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The map label for this gene is atpD [H]

Identifier: 124265390

GI number: 124265390

Start: 211899

End: 213314

Strand: Direct

Name: atpD [H]

Synonym: Mpe_A0197

Alternate gene names: 124265390

Gene position: 211899-213314 (Clockwise)

Preceding gene: 124265389

Following gene: 124265391

Centisome position: 5.24

GC content: 65.75

Gene sequence:

>1416_bases
ATGGCGAACACTCAAGCAGCCGTCGGCAAGATCGTCCAGTGCATCGGCGCTGTCGTGGACGTGGAGTTCCCGCGGGACCA
GATGCCGCGTGTCTATGACGCGCTGAAGATGGAAGGCTCTGCCCTGACGCTCGAGGTGCAGCAGCAGCTCGGCGACGGCG
TGGTCCGTACCATCGCGCTGGGCTCGTCCGACGGCCTGCGCCGCGGCCTGATGGTCAGCAACACCGGCGCGGCGATCACC
GTGCCGGTCGGCAAGGCCACGCTGGGTCGCATCATGGACGTGCTGGGCAGCCCGATCGACGAGCGCGGCCCGGTCAGCGC
CGAGCTGAGCATGCCGATCCACCGCAAGGCGCCGGCCTACGACGAGCTGAGCCCGTCGCAAGAGCTGCTCGAGACCGGCA
TCAAGGTGATCGACCTGATCTGCCCGTTCGCCAAGGGCGGCAAGGTGGGTCTGTTCGGCGGCGCTGGCGTCGGCAAGACC
GTGAACATGATGGAGCTGATCAACAACATCGCCAAGGCCCACTCGGGTCTGTCGGTGTTCGCTGGCGTCGGCGAGCGTAC
CCGCGAGGGCAACGACTTCTATCACGAGATGTCGGACTCGAAGGTCGTGGTCCAGGAGGACCTGACGCAGTCGAAGGTCG
CGATGGTCTACGGCCAGATGAACGAGCCCCCGGGCAACCGTCTGCGCGTTGCGCTGACCGGCCTGACGATCGCCGAGTCC
TTCCGCGACGAAGGCCGTGACGTGCTGTTCTTCGTTGACAACATCTACCGCTACACGCTGGCCGGCACCGAAGTGTCCGC
GCTGCTGGGCCGGATGCCGTCGGCGGTGGGCTACCAGCCGACGCTGGCCGAGGAAATGGGCCGGCTGCAGGAGCGCATCA
CCTCCACCAAGGTGGGCTCGATCACCTCGATCCAGGCCGTCTACGTGCCCGCGGATGACCTCACCGATCCGTCGCCCGCA
ACCACCTTCGCCCACTTGGATGCGACCGTGGTGCTGTCGCGCGACATCGCCTCGCTGGGCATCTACCCCGCGGTGGACCC
GCTGGACTCGACCTCGCGCCAGATCGACCCGAACGTCGTCGGCGAAGAGCACTACAACACCACCCGTGCCGTGCAGCAGG
TGCTGCAGCGCTACAAGGAACTGCGCGACATCATCGCCATTCTCGGCATGGACGAACTGGCGCCGGAAGACAAGCTGGCC
GTGGCGCGCGCCCGCAAGATCCAGCGCTTCCTGTCGCAACCCTTCCACGTGGCCGAGGTCTTCACCGGCTCGCCGGGCAA
GTACGTGCCGCTGAAGGAAACCATCCGTGGCTTCAAGATGATCGTGGCCGGCGAGTGTGACTCGCTCCCGGAACAGGCCT
TCTACATGGTCGGGACGATCGACGAAGCCTTCGAAAAGGCCAAGAAGATCCAATAA

Upstream 100 bases:

>100_bases
AAGAGCTTTCAGAGATTGTGAGCGGCGCGGCCGCGGTGGGCTGACGGCCCGACGCACCCGCAGACGCAACGCAAAGACTA
TTGATTGAAGGAACTGAAAA

Downstream 100 bases:

>100_bases
GCGGCGCAGACGGCGCTCGGGCGTCGTTGCCGTGCGCACTGGGCAGGAAGCCTGGTTCCGCGCGGCGCCTATCCGAACGC
CGCCTGCTTGCTTCTTGAAC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MANTQAAVGKIVQCIGAVVDVEFPRDQMPRVYDALKMEGSALTLEVQQQLGDGVVRTIALGSSDGLRRGLMVSNTGAAIT
VPVGKATLGRIMDVLGSPIDERGPVSAELSMPIHRKAPAYDELSPSQELLETGIKVIDLICPFAKGGKVGLFGGAGVGKT
VNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMSDSKVVVQEDLTQSKVAMVYGQMNEPPGNRLRVALTGLTIAES
FRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLTDPSPA
TTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQIDPNVVGEEHYNTTRAVQQVLQRYKELRDIIAILGMDELAPEDKLA
VARARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMIVAGECDSLPEQAFYMVGTIDEAFEKAKKIQ

Sequences:

>Translated_471_residues
MANTQAAVGKIVQCIGAVVDVEFPRDQMPRVYDALKMEGSALTLEVQQQLGDGVVRTIALGSSDGLRRGLMVSNTGAAIT
VPVGKATLGRIMDVLGSPIDERGPVSAELSMPIHRKAPAYDELSPSQELLETGIKVIDLICPFAKGGKVGLFGGAGVGKT
VNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMSDSKVVVQEDLTQSKVAMVYGQMNEPPGNRLRVALTGLTIAES
FRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLTDPSPA
TTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQIDPNVVGEEHYNTTRAVQQVLQRYKELRDIIAILGMDELAPEDKLA
VARARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMIVAGECDSLPEQAFYMVGTIDEAFEKAKKIQ
>Mature_470_residues
ANTQAAVGKIVQCIGAVVDVEFPRDQMPRVYDALKMEGSALTLEVQQQLGDGVVRTIALGSSDGLRRGLMVSNTGAAITV
PVGKATLGRIMDVLGSPIDERGPVSAELSMPIHRKAPAYDELSPSQELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTV
NMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMSDSKVVVQEDLTQSKVAMVYGQMNEPPGNRLRVALTGLTIAESF
RDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLTDPSPAT
TFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQIDPNVVGEEHYNTTRAVQQVLQRYKELRDIIAILGMDELAPEDKLAV
ARARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMIVAGECDSLPEQAFYMVGTIDEAFEKAKKIQ

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=468, Percent_Identity=69.6581196581197, Blast_Score=654, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=320, Percent_Identity=27.1875, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI50345984, Length=395, Percent_Identity=25.3164556962025, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4757810, Length=395, Percent_Identity=25.3164556962025, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI19913428, Length=433, Percent_Identity=24.9422632794457, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI19913426, Length=411, Percent_Identity=24.8175182481752, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1790170, Length=466, Percent_Identity=80.2575107296137, Blast_Score=751, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=313, Percent_Identity=31.3099041533546, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1790172, Length=315, Percent_Identity=25.0793650793651, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=474, Percent_Identity=66.8776371308017, Blast_Score=632, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=323, Percent_Identity=28.4829721362229, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71988080, Length=413, Percent_Identity=25.181598062954, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=413, Percent_Identity=25.181598062954, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=412, Percent_Identity=24.5145631067961, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17510931, Length=357, Percent_Identity=25.4901960784314, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988074, Length=356, Percent_Identity=23.876404494382, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322581, Length=464, Percent_Identity=65.0862068965517, Blast_Score=613, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319370, Length=398, Percent_Identity=26.3819095477387, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319603, Length=422, Percent_Identity=26.0663507109005, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6320016, Length=238, Percent_Identity=24.7899159663866, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24638766, Length=465, Percent_Identity=67.9569892473118, Blast_Score=637, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=466, Percent_Identity=64.5922746781116, Blast_Score=599, Evalue=1e-171,
Organism=Drosophila melanogaster, GI20129479, Length=318, Percent_Identity=28.9308176100629, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24583988, Length=350, Percent_Identity=26.2857142857143, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583986, Length=350, Percent_Identity=26.2857142857143, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583984, Length=350, Percent_Identity=26.2857142857143, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583992, Length=322, Percent_Identity=26.7080745341615, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24658560, Length=424, Percent_Identity=24.7641509433962, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281361666, Length=405, Percent_Identity=24.9382716049383, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24646341, Length=405, Percent_Identity=24.9382716049383, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17136796, Length=405, Percent_Identity=24.9382716049383, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24638768, Length=91, Percent_Identity=50.5494505494505, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50966; Mature: 50835

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTQAAVGKIVQCIGAVVDVEFPRDQMPRVYDALKMEGSALTLEVQQQLGDGVVRTIAL
CCCCHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHCCCCEEEEEEHHHHCCCCEEEEEE
GSSDGLRRGLMVSNTGAAITVPVGKATLGRIMDVLGSPIDERGPVSAELSMPIHRKAPAY
CCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCC
DELSPSQELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVF
CCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEE
AGVGERTREGNDFYHEMSDSKVVVQEDLTQSKVAMVYGQMNEPPGNRLRVALTGLTIAES
CCCCCCCCCCCHHHHHCCCCEEEEHHHCHHHHHHHEEECCCCCCCCEEEEEEECHHHHHH
FRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGS
HHHCCCEEEEEEECHHHEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
ITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQIDPNVV
CEEEEEEEECCCCCCCCCCCCEEECCCEEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCC
GEEHYNTTRAVQQVLQRYKELRDIIAILGMDELAPEDKLAVARARKIQRFLSQPFHVAEV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCEEEHE
FTGSPGKYVPLKETIRGFKMIVAGECDSLPEQAFYMVGTIDEAFEKAKKIQ
EECCCCCCCCHHHHHHHHEEEEECCCCCCCHHHHEEHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANTQAAVGKIVQCIGAVVDVEFPRDQMPRVYDALKMEGSALTLEVQQQLGDGVVRTIAL
CCCHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHCCCCEEEEEEHHHHCCCCEEEEEE
GSSDGLRRGLMVSNTGAAITVPVGKATLGRIMDVLGSPIDERGPVSAELSMPIHRKAPAY
CCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCC
DELSPSQELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVF
CCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEE
AGVGERTREGNDFYHEMSDSKVVVQEDLTQSKVAMVYGQMNEPPGNRLRVALTGLTIAES
CCCCCCCCCCCHHHHHCCCCEEEEHHHCHHHHHHHEEECCCCCCCCEEEEEEECHHHHHH
FRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGS
HHHCCCEEEEEEECHHHEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
ITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQIDPNVV
CEEEEEEEECCCCCCCCCCCCEEECCCEEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCC
GEEHYNTTRAVQQVLQRYKELRDIIAILGMDELAPEDKLAVARARKIQRFLSQPFHVAEV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCEEEHE
FTGSPGKYVPLKETIRGFKMIVAGECDSLPEQAFYMVGTIDEAFEKAKKIQ
EECCCCCCCCHHHHHHHHEEEEECCCCCCCHHHHEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA