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The map label for this gene is arsR [C]

Identifier: 124485643

GI number: 124485643

Start: 798328

End: 798774

Strand: Reverse

Name: arsR [C]

Synonym: Mlab_0821

Alternate gene names: 124485643

Gene position: 798774-798328 (Counterclockwise)

Preceding gene: 124485644

Following gene: 124485642

Centisome position: 44.25

GC content: 52.57

Gene sequence:

>447_bases
ATGACGAGGTCAGACAGATCCTCCACGTTTCCGACAGCCTTATCGAACGAAAAACGCATTGCGGCTGCTGCTGCATTCCC
GGATACGAATGCGATGAGTGATCCGGAAACGATCTTCAAAGCCTGCGGCGACACGACCAGACTTCGGATCCTTGCCCTTC
TGCAGGGTAATGAGTTATGCGTCTGCGAGATCGAAGCGGCGCTTTCCCTCTCCCAGCCAAACGCCTCGCGCAGTCTGACG
ATCCTGAAAAACGCCGGCATCATTCAGAGCAGAAAACAGGCGCAATGGACCTACTACAAAATCAGCGATGATTTTGCCGC
CGCATTCCCGGATCTTTCCAAAGCCCTGGAAAAGATCTGCGCCGGTCTCCCGACAACAAACGCCGACAAAGCCCTCTTAC
AAAAACTCAGAGAAATGCACTCAAGTACACCATGTGATGAATCATGA

Upstream 100 bases:

>100_bases
AACCCAAATGTTGCCCGTCTCATATCCCTGAACGGGGAAAAGCTCCTTCCGGCCGTCGTCGTCAACAACTTTGTGATGAT
CACCGGCAGGTATCCAACCG

Downstream 100 bases:

>100_bases
CCGAAGAAAAAAAGACCTCGATATTTGGAAAGATGAAGAAAGCGATCACCGCAGAAAACTGTTCCTGCTGCTGTAATATC
AAAATCGTGCCGGAAAAGCC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MTRSDRSSTFPTALSNEKRIAAAAAFPDTNAMSDPETIFKACGDTTRLRILALLQGNELCVCEIEAALSLSQPNASRSLT
ILKNAGIIQSRKQAQWTYYKISDDFAAAFPDLSKALEKICAGLPTTNADKALLQKLREMHSSTPCDES

Sequences:

>Translated_148_residues
MTRSDRSSTFPTALSNEKRIAAAAAFPDTNAMSDPETIFKACGDTTRLRILALLQGNELCVCEIEAALSLSQPNASRSLT
ILKNAGIIQSRKQAQWTYYKISDDFAAAFPDLSKALEKICAGLPTTNADKALLQKLREMHSSTPCDES
>Mature_147_residues
TRSDRSSTFPTALSNEKRIAAAAAFPDTNAMSDPETIFKACGDTTRLRILALLQGNELCVCEIEAALSLSQPNASRSLTI
LKNAGIIQSRKQAQWTYYKISDDFAAAFPDLSKALEKICAGLPTTNADKALLQKLREMHSSTPCDES

Specific function: Transcriptional Repressor For The Arsefg Operon. Arse Is A Trans-Acting Regulatory Protein Which Controls Its Own Expression. The Repressive Effect Of Arse Is Alleviated By Oxyions Of +III Oxidation State Of Arsenic, Antimony, And Bismuth, As Well As Arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=74, Percent_Identity=43.2432432432432, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 16086; Mature: 15955

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSDRSSTFPTALSNEKRIAAAAAFPDTNAMSDPETIFKACGDTTRLRILALLQGNELC
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCHHEEEEEEECCCCEE
VCEIEAALSLSQPNASRSLTILKNAGIIQSRKQAQWTYYKISDDFAAAFPDLSKALEKIC
EEEEHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCHHHHCHHHHHHHHHHH
AGLPTTNADKALLQKLREMHSSTPCDES
CCCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TRSDRSSTFPTALSNEKRIAAAAAFPDTNAMSDPETIFKACGDTTRLRILALLQGNELC
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCHHEEEEEEECCCCEE
VCEIEAALSLSQPNASRSLTILKNAGIIQSRKQAQWTYYKISDDFAAAFPDLSKALEKIC
EEEEHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCHHHHCHHHHHHHHHHH
AGLPTTNADKALLQKLREMHSSTPCDES
CCCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]