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The map label for this gene is eriC [C]

Identifier: 124027722

GI number: 124027722

Start: 845090

End: 846949

Strand: Reverse

Name: eriC [C]

Synonym: Hbut_0846

Alternate gene names: 124027722

Gene position: 846949-845090 (Counterclockwise)

Preceding gene: 124027727

Following gene: 124027721

Centisome position: 50.8

GC content: 51.83

Gene sequence:

>1860_bases
ATGGCGGTAATAGCGATTCTGGCTAGGAAGCTTGACGAAGCTGTACGGGCTGTGCTAAAACACCTGGGCTATGTTGAACG
CTGGCTCCTCATAAGCATTGTTGCTGCTGTAGTTTCATCACTCGCCATAGGCTTGTTCTATGTGCTTCTAAGGCTTGTTC
TTGCGGGCGCAGCCTACATTCATGGCGTAGCTGGGCCGGAAATAGTTATGAAGATATCAGACTACTCCATAGTTGCGCTC
CTAGCTCGACACAAACCACTGATACCCGTTATACTCGGTGTCGGCGCGCTAGCTGCAAGCTTGATAGTCTACAAGTTTGA
GCCCGAGGCGGCTGGTGGCGGTACAGACGCGGCGGTATACGCGTACCACCATAGGGCCGGTATAATGAGGCCGAGGGTAG
CCATAGTAAAGGCGGTGGCATCGGCTATACTGCTAGGCACCGGCGGTAGTGCAGGGCCAGAGGGTCCCTCAATACAGATT
GGTGGTGCTGCAGGCTCCTCAATAGCAAAATACCTTGGCATGGGTGTTGTGGAGAGAAAGATAATGCTTGTAGCCGGCAT
GGCTGCGGCTCTATCATTCATCTTTCAGAGCCCCGTAGGATCAGCAATATTCGCCGTGGAAGTACTCTACATGAGGGATA
TGGAGCTAAATGCTTTGATACCAGCCCTTTTCGCGTCGATAATCTCGTACTCCCTATCCCTACACATCCTGGGCCCAGGG
TATAAGCTGCCATCACTCGCAATTGACAGTTTATCGAGGATGTATAGCTTGGATGTGCTAGCATCCTACATATTGCTAGG
TCTTTTCACTGCACCCTTTGCCTATATGTATGTCTACGTGTTCACGAGAACCAGGAGGGTCTTCGAGAAGCTCCATAGAG
AACATCGTATCCCCCAATGGATTGGCCCCGTCATTGGTGCGTTGCTCGTTGGTGTCATAGGCGCTTTTGTGCCCCATGTG
CTCGGTACTGGTGAGGAGTTACTCTCGTTGATGCTCGAAGGATTTCAGCAAGGCGAAATGCCGGGTCTAGTAAGGTTATT
CGGCGATAGCCTACTCTTGACTGCGCTGCTGCTGGCTATTCTAAAGATAGTAGTTACGTCCTTGACAGTCGGTAGTGGTG
GTAGTGGTGGGCTGCTAGCACCAGGCCTATTCGCCGGGGCTATGATAGGTGAAGTTTTTGGCCTCATAGTCCACGACTAC
ACCGGGATACCCCCAGGGGTCTATGCCTACCTCGGCATGGCGAGCCTCTTTGGTGCAGCTTCAAAGGTATCTGTTGGCCT
CTCATTCTTCGTGGCAGAGATAGGTGGTACACCAGCACTAGTCGTGCCAGCCCTCATATCCTCCCTAACGGCGTCGCTTG
CCCTTGGCAACGTCAGCATTGTTGAGTCACAGCTACCCCACAAGGTGCCCCCCGCTATATTTACCGTGGAGTCTCTCCTT
GAGATCCTCCGTGGCCAGAAGACATGTATAAAGGTTAGAGAGTTCCCGATAAGGCACATAACTGCTGCAAACTGGAACGA
AAAACTCAGAGACGTCGTTAAGAGGATGATAAGACAGAAGCTCCGCATAATGCCGGTCGTAGATGACTACGGGAGAATTG
TAGGTGTACTAGACCCTGGCTACATAGGGCTTGATCTCCGCTATGCCTTACGCTCGGAAGAGCTTGTCGCCGAGGTCTCC
CTAACACAGCCACCAATAGTCTACATTGATGACTGTATTGTTAGAGCGCTAGAGGAAATGGTGATATATGGTGCTGACTA
CGTGGGTTGTTGCAGGCCCCGGCTACAAGTATGCAGGCGTGATACTACTCGAAGACATTACCGATGCGCTCTTTCCATCA
ATACTCGAGGCAGCGCGTAG

Upstream 100 bases:

>100_bases
CCTGGCCACCCAGCCCTCCCAGTGGCGCGGGGGCTTAAGGAGAATACTCCTCTTATTCAACTCACCGCTCCAGCTAGCAT
TGATGGGGACGCGTAGAGTC

Downstream 100 bases:

>100_bases
AGGTAAGCGAACGTCGCACCGAGAAGTCGGAAGAGACTGGTAGAGCTAGATAGGCAAGGTTGAAGTCATAAACCCGTACA
CATCCTTCCTCATAGGTGGA

Product: hypothetical protein

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 618

Protein sequence:

>619_residues
MAVIAILARKLDEAVRAVLKHLGYVERWLLISIVAAVVSSLAIGLFYVLLRLVLAGAAYIHGVAGPEIVMKISDYSIVAL
LARHKPLIPVILGVGALAASLIVYKFEPEAAGGGTDAAVYAYHHRAGIMRPRVAIVKAVASAILLGTGGSAGPEGPSIQI
GGAAGSSIAKYLGMGVVERKIMLVAGMAAALSFIFQSPVGSAIFAVEVLYMRDMELNALIPALFASIISYSLSLHILGPG
YKLPSLAIDSLSRMYSLDVLASYILLGLFTAPFAYMYVYVFTRTRRVFEKLHREHRIPQWIGPVIGALLVGVIGAFVPHV
LGTGEELLSLMLEGFQQGEMPGLVRLFGDSLLLTALLLAILKIVVTSLTVGSGGSGGLLAPGLFAGAMIGEVFGLIVHDY
TGIPPGVYAYLGMASLFGAASKVSVGLSFFVAEIGGTPALVVPALISSLTASLALGNVSIVESQLPHKVPPAIFTVESLL
EILRGQKTCIKVREFPIRHITAANWNEKLRDVVKRMIRQKLRIMPVVDDYGRIVGVLDPGYIGLDLRYALRSEELVAEVS
LTQPPIVYIDDCIVRALEEMVIYGADYVGCCRPRLQVCRRDTTRRHYRCALSINTRGSA

Sequences:

>Translated_619_residues
MAVIAILARKLDEAVRAVLKHLGYVERWLLISIVAAVVSSLAIGLFYVLLRLVLAGAAYIHGVAGPEIVMKISDYSIVAL
LARHKPLIPVILGVGALAASLIVYKFEPEAAGGGTDAAVYAYHHRAGIMRPRVAIVKAVASAILLGTGGSAGPEGPSIQI
GGAAGSSIAKYLGMGVVERKIMLVAGMAAALSFIFQSPVGSAIFAVEVLYMRDMELNALIPALFASIISYSLSLHILGPG
YKLPSLAIDSLSRMYSLDVLASYILLGLFTAPFAYMYVYVFTRTRRVFEKLHREHRIPQWIGPVIGALLVGVIGAFVPHV
LGTGEELLSLMLEGFQQGEMPGLVRLFGDSLLLTALLLAILKIVVTSLTVGSGGSGGLLAPGLFAGAMIGEVFGLIVHDY
TGIPPGVYAYLGMASLFGAASKVSVGLSFFVAEIGGTPALVVPALISSLTASLALGNVSIVESQLPHKVPPAIFTVESLL
EILRGQKTCIKVREFPIRHITAANWNEKLRDVVKRMIRQKLRIMPVVDDYGRIVGVLDPGYIGLDLRYALRSEELVAEVS
LTQPPIVYIDDCIVRALEEMVIYGADYVGCCRPRLQVCRRDTTRRHYRCALSINTRGSA
>Mature_618_residues
AVIAILARKLDEAVRAVLKHLGYVERWLLISIVAAVVSSLAIGLFYVLLRLVLAGAAYIHGVAGPEIVMKISDYSIVALL
ARHKPLIPVILGVGALAASLIVYKFEPEAAGGGTDAAVYAYHHRAGIMRPRVAIVKAVASAILLGTGGSAGPEGPSIQIG
GAAGSSIAKYLGMGVVERKIMLVAGMAAALSFIFQSPVGSAIFAVEVLYMRDMELNALIPALFASIISYSLSLHILGPGY
KLPSLAIDSLSRMYSLDVLASYILLGLFTAPFAYMYVYVFTRTRRVFEKLHREHRIPQWIGPVIGALLVGVIGAFVPHVL
GTGEELLSLMLEGFQQGEMPGLVRLFGDSLLLTALLLAILKIVVTSLTVGSGGSGGLLAPGLFAGAMIGEVFGLIVHDYT
GIPPGVYAYLGMASLFGAASKVSVGLSFFVAEIGGTPALVVPALISSLTASLALGNVSIVESQLPHKVPPAIFTVESLLE
ILRGQKTCIKVREFPIRHITAANWNEKLRDVVKRMIRQKLRIMPVVDDYGRIVGVLDPGYIGLDLRYALRSEELVAEVSL
TQPPIVYIDDCIVRALEEMVIYGADYVGCCRPRLQVCRRDTTRRHYRCALSINTRGSA

Specific function: Selective chloride channel [C]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family [H]

Homologues:

Organism=Homo sapiens, GI153252026, Length=382, Percent_Identity=24.3455497382199, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786350, Length=366, Percent_Identity=26.5027322404372, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 66231; Mature: 66099

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVIAILARKLDEAVRAVLKHLGYVERWLLISIVAAVVSSLAIGLFYVLLRLVLAGAAYI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGVAGPEIVMKISDYSIVALLARHKPLIPVILGVGALAASLIVYKFEPEAAGGGTDAAVY
HCCCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHEE
AYHHRAGIMRPRVAIVKAVASAILLGTGGSAGPEGPSIQIGGAAGSSIAKYLGMGVVERK
EEHHHCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCEEECCCCHHHHHHHHCCHHHHHH
IMLVAGMAAALSFIFQSPVGSAIFAVEVLYMRDMELNALIPALFASIISYSLSLHILGPG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCC
YKLPSLAIDSLSRMYSLDVLASYILLGLFTAPFAYMYVYVFTRTRRVFEKLHREHRIPQW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IGPVIGALLVGVIGAFVPHVLGTGEELLSLMLEGFQQGEMPGLVRLFGDSLLLTALLLAI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LKIVVTSLTVGSGGSGGLLAPGLFAGAMIGEVFGLIVHDYTGIPPGVYAYLGMASLFGAA
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCH
SKVSVGLSFFVAEIGGTPALVVPALISSLTASLALGNVSIVESQLPHKVPPAIFTVESLL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHH
EILRGQKTCIKVREFPIRHITAANWNEKLRDVVKRMIRQKLRIMPVVDDYGRIVGVLDPG
HHHCCCHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
YIGLDLRYALRSEELVAEVSLTQPPIVYIDDCIVRALEEMVIYGADYVGCCRPRLQVCRR
EEEEEHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHH
DTTRRHYRCALSINTRGSA
HCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
AVIAILARKLDEAVRAVLKHLGYVERWLLISIVAAVVSSLAIGLFYVLLRLVLAGAAYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGVAGPEIVMKISDYSIVALLARHKPLIPVILGVGALAASLIVYKFEPEAAGGGTDAAVY
HCCCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHEE
AYHHRAGIMRPRVAIVKAVASAILLGTGGSAGPEGPSIQIGGAAGSSIAKYLGMGVVERK
EEHHHCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCEEECCCCHHHHHHHHCCHHHHHH
IMLVAGMAAALSFIFQSPVGSAIFAVEVLYMRDMELNALIPALFASIISYSLSLHILGPG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCC
YKLPSLAIDSLSRMYSLDVLASYILLGLFTAPFAYMYVYVFTRTRRVFEKLHREHRIPQW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IGPVIGALLVGVIGAFVPHVLGTGEELLSLMLEGFQQGEMPGLVRLFGDSLLLTALLLAI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LKIVVTSLTVGSGGSGGLLAPGLFAGAMIGEVFGLIVHDYTGIPPGVYAYLGMASLFGAA
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCH
SKVSVGLSFFVAEIGGTPALVVPALISSLTASLALGNVSIVESQLPHKVPPAIFTVESLL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHH
EILRGQKTCIKVREFPIRHITAANWNEKLRDVVKRMIRQKLRIMPVVDDYGRIVGVLDPG
HHHCCCHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
YIGLDLRYALRSEELVAEVSLTQPPIVYIDDCIVRALEEMVIYGADYVGCCRPRLQVCRR
EEEEEHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHH
DTTRRHYRCALSINTRGSA
HCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]