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The map label for this gene is 124265333

Identifier: 124265333

GI number: 124265333

Start: 145726

End: 147861

Strand: Direct

Name: 124265333

Synonym: Mpe_A0140

Alternate gene names: NA

Gene position: 145726-147861 (Clockwise)

Preceding gene: 124265332

Following gene: 124265334

Centisome position: 3.6

GC content: 72.19

Gene sequence:

>2136_bases
ATGTTCTTCCCCTCCCTGCGTCCGCGCGCCGTCATCCCGCTGCGCCCGCTGTCGCGCCCGGGCCGGCTGTGGGCCGTGGT
CCTGGCGCTCGCCTGCCTGGCGAGCCTGCTGCTCGTCGCGCTGCCGGCGCAGGCCGATGACGCCGACGCGCGGCGCGCCG
AGAGCCCGTACTTCTTCGTCAAGAGCGACGACCCGAGCGTCGACCGCCTGCCGCTGAAGGCCACCGAGGTCGACGCGCGC
ATCGCCGGGCCGATCGCCGACGTCACGGTGACGCAGCGCTACCGCAACGAGGGCCAGCGTCCCATCGAGGCGCGCTATGT
CTTCCCCGGCTCCACGCAGGCCGCGGTGCACGCGATGACGGTGCGCGTCGGCCACCGCGTGATCGTCGCCGACATCCGCG
AGAAGCAGCGCGCCCGCATCGAGTTCGAGGCCGCCAAGCGCGAAGGCAAGACCGCCGCGCTGCTGGAGCAGGAGCGGCCC
AACGTGTTCTCGATGAACGTGGCCAACATCCTGCCGGGCGACGAGGTGGCGGTGGAGCTGCGCTACACCGAGCTGCTGCC
GCCCACCGAGGGCCGCTACCAGTTCGTGTTCCCCACCGTGGTGGGCCCGCGCTATCGCTCCCCCGCCAACAAGGTCGCAA
CCACTGAAGAGCAAGCAAACGGCACGGCAGCGCCGTCCGGCAGCTTCCCCGCCGTGCCCTACCTGCCCGCGGGCGAGGCG
TCGGACACCCGCTTCGACCTGCGCGTGGCCTTCGCCTCGCCGCTGCCGGTGAGCGGCCTGCGCTCCAGCTCCCACCAGAT
CGAGGTGGAAGGCGAAGGCAGCAACGGCGCGCGCGTCGCGCTGGGCGGTGACGCGGAGTCCTCCCGCCACAACGGCAACC
GCGATTTCATCCTCGACTACCGCCTCGCCGGTGACGGCATCGCCTCGGGCCTCACGCTGTTCCCGGGCGCGCCCGGCGAG
GAGAACTTCTTCCTCGCGATGGTGGAGCCGCCCCGGGCCATCGCCACCACGCAGATCAACCCGCGCGACTACGTGTTCGT
GGTCGACATCTCGGGTTCGATGCACGGCTACCCGCTCGACACCGCCAAGACGCTGCTGCGCCACCTGATCGGCGGGCTGC
GTCCCAGCGACACGTTCAACGTGCTGCTGTTCTCGGGCAGCAACCGCATGCTCAACGAGACCTCGGTGCCGGCCACGCAG
GCCAACGTCGCGCAGGCGCTGCGCACCATTGCGCAGATGGGCGGCAGCGGCAGCACCGAGATCGTGCCGGCGCTCAAGCG
CGTGGCCGCGCTGCCCAAGTCGCCCGACGTGTCGCGCAGCGTGATCGTGGTGACCGACGGCTACGTCACGGTGGAGAGCG
AGGTGTTCCAGCTCATCCGCAGGAACCTCGGCCAGACCAACGTGTTCGCGTTCGGCATCGGCAGCTCGGTCAACCGCCAT
CTCATCGAGGGCATTGCACGCGCCGGCCAGGGCGAGCCCTTCATCGTCACGCGGCCCGAGCAGGCTGCCGCGCAGGCCGA
GCGCCTGCGCCGCATGATCGACGCGCCGGTGCTCACGCAGGTGAAGGCGCGCTTCGAGGGCCTGGACACCTACGACGTGG
AACCCGAGCGCCTGCCTGACGTGCTGGGTGGCCGCCCGGTGCTGGTGTTCGGCAAGTGGCGCGGCGAGCCGCGCGGCCAG
CTCGTCGTCGAAGGCCAGGCGGCCCACGGCGCCTGGCAGGCGATGCTGCCGGTCGCCACGCCCGACGCGCAGGCCGTGGC
GCTGCGCCACCTGTGGGCGCGCCACCGCATCCAGTCGCTGTCGGACCAGGAGGCGCTGCAGGGCGGCGACACGCAGCGCG
AGGCCATCACCGCGCTGGGCCTGCGCTACAGCCTGCTCACGCAGTACACCAGCTTCATCGCCGTGGACCGCGTGGTGCGC
AACCCCGCCGGCGGCAGCACGCCGGTGGACCAGCCCTCGCCCCTGCCGCAGGGCGTGAGCAACCTGGCCATCGGCGCCGA
GGTGCCCAGCACGCCGGAGCCTTCGGCCTGGATCGCGCTGGGCGTGGTGCTGGTGCTGCTGGGTGCGGCGGCCTGGCACC
GCGGCGGATCTAGCGCCAAGCGCCTGTGGCGCAAGCCGCGGCGCCTGGTGCGGTGA

Upstream 100 bases:

>100_bases
GTCTTCACACACCCTCTCCCCAACTTCCTCGTCTTTTCTCACCCCCCGCGGAAGCTCCTCCCCGTGCCCGCCTCGCGGCA
CGTCGCCTCAGGAGCCCGCC

Downstream 100 bases:

>100_bases
GCGGGGACCTCAACCATGCATTCGCAACCCTATCGACTGCGTCTCACCGGCACGCCCGGCCTGGCCGCGCTGCCTGCCGG
GGCCTGGCTGGCGCTGCACG

Product: hypothetical protein

Products: NA

Alternate protein names: Von Willebrand Factor Type A Domain-Containing Protein; Vault Protein Inter-Alpha-Trypsin; Inter-Alpha-Trypsin Inhibitor Domain-Containing Protein; Vault Protein Inter-Alpha-Trypsin Domain Protein; Von Willebrand Factor Type A; Cell Wall Anchor Domain-Containing Protein; Vault Protein Inter-Alpha-Trypsin Domain-Containing Protein; Von Willebrand Factor Type A Domain Protein; LPXTG-Motif Cell Wall Anchor Domain-Containing Protein; Transmembrane Protein; LPXTG-Motif Cell Wall Anchor Domain Protein; Vault Protein Inter-Alpha-Trypsin Domain; Protein ContAining A Von Willebrand Factor Type A Domain; Inter-Alpha-Trypsin Inhibitor Domain Protein; Von Willebrand Factor

Number of amino acids: Translated: 711; Mature: 711

Protein sequence:

>711_residues
MFFPSLRPRAVIPLRPLSRPGRLWAVVLALACLASLLLVALPAQADDADARRAESPYFFVKSDDPSVDRLPLKATEVDAR
IAGPIADVTVTQRYRNEGQRPIEARYVFPGSTQAAVHAMTVRVGHRVIVADIREKQRARIEFEAAKREGKTAALLEQERP
NVFSMNVANILPGDEVAVELRYTELLPPTEGRYQFVFPTVVGPRYRSPANKVATTEEQANGTAAPSGSFPAVPYLPAGEA
SDTRFDLRVAFASPLPVSGLRSSSHQIEVEGEGSNGARVALGGDAESSRHNGNRDFILDYRLAGDGIASGLTLFPGAPGE
ENFFLAMVEPPRAIATTQINPRDYVFVVDISGSMHGYPLDTAKTLLRHLIGGLRPSDTFNVLLFSGSNRMLNETSVPATQ
ANVAQALRTIAQMGGSGSTEIVPALKRVAALPKSPDVSRSVIVVTDGYVTVESEVFQLIRRNLGQTNVFAFGIGSSVNRH
LIEGIARAGQGEPFIVTRPEQAAAQAERLRRMIDAPVLTQVKARFEGLDTYDVEPERLPDVLGGRPVLVFGKWRGEPRGQ
LVVEGQAAHGAWQAMLPVATPDAQAVALRHLWARHRIQSLSDQEALQGGDTQREAITALGLRYSLLTQYTSFIAVDRVVR
NPAGGSTPVDQPSPLPQGVSNLAIGAEVPSTPEPSAWIALGVVLVLLGAAAWHRGGSSAKRLWRKPRRLVR

Sequences:

>Translated_711_residues
MFFPSLRPRAVIPLRPLSRPGRLWAVVLALACLASLLLVALPAQADDADARRAESPYFFVKSDDPSVDRLPLKATEVDAR
IAGPIADVTVTQRYRNEGQRPIEARYVFPGSTQAAVHAMTVRVGHRVIVADIREKQRARIEFEAAKREGKTAALLEQERP
NVFSMNVANILPGDEVAVELRYTELLPPTEGRYQFVFPTVVGPRYRSPANKVATTEEQANGTAAPSGSFPAVPYLPAGEA
SDTRFDLRVAFASPLPVSGLRSSSHQIEVEGEGSNGARVALGGDAESSRHNGNRDFILDYRLAGDGIASGLTLFPGAPGE
ENFFLAMVEPPRAIATTQINPRDYVFVVDISGSMHGYPLDTAKTLLRHLIGGLRPSDTFNVLLFSGSNRMLNETSVPATQ
ANVAQALRTIAQMGGSGSTEIVPALKRVAALPKSPDVSRSVIVVTDGYVTVESEVFQLIRRNLGQTNVFAFGIGSSVNRH
LIEGIARAGQGEPFIVTRPEQAAAQAERLRRMIDAPVLTQVKARFEGLDTYDVEPERLPDVLGGRPVLVFGKWRGEPRGQ
LVVEGQAAHGAWQAMLPVATPDAQAVALRHLWARHRIQSLSDQEALQGGDTQREAITALGLRYSLLTQYTSFIAVDRVVR
NPAGGSTPVDQPSPLPQGVSNLAIGAEVPSTPEPSAWIALGVVLVLLGAAAWHRGGSSAKRLWRKPRRLVR
>Mature_711_residues
MFFPSLRPRAVIPLRPLSRPGRLWAVVLALACLASLLLVALPAQADDADARRAESPYFFVKSDDPSVDRLPLKATEVDAR
IAGPIADVTVTQRYRNEGQRPIEARYVFPGSTQAAVHAMTVRVGHRVIVADIREKQRARIEFEAAKREGKTAALLEQERP
NVFSMNVANILPGDEVAVELRYTELLPPTEGRYQFVFPTVVGPRYRSPANKVATTEEQANGTAAPSGSFPAVPYLPAGEA
SDTRFDLRVAFASPLPVSGLRSSSHQIEVEGEGSNGARVALGGDAESSRHNGNRDFILDYRLAGDGIASGLTLFPGAPGE
ENFFLAMVEPPRAIATTQINPRDYVFVVDISGSMHGYPLDTAKTLLRHLIGGLRPSDTFNVLLFSGSNRMLNETSVPATQ
ANVAQALRTIAQMGGSGSTEIVPALKRVAALPKSPDVSRSVIVVTDGYVTVESEVFQLIRRNLGQTNVFAFGIGSSVNRH
LIEGIARAGQGEPFIVTRPEQAAAQAERLRRMIDAPVLTQVKARFEGLDTYDVEPERLPDVLGGRPVLVFGKWRGEPRGQ
LVVEGQAAHGAWQAMLPVATPDAQAVALRHLWARHRIQSLSDQEALQGGDTQREAITALGLRYSLLTQYTSFIAVDRVVR
NPAGGSTPVDQPSPLPQGVSNLAIGAEVPSTPEPSAWIALGVVLVLLGAAAWHRGGSSAKRLWRKPRRLVR

Specific function: Unknown

COG id: COG2304

COG function: function code R; Uncharacterized protein containing a von Willebrand factor type A (vWA) domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI38195080, Length=630, Percent_Identity=26.984126984127, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI194306644, Length=630, Percent_Identity=26.984126984127, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI112789550, Length=600, Percent_Identity=23.6666666666667, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI38195082, Length=418, Percent_Identity=28.9473684210526, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI70778918, Length=651, Percent_Identity=22.1198156682028, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI38348336, Length=623, Percent_Identity=23.7560192616372, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI133925809, Length=596, Percent_Identity=22.6510067114094, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI31542984, Length=587, Percent_Identity=23.5093696763203, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI262050538, Length=587, Percent_Identity=23.5093696763203, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI210147462, Length=544, Percent_Identity=21.875, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI153945711, Length=331, Percent_Identity=24.4712990936556, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI153945780, Length=331, Percent_Identity=24.4712990936556, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI49355778, Length=331, Percent_Identity=24.4712990936556, Blast_Score=78, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 76848; Mature: 76848

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFPSLRPRAVIPLRPLSRPGRLWAVVLALACLASLLLVALPAQADDADARRAESPYFFV
CCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEE
KSDDPSVDRLPLKATEVDARIAGPIADVTVTQRYRNEGQRPIEARYVFPGSTQAAVHAMT
ECCCCCCCCCCCCHHCCCHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHEEEE
VRVGHRVIVADIREKQRARIEFEAAKREGKTAALLEQERPNVFSMNVANILPGDEVAVEL
EECCCEEEEEEHHHHHHHEEEEHHHHCCCCEEEHHHHCCCCEEEEEHHHCCCCCCEEEEE
RYTELLPPTEGRYQFVFPTVVGPRYRSPANKVATTEEQANGTAAPSGSFPAVPYLPAGEA
EEEECCCCCCCCEEEEEECCCCCCCCCCCHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
SDTRFDLRVAFASPLPVSGLRSSSHQIEVEGEGSNGARVALGGDAESSRHNGNRDFILDY
CCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCEEEEE
RLAGDGIASGLTLFPGAPGEENFFLAMVEPPRAIATTQINPRDYVFVVDISGSMHGYPLD
EECCCCHHCCCEECCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCCCCH
TAKTLLRHLIGGLRPSDTFNVLLFSGSNRMLNETSVPATQANVAQALRTIAQMGGSGSTE
HHHHHHHHHHCCCCCCCCEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCCH
IVPALKRVAALPKSPDVSRSVIVVTDGYVTVESEVFQLIRRNLGQTNVFAFGIGSSVNRH
HHHHHHHHHCCCCCCCCCCEEEEEECCEEEEHHHHHHHHHHHCCCCEEEEEECCCCHHHH
LIEGIARAGQGEPFIVTRPEQAAAQAERLRRMIDAPVLTQVKARFEGLDTYDVEPERLPD
HHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHH
VLGGRPVLVFGKWRGEPRGQLVVEGQAAHGAWQAMLPVATPDAQAVALRHLWARHRIQSL
HHCCCEEEEEEECCCCCCCEEEEECCCCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHC
SDQEALQGGDTQREAITALGLRYSLLTQYTSFIAVDRVVRNPAGGSTPVDQPSPLPQGVS
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
NLAIGAEVPSTPEPSAWIALGVVLVLLGAAAWHRGGSSAKRLWRKPRRLVR
HEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFFPSLRPRAVIPLRPLSRPGRLWAVVLALACLASLLLVALPAQADDADARRAESPYFFV
CCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEE
KSDDPSVDRLPLKATEVDARIAGPIADVTVTQRYRNEGQRPIEARYVFPGSTQAAVHAMT
ECCCCCCCCCCCCHHCCCHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHEEEE
VRVGHRVIVADIREKQRARIEFEAAKREGKTAALLEQERPNVFSMNVANILPGDEVAVEL
EECCCEEEEEEHHHHHHHEEEEHHHHCCCCEEEHHHHCCCCEEEEEHHHCCCCCCEEEEE
RYTELLPPTEGRYQFVFPTVVGPRYRSPANKVATTEEQANGTAAPSGSFPAVPYLPAGEA
EEEECCCCCCCCEEEEEECCCCCCCCCCCHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
SDTRFDLRVAFASPLPVSGLRSSSHQIEVEGEGSNGARVALGGDAESSRHNGNRDFILDY
CCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCEEEEE
RLAGDGIASGLTLFPGAPGEENFFLAMVEPPRAIATTQINPRDYVFVVDISGSMHGYPLD
EECCCCHHCCCEECCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCCCCH
TAKTLLRHLIGGLRPSDTFNVLLFSGSNRMLNETSVPATQANVAQALRTIAQMGGSGSTE
HHHHHHHHHHCCCCCCCCEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCCH
IVPALKRVAALPKSPDVSRSVIVVTDGYVTVESEVFQLIRRNLGQTNVFAFGIGSSVNRH
HHHHHHHHHCCCCCCCCCCEEEEEECCEEEEHHHHHHHHHHHCCCCEEEEEECCCCHHHH
LIEGIARAGQGEPFIVTRPEQAAAQAERLRRMIDAPVLTQVKARFEGLDTYDVEPERLPD
HHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHH
VLGGRPVLVFGKWRGEPRGQLVVEGQAAHGAWQAMLPVATPDAQAVALRHLWARHRIQSL
HHCCCEEEEEEECCCCCCCEEEEECCCCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHC
SDQEALQGGDTQREAITALGLRYSLLTQYTSFIAVDRVVRNPAGGSTPVDQPSPLPQGVS
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
NLAIGAEVPSTPEPSAWIALGVVLVLLGAAAWHRGGSSAKRLWRKPRRLVR
HEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA