Definition | Methylibium petroleiphilum PM1 chromosome, complete genome. |
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Accession | NC_008825 |
Length | 4,044,195 |
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The map label for this gene is tpa [H]
Identifier: 124265564
GI number: 124265564
Start: 407975
End: 409333
Strand: Direct
Name: tpa [H]
Synonym: Mpe_A0371
Alternate gene names: 124265564
Gene position: 407975-409333 (Clockwise)
Preceding gene: 124265563
Following gene: 124265565
Centisome position: 10.09
GC content: 71.16
Gene sequence:
>1359_bases ATGGGCGACAGCCTCAACGCCGCGCTGCTGCAGCGCGACCACCGCCACCTGGTGCATTCGCTGCACAACGAGGCCGCCCA CCTGGCCGGCAACGTGTGGGTGAAGGGCGAGGGCACCACGCTGACCGACGCCGACGGCAAGCGCTACGTCGACGCCATGT CGGGCCTGTGGAACGTGACCCTGGGCTACGGCCGCCGCGAACTGGTGGACGCCGCCGCCGCGCAGATGGGCGAGCTGGCC TATGCCTCCGGCTACGCCGGCAGCACCAACCTGCGGGCGATGGAGCTGGCCGAGAAGCTGGCGGCCGACCGCGTGTACCC CAACATGCACCGCTTCTTCTTCACCTCCGGGGGCGGCGAGTCGACCGACAGCACCATCAAGACCGCGCGCTACTACTGGA AGGCGCAGGGCAAGCCCGGCAAATTCAAGACCCTCAGCGTGATGGGCGGCTACCACGGCGTGACGCTGGCCGCCATGTGC GCCACCGGCATGCCGGCCTACTGGCCGTCCTTCGAGCCGCGCATGCCGGGCTTCGTGCACATACCGAACCACGACGCCTA CCGCTACACCGTGCCGCCCGGTGGCGACCCGGCCACCGCCGCGGCCGACGAGCTGGAGCGCGCCATCCTGGCCGAGGGCC CCGACACGGTGGCCCTGTTCATCGCCGAGCCGGTGATGGGCGGCGGCGCCTATGTGCCGCCGGCGGGCTACTTCCGCCGC ATCCGCGAGATCTGCGACCGCTACGACGTGCTGTTCGCCACCGACGAAGTCATCACCGGCTTCGGCCGCACCGGCAAGCT GTTTGCGCTGGGCCACTGGGGCAGCGACGTGCAGCCCGACCTGGTGCAGTTTGCCAAGGGCATCACCAGCGGCTACGTGC CGATGGGCGGCGTGGGGTTGTCCGACAAGGTGGCCGCGGTGTTCGACCGCCCGGGCGCCGACACCTGGATGCACTGCTAC ACCTACAGCGGCCACCCGGTGGCCTGCGCGGTGGCGCTGGCCACGCTGGACGTCATAGAACGCGAAGGCCTGCTGGCGCG CGCGCAGGTGCTGGGCGACCGGCTGCTGCGCGGCCTGCGCGGCGCGCTGGGTGGCCACCCGAACGTGGGCGACATCCGCG GCCTGGGGCTGATAGCCGCGGTGGAACTGGTGGAAGACCGCTTCTCCAAGAAGTCCTTCGACCCCGCCCGCAAGATGGGC CCGCAGGTGCTGGCACAGGTGCGCCAGCGCGGCGTGATCACGCGCGGCCGCGGCGACACCATTTACCTGGGCCCGGCGCT GGTGAGCGACGAGGCCACCATCGACCGGATCGTGGAGGCGGTGGCGGAGGGGGTGGGGGCGCTGTTGCCTGCTGCTTGA
Upstream 100 bases:
>100_bases GCCCACGTGTCGCGCCGCGAGCGGCTGTTCGTCGACGAACACACGCTGGTGGACACCGGCGTCTGAACCCGCGACCCCCG CAACGCACGGAGCCAGCCAC
Downstream 100 bases:
>100_bases GCGCCCACCACGTCGCGCGCTGAGCGCGAGCGGGATCGAAACGCCTTCTTCTTTTCACGGCGTCGGGTACTCAGCCGACG CCGTGGTCATTTGGGCCGCC
Product: aminotransferase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 452; Mature: 451
Protein sequence:
>452_residues MGDSLNAALLQRDHRHLVHSLHNEAAHLAGNVWVKGEGTTLTDADGKRYVDAMSGLWNVTLGYGRRELVDAAAAQMGELA YASGYAGSTNLRAMELAEKLAADRVYPNMHRFFFTSGGGESTDSTIKTARYYWKAQGKPGKFKTLSVMGGYHGVTLAAMC ATGMPAYWPSFEPRMPGFVHIPNHDAYRYTVPPGGDPATAAADELERAILAEGPDTVALFIAEPVMGGGAYVPPAGYFRR IREICDRYDVLFATDEVITGFGRTGKLFALGHWGSDVQPDLVQFAKGITSGYVPMGGVGLSDKVAAVFDRPGADTWMHCY TYSGHPVACAVALATLDVIEREGLLARAQVLGDRLLRGLRGALGGHPNVGDIRGLGLIAAVELVEDRFSKKSFDPARKMG PQVLAQVRQRGVITRGRGDTIYLGPALVSDEATIDRIVEAVAEGVGALLPAA
Sequences:
>Translated_452_residues MGDSLNAALLQRDHRHLVHSLHNEAAHLAGNVWVKGEGTTLTDADGKRYVDAMSGLWNVTLGYGRRELVDAAAAQMGELA YASGYAGSTNLRAMELAEKLAADRVYPNMHRFFFTSGGGESTDSTIKTARYYWKAQGKPGKFKTLSVMGGYHGVTLAAMC ATGMPAYWPSFEPRMPGFVHIPNHDAYRYTVPPGGDPATAAADELERAILAEGPDTVALFIAEPVMGGGAYVPPAGYFRR IREICDRYDVLFATDEVITGFGRTGKLFALGHWGSDVQPDLVQFAKGITSGYVPMGGVGLSDKVAAVFDRPGADTWMHCY TYSGHPVACAVALATLDVIEREGLLARAQVLGDRLLRGLRGALGGHPNVGDIRGLGLIAAVELVEDRFSKKSFDPARKMG PQVLAQVRQRGVITRGRGDTIYLGPALVSDEATIDRIVEAVAEGVGALLPAA >Mature_451_residues GDSLNAALLQRDHRHLVHSLHNEAAHLAGNVWVKGEGTTLTDADGKRYVDAMSGLWNVTLGYGRRELVDAAAAQMGELAY ASGYAGSTNLRAMELAEKLAADRVYPNMHRFFFTSGGGESTDSTIKTARYYWKAQGKPGKFKTLSVMGGYHGVTLAAMCA TGMPAYWPSFEPRMPGFVHIPNHDAYRYTVPPGGDPATAAADELERAILAEGPDTVALFIAEPVMGGGAYVPPAGYFRRI REICDRYDVLFATDEVITGFGRTGKLFALGHWGSDVQPDLVQFAKGITSGYVPMGGVGLSDKVAAVFDRPGADTWMHCYT YSGHPVACAVALATLDVIEREGLLARAQVLGDRLLRGLRGALGGHPNVGDIRGLGLIAAVELVEDRFSKKSFDPARKMGP QVLAQVRQRGVITRGRGDTIYLGPALVSDEATIDRIVEAVAEGVGALLPAA
Specific function: Catalyzes the degradation of taurine into alanine and sulfoacetaldehyde. Can also transaminate hypotaurine (2- aminosulfinate), beta-alanine and with low activity cysteine and 3-aminopropanesulfonate. In addition to pyruvate, 2-ketobutyrate and oxaloaceta
COG id: COG0161
COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]
Homologues:
Organism=Homo sapiens, GI37574042, Length=431, Percent_Identity=28.7703016241299, Blast_Score=159, Evalue=4e-39, Organism=Homo sapiens, GI4557809, Length=444, Percent_Identity=29.7297297297297, Blast_Score=159, Evalue=5e-39, Organism=Homo sapiens, GI226442705, Length=431, Percent_Identity=29.0023201856148, Blast_Score=156, Evalue=4e-38, Organism=Homo sapiens, GI226442709, Length=404, Percent_Identity=29.2079207920792, Blast_Score=150, Evalue=3e-36, Organism=Homo sapiens, GI24119277, Length=396, Percent_Identity=30.3030303030303, Blast_Score=143, Evalue=3e-34, Organism=Homo sapiens, GI284507298, Length=334, Percent_Identity=32.3353293413174, Blast_Score=133, Evalue=3e-31, Organism=Homo sapiens, GI13994255, Length=432, Percent_Identity=28.4722222222222, Blast_Score=130, Evalue=3e-30, Organism=Homo sapiens, GI188536080, Length=442, Percent_Identity=25.7918552036199, Blast_Score=101, Evalue=1e-21, Organism=Homo sapiens, GI38679950, Length=442, Percent_Identity=25.7918552036199, Blast_Score=101, Evalue=1e-21, Organism=Homo sapiens, GI38679946, Length=442, Percent_Identity=25.7918552036199, Blast_Score=101, Evalue=1e-21, Organism=Escherichia coli, GI145693181, Length=424, Percent_Identity=32.7830188679245, Blast_Score=199, Evalue=3e-52, Organism=Escherichia coli, GI1789016, Length=417, Percent_Identity=30.6954436450839, Blast_Score=164, Evalue=1e-41, Organism=Escherichia coli, GI1789759, Length=422, Percent_Identity=30.3317535545024, Blast_Score=160, Evalue=2e-40, Organism=Escherichia coli, GI1786991, Length=446, Percent_Identity=28.6995515695067, Blast_Score=143, Evalue=3e-35, Organism=Escherichia coli, GI1787560, Length=374, Percent_Identity=33.1550802139037, Blast_Score=141, Evalue=7e-35, Organism=Escherichia coli, GI1788044, Length=415, Percent_Identity=30.6024096385542, Blast_Score=141, Evalue=1e-34, Organism=Escherichia coli, GI1786349, Length=328, Percent_Identity=28.9634146341463, Blast_Score=87, Evalue=3e-18, Organism=Caenorhabditis elegans, GI25144271, Length=417, Percent_Identity=27.3381294964029, Blast_Score=154, Evalue=7e-38, Organism=Caenorhabditis elegans, GI32564660, Length=444, Percent_Identity=28.6036036036036, Blast_Score=145, Evalue=3e-35, Organism=Caenorhabditis elegans, GI25144274, Length=299, Percent_Identity=28.7625418060201, Blast_Score=133, Evalue=2e-31, Organism=Caenorhabditis elegans, GI71992977, Length=422, Percent_Identity=26.303317535545, Blast_Score=117, Evalue=8e-27, Organism=Caenorhabditis elegans, GI17541228, Length=405, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=4e-17, Organism=Saccharomyces cerevisiae, GI6323470, Length=439, Percent_Identity=28.0182232346241, Blast_Score=140, Evalue=6e-34, Organism=Saccharomyces cerevisiae, GI6324386, Length=477, Percent_Identity=25.9958071278826, Blast_Score=130, Evalue=4e-31, Organism=Saccharomyces cerevisiae, GI6324432, Length=416, Percent_Identity=25.9615384615385, Blast_Score=125, Evalue=1e-29, Organism=Saccharomyces cerevisiae, GI6321456, Length=387, Percent_Identity=26.8733850129199, Blast_Score=84, Evalue=6e-17, Organism=Drosophila melanogaster, GI21357415, Length=442, Percent_Identity=29.4117647058824, Blast_Score=160, Evalue=2e-39, Organism=Drosophila melanogaster, GI21356575, Length=437, Percent_Identity=30.6636155606407, Blast_Score=150, Evalue=2e-36, Organism=Drosophila melanogaster, GI28574759, Length=437, Percent_Identity=28.8329519450801, Blast_Score=139, Evalue=4e-33, Organism=Drosophila melanogaster, GI161085790, Length=463, Percent_Identity=28.2937365010799, Blast_Score=139, Evalue=6e-33, Organism=Drosophila melanogaster, GI281366494, Length=312, Percent_Identity=26.2820512820513, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24667139, Length=312, Percent_Identity=26.2820512820513, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24667143, Length=312, Percent_Identity=26.2820512820513, Blast_Score=80, Evalue=2e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005814 - InterPro: IPR015424 - InterPro: IPR015421 - InterPro: IPR015422 [H]
Pfam domain/function: PF00202 Aminotran_3 [H]
EC number: =2.6.1.77 [H]
Molecular weight: Translated: 48354; Mature: 48222
Theoretical pI: Translated: 6.85; Mature: 6.85
Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00147 ARGINASE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGDSLNAALLQRDHRHLVHSLHNEAAHLAGNVWVKGEGTTLTDADGKRYVDAMSGLWNVT CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCHHHHHHHHCHHEEH LGYGRRELVDAAAAQMGELAYASGYAGSTNLRAMELAEKLAADRVYPNMHRFFFTSGGGE CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCC STDSTIKTARYYWKAQGKPGKFKTLSVMGGYHGVTLAAMCATGMPAYWPSFEPRMPGFVH CCHHHHHHHHEEEEECCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEE IPNHDAYRYTVPPGGDPATAAADELERAILAEGPDTVALFIAEPVMGGGAYVPPAGYFRR CCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHH IREICDRYDVLFATDEVITGFGRTGKLFALGHWGSDVQPDLVQFAKGITSGYVPMGGVGL HHHHHHHHCEEEECHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCC SDKVAAVFDRPGADTWMHCYTYSGHPVACAVALATLDVIEREGLLARAQVLGDRLLRGLR CCCHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH GALGGHPNVGDIRGLGLIAAVELVEDRFSKKSFDPARKMGPQVLAQVRQRGVITRGRGDT HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHCCCEECCCCCE IYLGPALVSDEATIDRIVEAVAEGVGALLPAA EEECCEEECCHHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure GDSLNAALLQRDHRHLVHSLHNEAAHLAGNVWVKGEGTTLTDADGKRYVDAMSGLWNVT CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCHHHHHHHHCHHEEH LGYGRRELVDAAAAQMGELAYASGYAGSTNLRAMELAEKLAADRVYPNMHRFFFTSGGGE CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCC STDSTIKTARYYWKAQGKPGKFKTLSVMGGYHGVTLAAMCATGMPAYWPSFEPRMPGFVH CCHHHHHHHHEEEEECCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEE IPNHDAYRYTVPPGGDPATAAADELERAILAEGPDTVALFIAEPVMGGGAYVPPAGYFRR CCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHH IREICDRYDVLFATDEVITGFGRTGKLFALGHWGSDVQPDLVQFAKGITSGYVPMGGVGL HHHHHHHHCEEEECHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCC SDKVAAVFDRPGADTWMHCYTYSGHPVACAVALATLDVIEREGLLARAQVLGDRLLRGLR CCCHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH GALGGHPNVGDIRGLGLIAAVELVEDRFSKKSFDPARKMGPQVLAQVRQRGVITRGRGDT HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHCCCEECCCCCE IYLGPALVSDEATIDRIVEAVAEGVGALLPAA EEECCEEECCHHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11082195 [H]