Click here to switch to the map view.

The map label for this gene is sigK [H]

Identifier: 124265354

GI number: 124265354

Start: 170263

End: 170829

Strand: Direct

Name: sigK [H]

Synonym: Mpe_A0161

Alternate gene names: 124265354

Gene position: 170263-170829 (Clockwise)

Preceding gene: 124265353

Following gene: 124265355

Centisome position: 4.21

GC content: 70.19

Gene sequence:

>567_bases
ATGTCCAGCAGTCCCCCCCGCCGCACGGCCGATCCTTTCGACTACGAGTCGGCGCTCGAAGCCTGCGCCCGTGGCGAACG
CTTCGCGCTGCGGGCGCTCTACGAGCGCGAGGCGCGCTGGCTGCTCGGCGTGGCATTGCGCATCGTGCGGGACCGTGACA
TGGCGCACGACGTGCTGCAGGACGCCTTCCTGCAGGTCTGGCAGCGGGCGTCGAGCTACCAGCGCGCGCTCGGGTCGGCG
CGCGGCTGGATCTACACCGTGGTGCGCCATCGCGCGCTCGACGAGGTGCGCCGCGTGCGCCGCGAGACGCCGGTGGGCGA
CGAACTCGAAGCGCTGGCCGACCAGCATGCCGCGTCGAACGCAGTGCATGAGCTGCCGCATGCCGACGCGGCCTCGCTGT
CGCGTTGCATGGAGACGCTGGACGAGCGCAAGCGCGACTGCATCGTCTACGCCTTCGTCGAGGGCTACACCCACGAGCAG
ATCGCGCAGCAGACCGCCACGCCGGTCGGCACCGTCAAATCGTGGATCCGTCGCGGTCTGCTGTCGCTGAAGGAGTGCCT
GTCGTGA

Upstream 100 bases:

>100_bases
CATCGCGCCGCGCCTGCCGCGTTCCCCTGAATCCCACCATGCCCACCCACGCCTCGCCCTGCTGGTACGCAGCCTCGGCA
TGTGCTGACAGAATCCGCCC

Downstream 100 bases:

>100_bases
GCCTCGACGATCCGCACGAGCGCAGCGCCACCGCCGGCGAGTACGTGCTGGGCACGCTGGGCGCGTCCGAGCGTGCCGAG
TTCCAGCGTGCGCTGGGGGA

Product: sigma-70 region 2

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSSSPPRRTADPFDYESALEACARGERFALRALYEREARWLLGVALRIVRDRDMAHDVLQDAFLQVWQRASSYQRALGSA
RGWIYTVVRHRALDEVRRVRRETPVGDELEALADQHAASNAVHELPHADAASLSRCMETLDERKRDCIVYAFVEGYTHEQ
IAQQTATPVGTVKSWIRRGLLSLKECLS

Sequences:

>Translated_188_residues
MSSSPPRRTADPFDYESALEACARGERFALRALYEREARWLLGVALRIVRDRDMAHDVLQDAFLQVWQRASSYQRALGSA
RGWIYTVVRHRALDEVRRVRRETPVGDELEALADQHAASNAVHELPHADAASLSRCMETLDERKRDCIVYAFVEGYTHEQ
IAQQTATPVGTVKSWIRRGLLSLKECLS
>Mature_187_residues
SSSPPRRTADPFDYESALEACARGERFALRALYEREARWLLGVALRIVRDRDMAHDVLQDAFLQVWQRASSYQRALGSAR
GWIYTVVRHRALDEVRRVRRETPVGDELEALADQHAASNAVHELPHADAASLSRCMETLDERKRDCIVYAFVEGYTHEQI
AQQTATPVGTVKSWIRRGLLSLKECLS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 21410; Mature: 21279

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSPPRRTADPFDYESALEACARGERFALRALYEREARWLLGVALRIVRDRDMAHDVLQ
CCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAFLQVWQRASSYQRALGSARGWIYTVVRHRALDEVRRVRRETPVGDELEALADQHAASN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AVHELPHADAASLSRCMETLDERKRDCIVYAFVEGYTHEQIAQQTATPVGTVKSWIRRGL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHH
LSLKECLS
HHHHHHHC
>Mature Secondary Structure 
SSSPPRRTADPFDYESALEACARGERFALRALYEREARWLLGVALRIVRDRDMAHDVLQ
CCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAFLQVWQRASSYQRALGSARGWIYTVVRHRALDEVRRVRRETPVGDELEALADQHAASN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AVHELPHADAASLSRCMETLDERKRDCIVYAFVEGYTHEQIAQQTATPVGTVKSWIRRGL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHH
LSLKECLS
HHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA