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The map label for this gene is phnW [H]

Identifier: 124265755

GI number: 124265755

Start: 594410

End: 595537

Strand: Direct

Name: phnW [H]

Synonym: Mpe_A0562

Alternate gene names: 124265755

Gene position: 594410-595537 (Clockwise)

Preceding gene: 124265754

Following gene: 124265756

Centisome position: 14.7

GC content: 68.35

Gene sequence:

>1128_bases
ATGCCTGGCTTGCTGCCGAACGTGGACCCTGAGGGTTTGCTCGAGTACTCGGTGGTCTACACCGACCGTGCCCTCAACCA
CATGTCCCAGAGTTTCCAGGGGGTCATGCGTGACATCTCGGCCACGCTGAAGCGCGTCTACAACGCGAAGTCGGCGGTCA
TCGTGCCCGGCAGCGGCACCTTTGGCATGGAGGCGGTGGCGCGACAGTTCGCCACCGACCGCAAGGTCCTGGTCATCCGC
AACGGCTGGTTCAGCTACCGGTGGACGCAGATTCTCGACATGGGCCGCATCGCTTCCGACGCCACGGTGCTGAAGGCTCG
CCGCACCGGGCCGGGCGCGCAGGCACCCTTCGCGCCGGCGCCGATCGGCGAGGTGGTGGCCACGATCCGCGCGGAGCGTC
CCGCGGTCGTGTTCGCGCCACACGTCGAGACCTCGGCCGGGATGATCCTGCCCGATGCCTACCTGCGCGCCGTGGCCGAC
GCGGTGCACGAGGTCGGCGGGCTGTTCGTGCTCGATTGCATTGCATCGGGCACCTTGTGGGTCGACATGCAGGCGACCGG
CGTCGACGTGCTGGTCAGCGCGCCCCAGAAGGGTTGGAGCGGCTCGCCCTGCTGCGCGCTGATCGCGATGAGCGATCTGG
CGCGTGGGCGCATCGACGGGACGCAGAGCACCAGCTTCGCCTGCGACCTGCGCAAGTGGATGCAGATCATGGAGGCCTAC
GAGGCCGGTGGCTACGCCTATCACGCCACGATGCCGACCGACTCGCTGGCCCGCGTGCGCGATGTGATGCGCGAGACCGA
GGCCTATGGCTTCGAGAAGGTGCGCGCGGAACAGCAGCAGCTGGGCGAGCAGGTGCGTGCGCTGCTGGTGCGCAAGGGCC
TGCGCAGCGTGGCGGCCGAAGGCTTCCAGGCGCCCTGCGTGGTGGTCAGCTACACCGAGGATCCGGCCATCCAGTCGGGT
CAGAAGTTCCTCGGGCTGGGCCTGCAGGTGGCCGCCGGCGTGCCCTTGCAGTGCGACGAGGGGGCCGACTTCCGGACCTT
CCGCATCGGCCTGTTCGGCCTCGACAAGCTGCATCACATCGAGCGCACGGTCCGTCACCTAGACGACGCGCTGAACCGCA
TCCTCTAG

Upstream 100 bases:

>100_bases
CATCGCTCTACGGCGATGGCAGGCCTTCGTGCAGTGCCCCATGGCCCGCATGAAGGCCGAAAACCCCTGCAACAGAGACA
GTTTCTCAGTGGAGTGATCG

Downstream 100 bases:

>100_bases
GGCTTTTCAACGCGATCGGGGCACCCGGCACGAAGAGCCGGCCGGCCGCTGGCGGCCTGGTCTACTCGACCGAGCTCGGC
CGGACCTGCCCGGCCTGCCG

Product: serine-pyruvate aminotransferase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MPGLLPNVDPEGLLEYSVVYTDRALNHMSQSFQGVMRDISATLKRVYNAKSAVIVPGSGTFGMEAVARQFATDRKVLVIR
NGWFSYRWTQILDMGRIASDATVLKARRTGPGAQAPFAPAPIGEVVATIRAERPAVVFAPHVETSAGMILPDAYLRAVAD
AVHEVGGLFVLDCIASGTLWVDMQATGVDVLVSAPQKGWSGSPCCALIAMSDLARGRIDGTQSTSFACDLRKWMQIMEAY
EAGGYAYHATMPTDSLARVRDVMRETEAYGFEKVRAEQQQLGEQVRALLVRKGLRSVAAEGFQAPCVVVSYTEDPAIQSG
QKFLGLGLQVAAGVPLQCDEGADFRTFRIGLFGLDKLHHIERTVRHLDDALNRIL

Sequences:

>Translated_375_residues
MPGLLPNVDPEGLLEYSVVYTDRALNHMSQSFQGVMRDISATLKRVYNAKSAVIVPGSGTFGMEAVARQFATDRKVLVIR
NGWFSYRWTQILDMGRIASDATVLKARRTGPGAQAPFAPAPIGEVVATIRAERPAVVFAPHVETSAGMILPDAYLRAVAD
AVHEVGGLFVLDCIASGTLWVDMQATGVDVLVSAPQKGWSGSPCCALIAMSDLARGRIDGTQSTSFACDLRKWMQIMEAY
EAGGYAYHATMPTDSLARVRDVMRETEAYGFEKVRAEQQQLGEQVRALLVRKGLRSVAAEGFQAPCVVVSYTEDPAIQSG
QKFLGLGLQVAAGVPLQCDEGADFRTFRIGLFGLDKLHHIERTVRHLDDALNRIL
>Mature_374_residues
PGLLPNVDPEGLLEYSVVYTDRALNHMSQSFQGVMRDISATLKRVYNAKSAVIVPGSGTFGMEAVARQFATDRKVLVIRN
GWFSYRWTQILDMGRIASDATVLKARRTGPGAQAPFAPAPIGEVVATIRAERPAVVFAPHVETSAGMILPDAYLRAVADA
VHEVGGLFVLDCIASGTLWVDMQATGVDVLVSAPQKGWSGSPCCALIAMSDLARGRIDGTQSTSFACDLRKWMQIMEAYE
AGGYAYHATMPTDSLARVRDVMRETEAYGFEKVRAEQQQLGEQVRALLVRKGLRSVAAEGFQAPCVVVSYTEDPAIQSGQ
KFLGLGLQVAAGVPLQCDEGADFRTFRIGLFGLDKLHHIERTVRHLDDALNRIL

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=277, Percent_Identity=25.9927797833935, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536281, Length=369, Percent_Identity=25.7452574525745, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321079, Length=277, Percent_Identity=27.4368231046931, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 40762; Mature: 40631

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGLLPNVDPEGLLEYSVVYTDRALNHMSQSFQGVMRDISATLKRVYNAKSAVIVPGSGT
CCCCCCCCCCCHHHEEHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
FGMEAVARQFATDRKVLVIRNGWFSYRWTQILDMGRIASDATVLKARRTGPGAQAPFAPA
CCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCCCC
PIGEVVATIRAERPAVVFAPHVETSAGMILPDAYLRAVADAVHEVGGLFVLDCIASGTLW
CHHHHHHHHHCCCCEEEEECCCCCCCCEECCHHHHHHHHHHHHHHCCHHEEHHHCCCEEE
VDMQATGVDVLVSAPQKGWSGSPCCALIAMSDLARGRIDGTQSTSFACDLRKWMQIMEAY
EEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
EAGGYAYHATMPTDSLARVRDVMRETEAYGFEKVRAEQQQLGEQVRALLVRKGLRSVAAE
HCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFQAPCVVVSYTEDPAIQSGQKFLGLGLQVAAGVPLQCDEGADFRTFRIGLFGLDKLHHI
CCCCCEEEEEECCCCCHHCCCHHHHCCHHHHCCCCEECCCCCCEEEEEEEHHHHHHHHHH
ERTVRHLDDALNRIL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGLLPNVDPEGLLEYSVVYTDRALNHMSQSFQGVMRDISATLKRVYNAKSAVIVPGSGT
CCCCCCCCCCHHHEEHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
FGMEAVARQFATDRKVLVIRNGWFSYRWTQILDMGRIASDATVLKARRTGPGAQAPFAPA
CCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCCCC
PIGEVVATIRAERPAVVFAPHVETSAGMILPDAYLRAVADAVHEVGGLFVLDCIASGTLW
CHHHHHHHHHCCCCEEEEECCCCCCCCEECCHHHHHHHHHHHHHHCCHHEEHHHCCCEEE
VDMQATGVDVLVSAPQKGWSGSPCCALIAMSDLARGRIDGTQSTSFACDLRKWMQIMEAY
EEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
EAGGYAYHATMPTDSLARVRDVMRETEAYGFEKVRAEQQQLGEQVRALLVRKGLRSVAAE
HCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFQAPCVVVSYTEDPAIQSGQKFLGLGLQVAAGVPLQCDEGADFRTFRIGLFGLDKLHHI
CCCCCEEEEEECCCCCHHCCCHHHHCCHHHHCCCCEECCCCCCEEEEEEEHHHHHHHHHH
ERTVRHLDDALNRIL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA