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The map label for this gene is htpX [H]

Identifier: 124027651

GI number: 124027651

Start: 767563

End: 768666

Strand: Direct

Name: htpX [H]

Synonym: Hbut_0773

Alternate gene names: 124027651

Gene position: 767563-768666 (Clockwise)

Preceding gene: 124027650

Following gene: 124027652

Centisome position: 46.04

GC content: 57.7

Gene sequence:

>1104_bases
TTGTTCCTCCTGGTATGGGACCCGCTAACATTCACCGTGCTCGTGCTTCTCTATGCGGCTGGGTTCCTCCTGCTCCAGCT
GCTAGCTATGCGTGTAGCACCCCGCGTAGCTGGGTTCATATCTAGCCGGGTGAGCCTCTACACCGCGATGCTCATCACGG
CCGGCCTCATTGTTGGTGGTGGCCTCATAGCGATCTATGCTATCTACAGCCTAGCTGCGAGTTATGGCTATAGCCTGCCT
ATTGGGTTCCTGCTGGCATTCCTCATCGTAGCTAACCTGATGAGCTACCTGCTGGCGCCATACATGATCAATGCTGTTTA
CAGGGCTAAGCCTGACCCGGAGCTCCAGCGCATCGTGGACGAGGTTGCTTCGAGGGCTGGTGTTAAGCCGCCAAAGGCTG
TTATCGTTGAAGGTCCGCCAAACGCATTCGCCTATGGCAACTTCCTTACTGGCCGCTACATCGCCGTGTCGAGGAGCCTC
TACGAGATTCTGCCCCGCAACGAGCTCGAGGCCGTGGTAGGCCACGAGATTGGCCACCACAGGCACCGCGACGTAGTCAT
AATCATGTTGCTGGGCCTTGTGCCAAGCATACTCTACTACATGGGCGTATGGCTTATACGTATAGGGCTGTGGAGCGGCG
CCTACCGTAGCCGCCGCGAGGGCAACGGCGGCCTGGCCCTTGTCGCTGTGGGCGCGCTGAGCGTGCTGCTAAGCTTCATC
ATGCAGGTAGCAGTGCTAACGTTTAGCAGGCTACGCGAGTACTACGCTGACGCCCATGGAGCTATCGTTGCCGGCGCGAG
GCCCATGCAGCGTGCCCTGGCTAGGCTCCACCTCTACTATCAGGGCCGTAGGAGGGAAGAGCTAGAGAAGAGCAGTCTGA
AGGCACTCTTCATCTACGCACTTGTAGAGGCTGCAGCATCACCATTCTACAGCTACACTGGCAGCAGCTGGTCCTGGAGA
GGAGACATCGACAGCATCGTCGAGAGGCTGAAGAGGATGGAGGTCAATCCTGCAGAGGAACTGTTCAGCGACCACCCACC
GATACCCAAGAGGCTAAGGTTCCTTGACAACCTCGAGCAGGCCCTAGGCAAAGCAAGAGTCTAA

Upstream 100 bases:

>100_bases
TATCCTGCCCCTCGTGGAAGACCTTATTACCTGGGTTTAGAGTTTGCAGCACTCACTCTAGGCGAGAAGCTGTATGGGAT
AGGTATGGGGTGGTGAGTAC

Downstream 100 bases:

>100_bases
ACAGCCAAGTTTTCACGACACAAAGCCACACTGCATGTAATATTTTACAGTGTGGTCTTCAATCCAGCCCCTCAGCAGAG
TGGAAACATTCCCCTCCACG

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MFLLVWDPLTFTVLVLLYAAGFLLLQLLAMRVAPRVAGFISSRVSLYTAMLITAGLIVGGGLIAIYAIYSLAASYGYSLP
IGFLLAFLIVANLMSYLLAPYMINAVYRAKPDPELQRIVDEVASRAGVKPPKAVIVEGPPNAFAYGNFLTGRYIAVSRSL
YEILPRNELEAVVGHEIGHHRHRDVVIIMLLGLVPSILYYMGVWLIRIGLWSGAYRSRREGNGGLALVAVGALSVLLSFI
MQVAVLTFSRLREYYADAHGAIVAGARPMQRALARLHLYYQGRRREELEKSSLKALFIYALVEAAASPFYSYTGSSWSWR
GDIDSIVERLKRMEVNPAEELFSDHPPIPKRLRFLDNLEQALGKARV

Sequences:

>Translated_367_residues
MFLLVWDPLTFTVLVLLYAAGFLLLQLLAMRVAPRVAGFISSRVSLYTAMLITAGLIVGGGLIAIYAIYSLAASYGYSLP
IGFLLAFLIVANLMSYLLAPYMINAVYRAKPDPELQRIVDEVASRAGVKPPKAVIVEGPPNAFAYGNFLTGRYIAVSRSL
YEILPRNELEAVVGHEIGHHRHRDVVIIMLLGLVPSILYYMGVWLIRIGLWSGAYRSRREGNGGLALVAVGALSVLLSFI
MQVAVLTFSRLREYYADAHGAIVAGARPMQRALARLHLYYQGRRREELEKSSLKALFIYALVEAAASPFYSYTGSSWSWR
GDIDSIVERLKRMEVNPAEELFSDHPPIPKRLRFLDNLEQALGKARV
>Mature_367_residues
MFLLVWDPLTFTVLVLLYAAGFLLLQLLAMRVAPRVAGFISSRVSLYTAMLITAGLIVGGGLIAIYAIYSLAASYGYSLP
IGFLLAFLIVANLMSYLLAPYMINAVYRAKPDPELQRIVDEVASRAGVKPPKAVIVEGPPNAFAYGNFLTGRYIAVSRSL
YEILPRNELEAVVGHEIGHHRHRDVVIIMLLGLVPSILYYMGVWLIRIGLWSGAYRSRREGNGGLALVAVGALSVLLSFI
MQVAVLTFSRLREYYADAHGAIVAGARPMQRALARLHLYYQGRRREELEKSSLKALFIYALVEAAASPFYSYTGSSWSWR
GDIDSIVERLKRMEVNPAEELFSDHPPIPKRLRFLDNLEQALGKARV

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=292, Percent_Identity=29.7945205479452, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 40768; Mature: 40768

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLLVWDPLTFTVLVLLYAAGFLLLQLLAMRVAPRVAGFISSRVSLYTAMLITAGLIVGG
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLIAIYAIYSLAASYGYSLPIGFLLAFLIVANLMSYLLAPYMINAVYRAKPDPELQRIVD
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EVASRAGVKPPKAVIVEGPPNAFAYGNFLTGRYIAVSRSLYEILPRNELEAVVGHEIGHH
HHHHHCCCCCCCEEEEECCCCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
RHRDVVIIMLLGLVPSILYYMGVWLIRIGLWSGAYRSRREGNGGLALVAVGALSVLLSFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
MQVAVLTFSRLREYYADAHGAIVAGARPMQRALARLHLYYQGRRREELEKSSLKALFIYA
HHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LVEAAASPFYSYTGSSWSWRGDIDSIVERLKRMEVNPAEELFSDHPPIPKRLRFLDNLEQ
HHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHH
ALGKARV
HHHCCCC
>Mature Secondary Structure
MFLLVWDPLTFTVLVLLYAAGFLLLQLLAMRVAPRVAGFISSRVSLYTAMLITAGLIVGG
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLIAIYAIYSLAASYGYSLPIGFLLAFLIVANLMSYLLAPYMINAVYRAKPDPELQRIVD
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EVASRAGVKPPKAVIVEGPPNAFAYGNFLTGRYIAVSRSLYEILPRNELEAVVGHEIGHH
HHHHHCCCCCCCEEEEECCCCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
RHRDVVIIMLLGLVPSILYYMGVWLIRIGLWSGAYRSRREGNGGLALVAVGALSVLLSFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
MQVAVLTFSRLREYYADAHGAIVAGARPMQRALARLHLYYQGRRREELEKSSLKALFIYA
HHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LVEAAASPFYSYTGSSWSWRGDIDSIVERLKRMEVNPAEELFSDHPPIPKRLRFLDNLEQ
HHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHH
ALGKARV
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA