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The map label for this gene is gra-orf6 [H]

Identifier: 124265745

GI number: 124265745

Start: 585299

End: 586078

Strand: Direct

Name: gra-orf6 [H]

Synonym: Mpe_A0552

Alternate gene names: 124265745

Gene position: 585299-586078 (Clockwise)

Preceding gene: 124265742

Following gene: 124265746

Centisome position: 14.47

GC content: 71.67

Gene sequence:

>780_bases
ATGAGCGTCGATTCCCGTCCCGTGGTGCTCGTCACCGGTGCCGCACGGCGCGTCGGCCGCGCCATCGCGCTCGAACTGGC
CGCGCACGGCTTCGACGTGGCGGTGCACAGCCATCGGGCCAGCGACGAGTCGATCGACACGCTGCAGGCAGCCCGCGCGG
CCGGTGCGCGCGCCGAGGCTTTCGTGGCCGACCTGGCCGACGAGACCGCCTGCCGCGCGCTGCTGCCTGCCGTGGCCGAG
CGCATGGGGCGCATCGACGCGGTGGTGAACAACGCCTCGCGCTTCGAGTACGACGGCGCAGGGGACTGCAGCTACGCGTC
GATGGCCGAGCACTGGCAGGTCAACACCGCCGCGCCGGTGCTGCTGGCGGCCGCGCTGCACCAGCGGCTGAGCGGTAGCT
CGGGGCGTGGCTGTGTCGTCAACCTGCTCGACCAGAAGCTGTGGAACCCGAATCCGGATCATTTTTCGTACACGCTGTCG
AAGGCCGCGCTGGAGGCGGCGACCACGCTGCAGGCGCAGGCCTTCGCGCCCACGCTGCGCGTGGTTGGTGTTGCGCCCGG
CGTCACGCTGCCGTCGGGACCGATGGACAGCGCGGAGTTCGTGCGCGCACACGCGATGACGCCGCTGCGCCGTTCGTCGA
CGCCCGAGGACGTGGCTCGTGCCGTGCGCTTCCTGATCGAGTCGCCGGCCATCACCGGCACCACGCTGCTGGTCGACGGC
GGGCAGCACCTGTCTGCGCAGCCGCGCGACGTGCTGTTCCTTGCGCGCGAGGGGGTTTGA

Upstream 100 bases:

>100_bases
CCGTTGCGATCCGCGCTTTCAAGGCCTCTTGCAGGCTCGGCAAAGGGGGGCTGGCTACACTGACGGGGCTCGATTCCACC
CCTCCATTGTCCCGCACGAC

Downstream 100 bases:

>100_bases
GGTGCCGCACTGGACCCTGCATCCCCGGCTGGCGGCGTGCCGGCGCGTGTTCCTGAAGTCGTATGCGCTGCCGGTGCGCA
TCGGCGTGCACGACTTCGAG

Product: putative oxidoreductase

Products: NA

Alternate protein names: ORF6 [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSVDSRPVVLVTGAARRVGRAIALELAAHGFDVAVHSHRASDESIDTLQAARAAGARAEAFVADLADETACRALLPAVAE
RMGRIDAVVNNASRFEYDGAGDCSYASMAEHWQVNTAAPVLLAAALHQRLSGSSGRGCVVNLLDQKLWNPNPDHFSYTLS
KAALEAATTLQAQAFAPTLRVVGVAPGVTLPSGPMDSAEFVRAHAMTPLRRSSTPEDVARAVRFLIESPAITGTTLLVDG
GQHLSAQPRDVLFLAREGV

Sequences:

>Translated_259_residues
MSVDSRPVVLVTGAARRVGRAIALELAAHGFDVAVHSHRASDESIDTLQAARAAGARAEAFVADLADETACRALLPAVAE
RMGRIDAVVNNASRFEYDGAGDCSYASMAEHWQVNTAAPVLLAAALHQRLSGSSGRGCVVNLLDQKLWNPNPDHFSYTLS
KAALEAATTLQAQAFAPTLRVVGVAPGVTLPSGPMDSAEFVRAHAMTPLRRSSTPEDVARAVRFLIESPAITGTTLLVDG
GQHLSAQPRDVLFLAREGV
>Mature_258_residues
SVDSRPVVLVTGAARRVGRAIALELAAHGFDVAVHSHRASDESIDTLQAARAAGARAEAFVADLADETACRALLPAVAER
MGRIDAVVNNASRFEYDGAGDCSYASMAEHWQVNTAAPVLLAAALHQRLSGSSGRGCVVNLLDQKLWNPNPDHFSYTLSK
AALEAATTLQAQAFAPTLRVVGVAPGVTLPSGPMDSAEFVRAHAMTPLRRSSTPEDVARAVRFLIESPAITGTTLLVDGG
QHLSAQPRDVLFLAREGV

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=29.7959183673469, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=31.4285714285714, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=28.7449392712551, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787891, Length=239, Percent_Identity=28.4518828451883, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=27.9352226720648, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=27.9527559055118, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=26.6393442622951, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=30.3501945525292, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=24.8148148148148, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=27.0833333333333, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=274, Percent_Identity=27.007299270073, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=263, Percent_Identity=27.3764258555133, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=27.9245283018868, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=31.7829457364341, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=28.3400809716599, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=27.3809523809524, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=29.9610894941634, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27271; Mature: 27140

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDSRPVVLVTGAARRVGRAIALELAAHGFDVAVHSHRASDESIDTLQAARAAGARAEA
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHH
FVADLADETACRALLPAVAERMGRIDAVVNNASRFEYDGAGDCSYASMAEHWQVNTAAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHCCCCCHHHH
LLAAALHQRLSGSSGRGCVVNLLDQKLWNPNPDHFSYTLSKAALEAATTLQAQAFAPTLR
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
VVGVAPGVTLPSGPMDSAEFVRAHAMTPLRRSSTPEDVARAVRFLIESPAITGTTLLVDG
EEEECCCCCCCCCCCCHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEC
GQHLSAQPRDVLFLAREGV
CCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
SVDSRPVVLVTGAARRVGRAIALELAAHGFDVAVHSHRASDESIDTLQAARAAGARAEA
CCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHH
FVADLADETACRALLPAVAERMGRIDAVVNNASRFEYDGAGDCSYASMAEHWQVNTAAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHCCCCCHHHH
LLAAALHQRLSGSSGRGCVVNLLDQKLWNPNPDHFSYTLSKAALEAATTLQAQAFAPTLR
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
VVGVAPGVTLPSGPMDSAEFVRAHAMTPLRRSSTPEDVARAVRFLIESPAITGTTLLVDG
EEEECCCCCCCCCCCCHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEC
GQHLSAQPRDVLFLAREGV
CCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2583128; 9831526 [H]