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The map label for this gene is cobU [H]

Identifier: 124025725

GI number: 124025725

Start: 944283

End: 944840

Strand: Direct

Name: cobU [H]

Synonym: NATL1_10181

Alternate gene names: 124025725

Gene position: 944283-944840 (Clockwise)

Preceding gene: 124025723

Following gene: 124025726

Centisome position: 50.64

GC content: 36.2

Gene sequence:

>558_bases
ATGATTACACCATTAGAAAAAAACTATAAAGGACTTATATCAATTACTGGACCGACAAGAAGTGGAAAAAGTCAATTGGC
AGAATTTTTAATCAAGAAACAACAATCCGTCACATATATAGCAACATCTAAACCAAGACCAAATGATCCAGATTGGCAAC
AAAGGATTGACCTCCACAGGAAGAGAAGACCTGATCGATGGAAGTTAATTGAGCATCCTAAGGATATCTGCAAAGCAATT
GAATCGATCAGTGAAAATGGATCAATATTAATAGATTCAATAGGTGGCTTAGTAGAGCATCACCTAGAGGATGACGATAC
TCAATGGGAAATATTCCAAGATAAATTACTTAATTGTTTTACAGATGATAATTTGCTAATCGTTTTTGTTTCAGAGGAGG
TTGGTTGGGGAATTGTTCCTGCAACACCAATAGGCCATTTATTTCGTGAACGTCATAGCACGTTAACCTCATTGCTTAGT
TGTCGTTCAAAAAAAAGGTTGCTTGCTATCAATGGGATTGCAATTGATTTAGATCAAATTGGCGAGCTCATACCATGA

Upstream 100 bases:

>100_bases
ATTGAATATGTATTATACATTTCGATGTCAACTTTAATTTTTGGCTATATCGATATAATATAAAAAAACACTATTAATAG
ATAACCCAATTGCTCAACAT

Downstream 100 bases:

>100_bases
ATTCATTAAATCGAACAAGACCTCGTGTCTCATTATTTGAACCAAGAATTCCACAGAACACTGGAACAATTGGTAGAACA
TGCTTAGCCTTTAATATGTC

Product: putative cobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MITPLEKNYKGLISITGPTRSGKSQLAEFLIKKQQSVTYIATSKPRPNDPDWQQRIDLHRKRRPDRWKLIEHPKDICKAI
ESISENGSILIDSIGGLVEHHLEDDDTQWEIFQDKLLNCFTDDNLLIVFVSEEVGWGIVPATPIGHLFRERHSTLTSLLS
CRSKKRLLAINGIAIDLDQIGELIP

Sequences:

>Translated_185_residues
MITPLEKNYKGLISITGPTRSGKSQLAEFLIKKQQSVTYIATSKPRPNDPDWQQRIDLHRKRRPDRWKLIEHPKDICKAI
ESISENGSILIDSIGGLVEHHLEDDDTQWEIFQDKLLNCFTDDNLLIVFVSEEVGWGIVPATPIGHLFRERHSTLTSLLS
CRSKKRLLAINGIAIDLDQIGELIP
>Mature_185_residues
MITPLEKNYKGLISITGPTRSGKSQLAEFLIKKQQSVTYIATSKPRPNDPDWQQRIDLHRKRRPDRWKLIEHPKDICKAI
ESISENGSILIDSIGGLVEHHLEDDDTQWEIFQDKLLNCFTDDNLLIVFVSEEVGWGIVPATPIGHLFRERHSTLTSLLS
CRSKKRLLAINGIAIDLDQIGELIP

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=28.7292817679558, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21059; Mature: 21059

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITPLEKNYKGLISITGPTRSGKSQLAEFLIKKQQSVTYIATSKPRPNDPDWQQRIDLHR
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHH
KRRPDRWKLIEHPKDICKAIESISENGSILIDSIGGLVEHHLEDDDTQWEIFQDKLLNCF
HCCCCHHHHHCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHC
TDDNLLIVFVSEEVGWGIVPATPIGHLFRERHSTLTSLLSCRSKKRLLAINGIAIDLDQI
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEECHHHH
GELIP
CCCCC
>Mature Secondary Structure
MITPLEKNYKGLISITGPTRSGKSQLAEFLIKKQQSVTYIATSKPRPNDPDWQQRIDLHR
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHH
KRRPDRWKLIEHPKDICKAIESISENGSILIDSIGGLVEHHLEDDDTQWEIFQDKLLNCF
HCCCCHHHHHCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHC
TDDNLLIVFVSEEVGWGIVPATPIGHLFRERHSTLTSLLSCRSKKRLLAINGIAIDLDQI
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEECHHHH
GELIP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]