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The map label for this gene is gsiC [H]

Identifier: 124485542

GI number: 124485542

Start: 692605

End: 693555

Strand: Reverse

Name: gsiC [H]

Synonym: Mlab_0719

Alternate gene names: 124485542

Gene position: 693555-692605 (Counterclockwise)

Preceding gene: 124485543

Following gene: 124485541

Centisome position: 38.42

GC content: 52.37

Gene sequence:

>951_bases
ATGCTGAGAGAGTATTTCATCAGAAGACTTCTGTATCTGATACCGATACTTATCTTCATCTCATTTTTGAGTTTTTCTCT
TATCTACATCGCCCCGGGAGACCCGGCGGAGATCATGATGACGAGCCCCGGCGGGGGCTACGATGAGGCGGCCGTCGAAC
AATTCCGTGTGGCCCACGGACTTGACCAGCCGTTCATCGTCCAGTATATGACCTGGCTGAAAAACGCAGCGACCGGCGAT
CTTGGGTACTCCTACATGAGCGAACAACCCGTCTTTGAGACCGTGATCAATGCATTCAAAAATACACTGACTCTGTCGGC
CCTTGCACTCGTCATCGCACTTATCATCGCGATCCCGCTTGGCATCATCTCGGCGGTCAAACACAACACGATCTTCGACA
GTTTATGCCGGTTCGGCGCCCTTATCGGCGTGTCGATGCCGAACTTCTGGCAGGCATACCTTATGATCATCGTGTTTTCC
GTCATCCTTCACTGGCTGCCGGGCGGCGGGTTCGGGCACGGGACCGACATCTCGTATATGATCCTCCCCGCCCTTGTCCT
TGGGACGGGATCGGCCGCCGTGATGATGCGCATGGTCAGATCGAGTATGCTCGATGTGCTTGGAAAAGAGTATATCCAGA
CTGCCCGGGCAAAGGGTTTGTCCGAGGCGACGGTTTTGATGCGGCATGCGCTGAAAAACGCCCTTGTTCCGATCATTACC
GTTGTCGGTCTTTCGATCGGATTCCTCTTAAACGGGTCCGTCGTGGTAGAAACGATCTTCGGCTGGCCGGGTATCGGAAA
TCTCGTCGTAAGTTCGATTCTCTCGTATGATTACATGATGATCCAGGGTTCCATCCTCTTCGTCGCAATCATATTTTTAG
TCATCAACTTCATTGTCGACCTGCTCTATGTATGGGCAAACCCGGAGATACGATATGACAGAACTTCGTAA

Upstream 100 bases:

>100_bases
ACTCGACATGGCGGTATCTTGACGACTATCAGGCGTTCCTGAAGTCGATCGATATCGGCGAAACTACGGTCACCCCCTAC
ATAGTCTCTGCAAAGAAATC

Downstream 100 bases:

>100_bases
GTATCTCAAAAACCGGCAGATCATGATCTCCCTCATCATTCTTGGGCTGCTCATCTGTATGGCGCTTTTTGCGGATGTTC
TGTCACCGTACGACTACACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLREYFIRRLLYLIPILIFISFLSFSLIYIAPGDPAEIMMTSPGGGYDEAAVEQFRVAHGLDQPFIVQYMTWLKNAATGD
LGYSYMSEQPVFETVINAFKNTLTLSALALVIALIIAIPLGIISAVKHNTIFDSLCRFGALIGVSMPNFWQAYLMIIVFS
VILHWLPGGGFGHGTDISYMILPALVLGTGSAAVMMRMVRSSMLDVLGKEYIQTARAKGLSEATVLMRHALKNALVPIIT
VVGLSIGFLLNGSVVVETIFGWPGIGNLVVSSILSYDYMMIQGSILFVAIIFLVINFIVDLLYVWANPEIRYDRTS

Sequences:

>Translated_316_residues
MLREYFIRRLLYLIPILIFISFLSFSLIYIAPGDPAEIMMTSPGGGYDEAAVEQFRVAHGLDQPFIVQYMTWLKNAATGD
LGYSYMSEQPVFETVINAFKNTLTLSALALVIALIIAIPLGIISAVKHNTIFDSLCRFGALIGVSMPNFWQAYLMIIVFS
VILHWLPGGGFGHGTDISYMILPALVLGTGSAAVMMRMVRSSMLDVLGKEYIQTARAKGLSEATVLMRHALKNALVPIIT
VVGLSIGFLLNGSVVVETIFGWPGIGNLVVSSILSYDYMMIQGSILFVAIIFLVINFIVDLLYVWANPEIRYDRTS
>Mature_316_residues
MLREYFIRRLLYLIPILIFISFLSFSLIYIAPGDPAEIMMTSPGGGYDEAAVEQFRVAHGLDQPFIVQYMTWLKNAATGD
LGYSYMSEQPVFETVINAFKNTLTLSALALVIALIIAIPLGIISAVKHNTIFDSLCRFGALIGVSMPNFWQAYLMIIVFS
VILHWLPGGGFGHGTDISYMILPALVLGTGSAAVMMRMVRSSMLDVLGKEYIQTARAKGLSEATVLMRHALKNALVPIIT
VVGLSIGFLLNGSVVVETIFGWPGIGNLVVSSILSYDYMMIQGSILFVAIIFLVINFIVDLLYVWANPEIRYDRTS

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=310, Percent_Identity=43.8709677419355, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=39.8826979472141, Blast_Score=242, Evalue=2e-65,
Organism=Escherichia coli, GI1789888, Length=311, Percent_Identity=41.4790996784566, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1787497, Length=310, Percent_Identity=36.7741935483871, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787761, Length=329, Percent_Identity=37.6899696048632, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=30.5970149253731, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788504, Length=359, Percent_Identity=26.4623955431755, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34825; Mature: 34825

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLREYFIRRLLYLIPILIFISFLSFSLIYIAPGDPAEIMMTSPGGGYDEAAVEQFRVAHG
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHC
LDQPFIVQYMTWLKNAATGDLGYSYMSEQPVFETVINAFKNTLTLSALALVIALIIAIPL
CCCHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIISAVKHNTIFDSLCRFGALIGVSMPNFWQAYLMIIVFSVILHWLPGGGFGHGTDISYM
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
ILPALVLGTGSAAVMMRMVRSSMLDVLGKEYIQTARAKGLSEATVLMRHALKNALVPIIT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VVGLSIGFLLNGSVVVETIFGWPGIGNLVVSSILSYDYMMIQGSILFVAIIFLVINFIVD
HHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLYVWANPEIRYDRTS
HHHHHCCCCEECCCCC
>Mature Secondary Structure
MLREYFIRRLLYLIPILIFISFLSFSLIYIAPGDPAEIMMTSPGGGYDEAAVEQFRVAHG
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHC
LDQPFIVQYMTWLKNAATGDLGYSYMSEQPVFETVINAFKNTLTLSALALVIALIIAIPL
CCCHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIISAVKHNTIFDSLCRFGALIGVSMPNFWQAYLMIIVFSVILHWLPGGGFGHGTDISYM
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
ILPALVLGTGSAAVMMRMVRSSMLDVLGKEYIQTARAKGLSEATVLMRHALKNALVPIIT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VVGLSIGFLLNGSVVVETIFGWPGIGNLVVSSILSYDYMMIQGSILFVAIIFLVINFIVD
HHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLYVWANPEIRYDRTS
HHHHHCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]