Click here to switch to the map view.

The map label for this gene is hldE [H]

Identifier: 124265433

GI number: 124265433

Start: 256198

End: 256677

Strand: Direct

Name: hldE [H]

Synonym: Mpe_A0240

Alternate gene names: 124265433

Gene position: 256198-256677 (Clockwise)

Preceding gene: 124265432

Following gene: 124265436

Centisome position: 6.33

GC content: 71.04

Gene sequence:

>480_bases
ATGAAGCCCCCTGCCTTCCACGGCAAGCTCTGCTCCCGCCGGGCCTTGAGTCAGCGCCTCGGCGAACTCGCGCGGCCGAT
CGTCTTCACCAACGGCGTGTTCGACATCCTGCACCGGGGTCACGTCGAGTACCTGGCGCAGGCGCGCTCGCTCGGCGGCA
GTCTGGTGGTCGCAGTGAACAGCGACGCGTCGGCGCGCGGCCTCGGCAAGGGGCCGGACCGACCGCTGAACCGCGAGGCC
GACCGCGCCGCGGTGCTGGCGGCGCTCGAGAGCGTGAGCCTCGTCACGCTGTTCGACGAGCCGACGCCGGTCGAGTTGCT
GAAGCAGGTGCGACCTGACCTGTACGTCAAGGGCGGTGACTACGACATGGAGACGCTGGCCGAGACCGCGCTGGTGCGCA
GCTGGGGCGGCGGCGCGCTCGCCATCCCGTTCCTGCCTGGCTACTCCACCACCGCGCTGGTGCGCCGCATCCGCGACTGA

Upstream 100 bases:

>100_bases
GCGGCGGCTTCGGCGGCCGGCGGCCCCCCGGGCACCCAGCCGGCCTGATCGAGTCCGCCTCATCGCGGCCGCCCGGCGCG
GGGCACGCGACAATGGCGGC

Downstream 100 bases:

>100_bases
ACCCTGGCGTCAACGCCGGCGCAGCAGCAGCCTGGCGAGCAGTGCCCCGGCGATCGCGCCGGTGCTGTGCGCGAGCGGCG
CGACCGCGATGTCCCAGCCT

Product: putative transferase protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKPPAFHGKLCSRRALSQRLGELARPIVFTNGVFDILHRGHVEYLAQARSLGGSLVVAVNSDASARGLGKGPDRPLNREA
DRAAVLAALESVSLVTLFDEPTPVELLKQVRPDLYVKGGDYDMETLAETALVRSWGGGALAIPFLPGYSTTALVRRIRD

Sequences:

>Translated_159_residues
MKPPAFHGKLCSRRALSQRLGELARPIVFTNGVFDILHRGHVEYLAQARSLGGSLVVAVNSDASARGLGKGPDRPLNREA
DRAAVLAALESVSLVTLFDEPTPVELLKQVRPDLYVKGGDYDMETLAETALVRSWGGGALAIPFLPGYSTTALVRRIRD
>Mature_159_residues
MKPPAFHGKLCSRRALSQRLGELARPIVFTNGVFDILHRGHVEYLAQARSLGGSLVVAVNSDASARGLGKGPDRPLNREA
DRAAVLAALESVSLVTLFDEPTPVELLKQVRPDLYVKGGDYDMETLAETALVRSWGGGALAIPFLPGYSTTALVRRIRD

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=132, Percent_Identity=52.2727272727273, Blast_Score=127, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 17164; Mature: 17164

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPPAFHGKLCSRRALSQRLGELARPIVFTNGVFDILHRGHVEYLAQARSLGGSLVVAVN
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHCCHHHHHHHHHHCCCEEEEEEC
SDASARGLGKGPDRPLNREADRAAVLAALESVSLVTLFDEPTPVELLKQVRPDLYVKGGD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCCEEEECCC
YDMETLAETALVRSWGGGALAIPFLPGYSTTALVRRIRD
CCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKPPAFHGKLCSRRALSQRLGELARPIVFTNGVFDILHRGHVEYLAQARSLGGSLVVAVN
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHCCHHHHHHHHHHCCCEEEEEEC
SDASARGLGKGPDRPLNREADRAAVLAALESVSLVTLFDEPTPVELLKQVRPDLYVKGGD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCCEEEECCC
YDMETLAETALVRSWGGGALAIPFLPGYSTTALVRRIRD
CCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA