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The map label for this gene is metE [H]

Identifier: 124027602

GI number: 124027602

Start: 711349

End: 712323

Strand: Direct

Name: metE [H]

Synonym: Hbut_0723

Alternate gene names: 124027602

Gene position: 711349-712323 (Clockwise)

Preceding gene: 124027601

Following gene: 124027603

Centisome position: 42.67

GC content: 62.15

Gene sequence:

>975_bases
ATGGCTGTGGACGTGTTTGTGCTTGGCGGCTACTCGCGCGGCATTGGTGCACGGAAGGTTTTGAGGGAGTTTGAACGCGG
TGGCGTGGGCTGGGGCGAGGCCGAGGCTGTTATCGGGCTTGAGGAGGCAATGCTTGTCGGTGTTCAGGCTGGTGCTGGGC
TGACCTACGTGTCTGACCCTGCTCTGGCGTGGCACGACCTGCTCCGGCCCTTCGTTGAGGCCTGGCGTGGCGTTGCTGTG
GGTGGTCTCGCGAGGTTCTTCGACAACAACTTCTTCTACCGTGTCCCGGTGTTTACGGGTAAGCCCGATCCGAAGTACTA
TGTGCTCGCTAAGCGTGCAGTATTCCTCTCAAAGATTGCCCCCCGCGGTGCCGGCGTGAAGGTCTTCATGCCCGGGCCGG
TGACCTTCGCAGCTCTCTCCGATACCAGCGTGTTCGGCGGCATGGAGGAGGCTGCAAGGGAGATAGCACGCATCCTCGGC
GAAGAGGCCAGGAGGGCCCTGGAGGCCGGCGCCTCCGTGGTGGAGGTCGCCGAGCCGTTGCTAGGCGATATCGATGCCAG
GCCGGAGCACGCCGGGCTCCTCGTGGACCTCCTCTCCAAGTACTTCCCCGACCCCTCAAAGCTCATCGTATCAATCTACT
ACCACCCGCCCAGCAAGGAGGTAGCAAAGGAGCTAGCAGTGCTAAAGGCACAGTACCTCGCGCTAGACTACGCTGATAGG
CCGGAGACCTTCCGCGAGGCAGTAAAGATCGCCTGCCCCGAGGGCCTAGCTGTGGGTGCCGTGGATGCCCGTAGCATCTA
TCTGGAGCCTGTGGAGAGGGTGGAGAAGGCCCTGCAGACAGCAAAGGAGCTATGCAGCCCGGATAGGCTAGCACTAACAA
CGACAGCACCACTAGACCTCATACCACAGCAGCACGCCATCGCGAAGACCAGGCACCTAGGCCACCTCGCGAGGAGGCTC
GAGGAGGGAGCCTAG

Upstream 100 bases:

>100_bases
CCTGCCCTGCTGGGGGGCTGATTGGTTGTGTGTAACCCTTTTTTAGCTGGTTGTCTTGGCGTGTTGCGGGTGAGGCTTGA
TAGCTGGTTGGTAGGGGTGG

Downstream 100 bases:

>100_bases
GCAGCCACTACCCCGCCGCCATCCCCACATCCATGCACCAGTGCCACTGCATAGTAGAGCCATCGTGTACAGGCTTGGGG
GTGTACAGCAAAGCTTATAC

Product: methionine synthase II (cobalamin-independent)

Products: NA

Alternate protein names: Methionine synthase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MAVDVFVLGGYSRGIGARKVLREFERGGVGWGEAEAVIGLEEAMLVGVQAGAGLTYVSDPALAWHDLLRPFVEAWRGVAV
GGLARFFDNNFFYRVPVFTGKPDPKYYVLAKRAVFLSKIAPRGAGVKVFMPGPVTFAALSDTSVFGGMEEAAREIARILG
EEARRALEAGASVVEVAEPLLGDIDARPEHAGLLVDLLSKYFPDPSKLIVSIYYHPPSKEVAKELAVLKAQYLALDYADR
PETFREAVKIACPEGLAVGAVDARSIYLEPVERVEKALQTAKELCSPDRLALTTTAPLDLIPQQHAIAKTRHLGHLARRL
EEGA

Sequences:

>Translated_324_residues
MAVDVFVLGGYSRGIGARKVLREFERGGVGWGEAEAVIGLEEAMLVGVQAGAGLTYVSDPALAWHDLLRPFVEAWRGVAV
GGLARFFDNNFFYRVPVFTGKPDPKYYVLAKRAVFLSKIAPRGAGVKVFMPGPVTFAALSDTSVFGGMEEAAREIARILG
EEARRALEAGASVVEVAEPLLGDIDARPEHAGLLVDLLSKYFPDPSKLIVSIYYHPPSKEVAKELAVLKAQYLALDYADR
PETFREAVKIACPEGLAVGAVDARSIYLEPVERVEKALQTAKELCSPDRLALTTTAPLDLIPQQHAIAKTRHLGHLARRL
EEGA
>Mature_323_residues
AVDVFVLGGYSRGIGARKVLREFERGGVGWGEAEAVIGLEEAMLVGVQAGAGLTYVSDPALAWHDLLRPFVEAWRGVAVG
GLARFFDNNFFYRVPVFTGKPDPKYYVLAKRAVFLSKIAPRGAGVKVFMPGPVTFAALSDTSVFGGMEEAAREIARILGE
EARRALEAGASVVEVAEPLLGDIDARPEHAGLLVDLLSKYFPDPSKLIVSIYYHPPSKEVAKELAVLKAQYLALDYADRP
ETFREAVKIACPEGLAVGAVDARSIYLEPVERVEKALQTAKELCSPDRLALTTTAPLDLIPQQHAIAKTRHLGHLARRLE
EGA

Specific function: Catalyzes the transfer of a methyl group from methylcobalamin and methylcobinamide to homocysteine resulting in methionine formation [H]

COG id: COG0620

COG function: function code E; Methionine synthase II (cobalamin-independent)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the vitamin-B12 independent methionine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022921
- InterPro:   IPR002629 [H]

Pfam domain/function: PF01717 Meth_synt_2 [H]

EC number: NA

Molecular weight: Translated: 35109; Mature: 34978

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVDVFVLGGYSRGIGARKVLREFERGGVGWGEAEAVIGLEEAMLVGVQAGAGLTYVSDP
CEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHEEHHHHHHEEEECCCCCEEECCC
ALAWHDLLRPFVEAWRGVAVGGLARFFDNNFFYRVPVFTGKPDPKYYVLAKRAVFLSKIA
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHC
PRGAGVKVFMPGPVTFAALSDTSVFGGMEEAAREIARILGEEARRALEAGASVVEVAEPL
CCCCCEEEEECCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LGDIDARPEHAGLLVDLLSKYFPDPSKLIVSIYYHPPSKEVAKELAVLKAQYLALDYADR
HCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
PETFREAVKIACPEGLAVGAVDARSIYLEPVERVEKALQTAKELCSPDRLALTTTAPLDL
CHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHH
IPQQHAIAKTRHLGHLARRLEEGA
CCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVDVFVLGGYSRGIGARKVLREFERGGVGWGEAEAVIGLEEAMLVGVQAGAGLTYVSDP
EEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHEEHHHHHHEEEECCCCCEEECCC
ALAWHDLLRPFVEAWRGVAVGGLARFFDNNFFYRVPVFTGKPDPKYYVLAKRAVFLSKIA
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHC
PRGAGVKVFMPGPVTFAALSDTSVFGGMEEAAREIARILGEEARRALEAGASVVEVAEPL
CCCCCEEEEECCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LGDIDARPEHAGLLVDLLSKYFPDPSKLIVSIYYHPPSKEVAKELAVLKAQYLALDYADR
HCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
PETFREAVKIACPEGLAVGAVDARSIYLEPVERVEKALQTAKELCSPDRLALTTTAPLDL
CHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHH
IPQQHAIAKTRHLGHLARRLEEGA
CCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA