTAACTATTAATCAATTTATCAAAAAAATCAAAGAAAAATATCCAACTCAAATTTTAATGG
CTGACTGCTCAAATTTTAAAGAGTGTGAAAATGCTTATTCTGCTGGAGTAGACTTTGTTGGAACTACTCTCAGTGGCTAT
ACAGAAGAAAGTAAAAAACAAGATGGACCTGACTTTGAATTACTTGAAAAGTTAGTTGAGGCAAAAATTCCCGTTATCGC
TGAAGGAAGGATTCACAGTCCCGAACAGGCACAGTATGTCCAAAAAATTGGAGTAGACGGAATGGTTATTGGTGGTGCAA
TTACTAGACCTCTTGAAATCGCGTCTCGTTTTGTTCAAGCAGTTGAATCAGTTGAAAAACTATAA

Upstream 100 bases:

>100_bases
CTTAAATTTATTTTATCATAATTGACAAAAATGTAAGCGTATGCTATATTAATTATGGAGTAATTATCCAAAAACAGATT
TTATGGAGGGTAAATGGAGA

Downstream 100 bases:

>100_bases
TCACTTATCTATAAAATCATTAAAGCAAGAATATAAAATTAGAGTAAATAAAAAAACATTATCTAACTGATAATGTTTTT
GCATTTATTTCTCGTTTGTA

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNKEQFLEKIKGGIIVSCQALPGEPLYSENGGVMPLMAKAAEQAGAVAIRANSVRDIKEIQKAVSLPIIGIIKKDYLPQK
PFITATMKEIDELVATSCEVIALDCTLRERHDGLTINQFIKKIKEKYPTQILMADCSNFKECENAYSAGVDFVGTTLSGY
TEESKKQDGPDFELLEKLVEAKIPVIAEGRIHSPEQAQYVQKIGVDGMVIGGAITRPLEIASRFVQAVESVEKL

Sequences:

>Translated_234_residues
MNKEQFLEKIKGGIIVSCQALPGEPLYSENGGVMPLMAKAAEQAGAVAIRANSVRDIKEIQKAVSLPIIGIIKKDYLPQK
PFITATMKEIDELVATSCEVIALDCTLRERHDGLTINQFIKKIKEKYPTQILMADCSNFKECENAYSAGVDFVGTTLSGY
TEESKKQDGPDFELLEKLVEAKIPVIAEGRIHSPEQAQYVQKIGVDGMVIGGAITRPLEIASRFVQAVESVEKL
>Mature_234_residues
MNKEQFLEKIKGGIIVSCQALPGEPLYSENGGVMPLMAKAAEQAGAVAIRANSVRDIKEIQKAVSLPIIGIIKKDYLPQK
PFITATMKEIDELVATSCEVIALDCTLRERHDGLTINQFIKKIKEKYPTQILMADCSNFKECENAYSAGVDFVGTTLSGY
TEESKKQDGPDFELLEKLVEAKIPVIAEGRIHSPEQAQYVQKIGVDGMVIGGAITRPLEIASRFVQAVESVEKL

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential)

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family

Homologues:

Organism=Escherichia coli, GI1789617, Length=227, Percent_Identity=36.5638766519824, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NANE_LACLM (A2RKU2)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001032620.1
- ProteinModelPortal:   A2RKU2
- SMR:   A2RKU2
- STRING:   A2RKU2
- GeneID:   4797484
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_1317
- eggNOG:   COG3010
- HOGENOM:   HBG296941
- OMA:   ITRPMEI
- ProtClustDB:   PRK01130
- HAMAP:   MF_01235
- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF04131 NanE; SSF51366 RibP_bind_barrel

EC number: =5.1.3.9

Molecular weight: Translated: 25644; Mature: 25644

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEQFLEKIKGGIIVSCQALPGEPLYSENGGVMPLMAKAAEQAGAVAIRANSVRDIKEI
CCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHH
QKAVSLPIIGIIKKDYLPQKPFITATMKEIDELVATSCEVIALDCTLRERHDGLTINQFI
HHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCHHHHH
KKIKEKYPTQILMADCSNFKECENAYSAGVDFVGTTLSGYTEESKKQDGPDFELLEKLVE
HHHHHHCCHHEEHHHHCCHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCCCCHHHHHHHHH
AKIPVIAEGRIHSPEQAQYVQKIGVDGMVIGGAITRPLEIASRFVQAVESVEKL
CCCCEEECCCCCCCHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKEQFLEKIKGGIIVSCQALPGEPLYSENGGVMPLMAKAAEQAGAVAIRANSVRDIKEI
CCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHH
QKAVSLPIIGIIKKDYLPQKPFITATMKEIDELVATSCEVIALDCTLRERHDGLTINQFI
HHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCHHHHH
KKIKEKYPTQILMADCSNFKECENAYSAGVDFVGTTLSGYTEESKKQDGPDFELLEKLVE
HHHHHHCCHHEEHHHHCCHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCCCCHHHHHHHHH
AKIPVIAEGRIHSPEQAQYVQKIGVDGMVIGGAITRPLEIASRFVQAVESVEKL
CCCCEEECCCCCCCHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA