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The map label for this gene is udg [H]

Identifier: 124265799

GI number: 124265799

Start: 637582

End: 638910

Strand: Direct

Name: udg [H]

Synonym: Mpe_A0606

Alternate gene names: 124265799

Gene position: 637582-638910 (Clockwise)

Preceding gene: 124265798

Following gene: 124265800

Centisome position: 15.77

GC content: 69.45

Gene sequence:

>1329_bases
ATGAAGATCACCGTGGTGGGTACCGGCTATGTCGGACTGGTCACTGGCGCGTGCCTGGCCGAAATGGGCAACCACGTGCT
GTGCCTGGACCTCGATGCGCGCAAGATCGAGATGCTCAATGCCGGCGGCATCCCGATCCACGAGCCGGGGCTGGAAGAGG
TGGTCCAGCGCAACGCGGCCGCGAAGCGGCTGGAGTTCACCACCGACGTCGACCGCGCGGTGGCGCACGGCACGTTGCAG
TTCATCGCGGTCGGCACGCCGCCCGACGAGGACGGCTCAGCGGACCTGCAGTACGTGGTGGCGGCGGCACGCGCGATCGG
CGAGCGCATGACCGACTACAAGGTCGTCATCGACAAGAGCACGGTGCCGGTCGGCACCTCGGACAAGGTGCGCGCGGCCA
TCGACGCGGCGCTGGCGGCGCGCGGCGTGACGCTCGAGTTCGCCGTCGTCAGCAACCCCGAGTTCCTGAAGGAGGGTGCC
GCGGTGGCCGACTTCATGCGGCCCGACCGCGTGGTGATCGGCGCCGACGACGAGCGTGCCATCCTGCTGATGCGTTCGCT
TTACGCGCCCTACGTGCGCAATCGCGACCGCGTGCTCGTGATGGACCTGAAGAGCGCCGAGTTCACCAAGTACGCCGCGA
ACTCCATGCTCGCGACCCGCATCAGCTTCATGAACGAGCTGTCGCGCGTTGCCGAGGCGGTGGGAGCCGACATCGAGCTG
GTGCGCCAGGGCATCGGCAGCGATCCGCGCATCGGCACCCAGTTCCTCTACGCCGGCTGCGGCTATGGCGGCTCCTGCTT
CCCGAAGGACGTGAAGGCGCTGATCCGCTCGGCGAGCGAGGCGGGTCAGGAGCTCGAGCTGCTGAGCGCCGTGGAGTCGG
TCAACGAGCGCCAGAAGCAGGTGCTGGGCGACAAGATCATCGCCCGCTTCGGCGCCGACCTGAGCGGACGGCGCTTCGCG
CTCTGGGGCCTGGCCTTCAAGCCCGGCACCGACGACATGCGCGAGGCGCCCAGCCGTGTGCTGATCGAGCGGCTCACCGC
GGCGGGGGCGGAGGTCACCGCCTACGACCCGGTGGCGATGGCCGAGGCCCGCCGCGCGATGCCCGGGCAGGCCGGGCTGC
GCTATGCCGATTCGGCGGTGGCCGCGCTGGAAGGGGCTGACGCGCTGGTGATCGTGACCGAGTGGAAGGAGTTCCGCAGC
CCCGATTTCGACGCGATCCGGAGCACGCTGCGCACGCCGCTGGTGTTCGACGGGCGCAACCTGTTCGAGCCGGCGCTGAT
GAAGCAGCTCGGCATCGAGTACCACGCGATCGGCCGCCCGAGCGCATGA

Upstream 100 bases:

>100_bases
GAACCCTCGCCTGCCCGCCTGGTTGAACGCCCTGGCGCCGCTGCGCACGCACCGGTTGTGCTGGCTCGAGAAACTCTGAA
GAACCGAAAGGGATGAAGCG

Downstream 100 bases:

>100_bases
CCGCGCCGCCCTTCCTGCCCTTCGCGCTGCCCGAGATCGGCGAGGAGGAGATCGCCGAGGTCGTCGACACGCTGCGCTCG
GGCTGGGTCACCACCGGGCC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKITVVGTGYVGLVTGACLAEMGNHVLCLDLDARKIEMLNAGGIPIHEPGLEEVVQRNAAAKRLEFTTDVDRAVAHGTLQ
FIAVGTPPDEDGSADLQYVVAAARAIGERMTDYKVVIDKSTVPVGTSDKVRAAIDAALAARGVTLEFAVVSNPEFLKEGA
AVADFMRPDRVVIGADDERAILLMRSLYAPYVRNRDRVLVMDLKSAEFTKYAANSMLATRISFMNELSRVAEAVGADIEL
VRQGIGSDPRIGTQFLYAGCGYGGSCFPKDVKALIRSASEAGQELELLSAVESVNERQKQVLGDKIIARFGADLSGRRFA
LWGLAFKPGTDDMREAPSRVLIERLTAAGAEVTAYDPVAMAEARRAMPGQAGLRYADSAVAALEGADALVIVTEWKEFRS
PDFDAIRSTLRTPLVFDGRNLFEPALMKQLGIEYHAIGRPSA

Sequences:

>Translated_442_residues
MKITVVGTGYVGLVTGACLAEMGNHVLCLDLDARKIEMLNAGGIPIHEPGLEEVVQRNAAAKRLEFTTDVDRAVAHGTLQ
FIAVGTPPDEDGSADLQYVVAAARAIGERMTDYKVVIDKSTVPVGTSDKVRAAIDAALAARGVTLEFAVVSNPEFLKEGA
AVADFMRPDRVVIGADDERAILLMRSLYAPYVRNRDRVLVMDLKSAEFTKYAANSMLATRISFMNELSRVAEAVGADIEL
VRQGIGSDPRIGTQFLYAGCGYGGSCFPKDVKALIRSASEAGQELELLSAVESVNERQKQVLGDKIIARFGADLSGRRFA
LWGLAFKPGTDDMREAPSRVLIERLTAAGAEVTAYDPVAMAEARRAMPGQAGLRYADSAVAALEGADALVIVTEWKEFRS
PDFDAIRSTLRTPLVFDGRNLFEPALMKQLGIEYHAIGRPSA
>Mature_442_residues
MKITVVGTGYVGLVTGACLAEMGNHVLCLDLDARKIEMLNAGGIPIHEPGLEEVVQRNAAAKRLEFTTDVDRAVAHGTLQ
FIAVGTPPDEDGSADLQYVVAAARAIGERMTDYKVVIDKSTVPVGTSDKVRAAIDAALAARGVTLEFAVVSNPEFLKEGA
AVADFMRPDRVVIGADDERAILLMRSLYAPYVRNRDRVLVMDLKSAEFTKYAANSMLATRISFMNELSRVAEAVGADIEL
VRQGIGSDPRIGTQFLYAGCGYGGSCFPKDVKALIRSASEAGQELELLSAVESVNERQKQVLGDKIIARFGADLSGRRFA
LWGLAFKPGTDDMREAPSRVLIERLTAAGAEVTAYDPVAMAEARRAMPGQAGLRYADSAVAALEGADALVIVTEWKEFRS
PDFDAIRSTLRTPLVFDGRNLFEPALMKQLGIEYHAIGRPSA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=464, Percent_Identity=35.5603448275862, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI296040438, Length=366, Percent_Identity=35.2459016393443, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI296040443, Length=311, Percent_Identity=34.7266881028939, Blast_Score=175, Evalue=6e-44,
Organism=Escherichia coli, GI1788340, Length=361, Percent_Identity=31.5789473684211, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI48994968, Length=420, Percent_Identity=27.6190476190476, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17560350, Length=459, Percent_Identity=34.8583877995643, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI17136908, Length=464, Percent_Identity=34.4827586206897, Blast_Score=254, Evalue=7e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 47599; Mature: 47599

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITVVGTGYVGLVTGACLAEMGNHVLCLDLDARKIEMLNAGGIPIHEPGLEEVVQRNAA
CEEEEEECCHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHH
AKRLEFTTDVDRAVAHGTLQFIAVGTPPDEDGSADLQYVVAAARAIGERMTDYKVVIDKS
HHHHCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC
TVPVGTSDKVRAAIDAALAARGVTLEFAVVSNPEFLKEGAAVADFMRPDRVVIGADDERA
CCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHCCHHHHHHCCCCEEEEECCCCHH
ILLMRSLYAPYVRNRDRVLVMDLKSAEFTKYAANSMLATRISFMNELSRVAEAVGADIEL
HHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRQGIGSDPRIGTQFLYAGCGYGGSCFPKDVKALIRSASEAGQELELLSAVESVNERQKQ
HHHCCCCCCCCCHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGDKIIARFGADLSGRRFALWGLAFKPGTDDMREAPSRVLIERLTAAGAEVTAYDPVAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCHHH
AEARRAMPGQAGLRYADSAVAALEGADALVIVTEWKEFRSPDFDAIRSTLRTPLVFDGRN
HHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHCCCEEECCCC
LFEPALMKQLGIEYHAIGRPSA
HHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure
MKITVVGTGYVGLVTGACLAEMGNHVLCLDLDARKIEMLNAGGIPIHEPGLEEVVQRNAA
CEEEEEECCHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHH
AKRLEFTTDVDRAVAHGTLQFIAVGTPPDEDGSADLQYVVAAARAIGERMTDYKVVIDKS
HHHHCCHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC
TVPVGTSDKVRAAIDAALAARGVTLEFAVVSNPEFLKEGAAVADFMRPDRVVIGADDERA
CCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHCCHHHHHHCCCCEEEEECCCCHH
ILLMRSLYAPYVRNRDRVLVMDLKSAEFTKYAANSMLATRISFMNELSRVAEAVGADIEL
HHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRQGIGSDPRIGTQFLYAGCGYGGSCFPKDVKALIRSASEAGQELELLSAVESVNERQKQ
HHHCCCCCCCCCHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGDKIIARFGADLSGRRFALWGLAFKPGTDDMREAPSRVLIERLTAAGAEVTAYDPVAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCHHH
AEARRAMPGQAGLRYADSAVAALEGADALVIVTEWKEFRSPDFDAIRSTLRTPLVFDGRN
HHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHCCCEEECCCC
LFEPALMKQLGIEYHAIGRPSA
HHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]