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The map label for this gene is 124027717

Identifier: 124027717

GI number: 124027717

Start: 840138

End: 840809

Strand: Reverse

Name: 124027717

Synonym: Hbut_0841

Alternate gene names: NA

Gene position: 840809-840138 (Counterclockwise)

Preceding gene: 124027719

Following gene: 124027716

Centisome position: 50.43

GC content: 52.68

Gene sequence:

>672_bases
TTGCCCGAGTGTAGTAGGCCGCGGGTCTACGTTGACGAGAGGGAGAAGGCTAGCCCCATTCCCCGCTTATTGAGGGAGAT
GGGTGCAGCCGTAATCTACACTGTTGCAGGTGTCGGCGATTACATTGTTTCGGATAGGGTTGCATTCGAGAGGAAGACCA
TGCACGACCTTGCAGCAAGCCTTTTCGATGGCAGGCTCTACGACCAGGCTAGAAGGCTGAGCGAGCACTATGAAGTCCCA
ATAATACTCGTTGAGGGTGACCCAGCAGAGCTGGAAAGGGTTACCTCGCGTGCATTGCAGGTTAAGCTTGCCCTATTGGC
GATAAGCCTCGACTATAGTGTAAGGATCGTCTGGAGCAGTGGTCCGGAAGAGTCAGCAAAAATAATCTATAGTGTTGCGT
GTCGTGAGCAGGCTCTGAAGCAGAGGCCCGTGGTTATACATAGGAAGCCGAGGCTCGAGAAGCTGTGGATGCAGCAGCTA
TATGTTGTCCAGAGCCTGCCCGGCATAGGGCCTAGGCTCGCGGAGAGGCTCCTTGAAAAATTCGGCAGTATAGAGGCTAT
ATGCAGAGCATCAATAGTTGAGCTTGAGAAGGTTCTTGGCTATGAGAGAGCCGTAAAGGTGTACCGCGTAATACATGCTC
CATATACGTCTTCCAAAGCAGAGCGGGAGTAG

Upstream 100 bases:

>100_bases
TCGGCCTCTAGCGTATTCCTCACAGCCCCTCCAGGGCATCCTAGCTCCATGGTTTACAAGCTATTAACGGGTTGTGCAGC
AGCTAAACGGGGTACAGCTC

Downstream 100 bases:

>100_bases
CAGCAATCCTGACGCCCATGGAGCGGGAGCCGGGTGGGGCAACAAGAGAGAGCCCAGTACTTTATAACCCGGGGACCGTT
ACTCGCCCCTTCACCGGGTG

Product: ERCC4-type nuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MPECSRPRVYVDEREKASPIPRLLREMGAAVIYTVAGVGDYIVSDRVAFERKTMHDLAASLFDGRLYDQARRLSEHYEVP
IILVEGDPAELERVTSRALQVKLALLAISLDYSVRIVWSSGPEESAKIIYSVACREQALKQRPVVIHRKPRLEKLWMQQL
YVVQSLPGIGPRLAERLLEKFGSIEAICRASIVELEKVLGYERAVKVYRVIHAPYTSSKAERE

Sequences:

>Translated_223_residues
MPECSRPRVYVDEREKASPIPRLLREMGAAVIYTVAGVGDYIVSDRVAFERKTMHDLAASLFDGRLYDQARRLSEHYEVP
IILVEGDPAELERVTSRALQVKLALLAISLDYSVRIVWSSGPEESAKIIYSVACREQALKQRPVVIHRKPRLEKLWMQQL
YVVQSLPGIGPRLAERLLEKFGSIEAICRASIVELEKVLGYERAVKVYRVIHAPYTSSKAERE
>Mature_222_residues
PECSRPRVYVDEREKASPIPRLLREMGAAVIYTVAGVGDYIVSDRVAFERKTMHDLAASLFDGRLYDQARRLSEHYEVPI
ILVEGDPAELERVTSRALQVKLALLAISLDYSVRIVWSSGPEESAKIIYSVACREQALKQRPVVIHRKPRLEKLWMQQLY
VVQSLPGIGPRLAERLLEKFGSIEAICRASIVELEKVLGYERAVKVYRVIHAPYTSSKAERE

Specific function: Unknown

COG id: COG1948

COG function: function code L; ERCC4-type nuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4885217, Length=223, Percent_Identity=26.9058295964126, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17532461, Length=138, Percent_Identity=34.0579710144928, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325235, Length=163, Percent_Identity=30.0613496932515, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17933560, Length=235, Percent_Identity=29.7872340425532, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR020819
- InterPro:   IPR006166
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR011335
- InterPro:   IPR010994 [H]

Pfam domain/function: PF00270 DEAD; PF02732 ERCC4; PF00271 Helicase_C; PF00633 HHH [H]

EC number: =3.6.4.13 [H]

Molecular weight: Translated: 25364; Mature: 25233

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPECSRPRVYVDEREKASPIPRLLREMGAAVIYTVAGVGDYIVSDRVAFERKTMHDLAAS
CCCCCCCCEEECCCCCCCHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LFDGRLYDQARRLSEHYEVPIILVEGDPAELERVTSRALQVKLALLAISLDYSVRIVWSS
HHCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHEEEECCEEEEEECC
GPEESAKIIYSVACREQALKQRPVVIHRKPRLEKLWMQQLYVVQSLPGIGPRLAERLLEK
CCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FGSIEAICRASIVELEKVLGYERAVKVYRVIHAPYTSSKAERE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PECSRPRVYVDEREKASPIPRLLREMGAAVIYTVAGVGDYIVSDRVAFERKTMHDLAAS
CCCCCCCEEECCCCCCCHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LFDGRLYDQARRLSEHYEVPIILVEGDPAELERVTSRALQVKLALLAISLDYSVRIVWSS
HHCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHEEEECCEEEEEECC
GPEESAKIIYSVACREQALKQRPVVIHRKPRLEKLWMQQLYVVQSLPGIGPRLAERLLEK
CCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FGSIEAICRASIVELEKVLGYERAVKVYRVIHAPYTSSKAERE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]