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The map label for this gene is cdd [H]

Identifier: 124027705

GI number: 124027705

Start: 824613

End: 825065

Strand: Reverse

Name: cdd [H]

Synonym: Hbut_0828

Alternate gene names: 124027705

Gene position: 825065-824613 (Counterclockwise)

Preceding gene: 124027709

Following gene: 124027704

Centisome position: 49.49

GC content: 55.63

Gene sequence:

>453_bases
TTGGCTAGCTTGGGGGTGGATCTAGAGGAGCTATTCCAGAGGGCCAAGCAAGTCATAGGTAACAGCTATGCCCCCTACAG
TGGGGTCCATGTAGCAGCAGTTGTTCTAGCAGACGATGGAACAGTCTACCTGGGCGTCAATGTCGAGAATGTAAGTTACG
GCTTAACAATCTGTGCTGAGAGGGCGGCAGTAGCGGCAATGATTACAGCTGGCCGCCGCAGGATAAAGGCAGTGGCAATA
GTGTCAGATACAACCTTACCACTACCGCCTTGTGGAGCCTGCCGCCAGGTGATAGCAGAGTTTGCGGACGATGACACTGT
GATCGCTTCACGCTCGCTAGTAACCGGTGAGACAAGGGTGTGGAGGCTACGTGACCTCCTACCAGATCCCGTCAAGCCTG
AAGCAATAAGGCTCAGCCGCCGCTCCCAAGCCCCCTCTCAGCACAGCCCGTAG

Upstream 100 bases:

>100_bases
TGGGCGTACGTGTTTGAGGAATGTGCCTCTAGGGTCTTGAGTTGTTAGCTGAGAAGCTATGCTATGCATAGCATGCCCCC
GGCTCCAGGGGTGAGAGTCC

Downstream 100 bases:

>100_bases
GGGGCTAAGCACAGGCCAGCATCATCACAGCCAACTGGTCCGGCAGGGATATAAGCCTCTGAGAGCCAGTACATACTCGT
TTAGCGTAGCTGGAGTCGAT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MASLGVDLEELFQRAKQVIGNSYAPYSGVHVAAVVLADDGTVYLGVNVENVSYGLTICAERAAVAAMITAGRRRIKAVAI
VSDTTLPLPPCGACRQVIAEFADDDTVIASRSLVTGETRVWRLRDLLPDPVKPEAIRLSRRSQAPSQHSP

Sequences:

>Translated_150_residues
MASLGVDLEELFQRAKQVIGNSYAPYSGVHVAAVVLADDGTVYLGVNVENVSYGLTICAERAAVAAMITAGRRRIKAVAI
VSDTTLPLPPCGACRQVIAEFADDDTVIASRSLVTGETRVWRLRDLLPDPVKPEAIRLSRRSQAPSQHSP
>Mature_149_residues
ASLGVDLEELFQRAKQVIGNSYAPYSGVHVAAVVLADDGTVYLGVNVENVSYGLTICAERAAVAAMITAGRRRIKAVAIV
SDTTLPLPPCGACRQVIAEFADDDTVIASRSLVTGETRVWRLRDLLPDPVKPEAIRLSRRSQAPSQHSP

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=134, Percent_Identity=33.5820895522388, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551074, Length=141, Percent_Identity=34.7517730496454, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540514, Length=135, Percent_Identity=35.5555555555556, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323274, Length=132, Percent_Identity=34.8484848484849, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582741, Length=104, Percent_Identity=37.5, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920920, Length=135, Percent_Identity=36.2962962962963, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24582744, Length=109, Percent_Identity=38.5321100917431, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 16072; Mature: 15940

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLGVDLEELFQRAKQVIGNSYAPYSGVHVAAVVLADDGTVYLGVNVENVSYGLTICAE
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEEEEEECCCEEHHHHHHH
RAAVAAMITAGRRRIKAVAIVSDTTLPLPPCGACRQVIAEFADDDTVIASRSLVTGETRV
HHHHHHHHHHCHHHEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEECCCEECCCHHH
WRLRDLLPDPVKPEAIRLSRRSQAPSQHSP
HHHHHCCCCCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ASLGVDLEELFQRAKQVIGNSYAPYSGVHVAAVVLADDGTVYLGVNVENVSYGLTICAE
CCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEEEEEECCCEEHHHHHHH
RAAVAAMITAGRRRIKAVAIVSDTTLPLPPCGACRQVIAEFADDDTVIASRSLVTGETRV
HHHHHHHHHHCHHHEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEECCCEECCCHHH
WRLRDLLPDPVKPEAIRLSRRSQAPSQHSP
HHHHHCCCCCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8349569 [H]