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The map label for this gene is dnaJ2 [H]

Identifier: 124025693

GI number: 124025693

Start: 905609

End: 906526

Strand: Direct

Name: dnaJ2 [H]

Synonym: NATL1_09861

Alternate gene names: 124025693

Gene position: 905609-906526 (Clockwise)

Preceding gene: 124025692

Following gene: 124025694

Centisome position: 48.57

GC content: 34.1

Gene sequence:

>918_bases
ATGACTACTACCGTTGATCCTAATTATTGGTCTCTATTAGGAGTCTCTCCAGAATGTGATTCTAATGAGCTTAAATCCGC
CTTTAGGAAAGAGGCAAGAAAGTGGCACCCCGATTTAAATAAAAATGATGTCAATGCAGAGGAAAGATTTAAATTAATTA
ATGAAGCCTATGCGATTCTTAGCGATCCAAAAAAGAGAAGGGAATGGGAGAAACAAAATAATAAACATAAAGATATCTTT
GATAATAGATTCCCAAACTATGAGGAATATATAGATCTTGTATTAGGAATTAAAACAGATCTAAAAAGTGAAAGTGATGA
TCAATATTCAGAACATTCTGAAGATGAATATGAAAACTTTGAACAAACTAATTTTAATGAATATGTTCCCACAACTAGTG
AACCAGCACCACCTCCAACTTTAATTTATGAAGATCAAGAATCAATTGTAGAAATCACACCAGATCAAGCTCTTTATGGG
TCTTCAGTTGAAATCCAGTTACAAGACGGCACTCTAGTTGAGGTTTTAACTCCGCCATTTGCAGGTGATGGATGGAGATT
ACGAATAGAAGGTGCTGCAATAGGTTGTCGAGATCATTTTGTACAATTAAAAGTACAAACAGAAGATGGTCTAAGAATTG
ATGGATTAAGAGTTACGTATCGTCTTGAATTGTTTCCACATGATGCTTTATTGGGATGTGCTGTAGATATTCCAACTTTA
AATGGATCTGTGACATTACAAGTTCCTCCTAATTCATCTACAGGGAGATTATTAAGACTTAGAGGACGTGGATTGGAATA
CGAAGAATATCGTGGTGATCAAATCGTTGAAATAATTATTGTGTTACCAGATAATTTAAGTGATTCTGAACTTGCATTAT
ATCAGCGTCTAAATGAAATATCTATGGAGAATTATTAG

Upstream 100 bases:

>100_bases
GACGACTACTGGGATGATGATCCTTGGGATTATTCTCAAGGACGTCAAAATAGAAATGGTGATAATAATTATGGGAGAAG
GGATTTAGATCCTTGGGATA

Downstream 100 bases:

>100_bases
AATTATATTGTTTATTCAATTTATCGATTTATAATCGGATTGGTTATTTATTTATTATGTTAGTTCATGTCCTTTTGTAT
GAAGCGGGGACTGAAAGTGA

Product: DnaJ2 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTTTVDPNYWSLLGVSPECDSNELKSAFRKEARKWHPDLNKNDVNAEERFKLINEAYAILSDPKKRREWEKQNNKHKDIF
DNRFPNYEEYIDLVLGIKTDLKSESDDQYSEHSEDEYENFEQTNFNEYVPTTSEPAPPPTLIYEDQESIVEITPDQALYG
SSVEIQLQDGTLVEVLTPPFAGDGWRLRIEGAAIGCRDHFVQLKVQTEDGLRIDGLRVTYRLELFPHDALLGCAVDIPTL
NGSVTLQVPPNSSTGRLLRLRGRGLEYEEYRGDQIVEIIIVLPDNLSDSELALYQRLNEISMENY

Sequences:

>Translated_305_residues
MTTTVDPNYWSLLGVSPECDSNELKSAFRKEARKWHPDLNKNDVNAEERFKLINEAYAILSDPKKRREWEKQNNKHKDIF
DNRFPNYEEYIDLVLGIKTDLKSESDDQYSEHSEDEYENFEQTNFNEYVPTTSEPAPPPTLIYEDQESIVEITPDQALYG
SSVEIQLQDGTLVEVLTPPFAGDGWRLRIEGAAIGCRDHFVQLKVQTEDGLRIDGLRVTYRLELFPHDALLGCAVDIPTL
NGSVTLQVPPNSSTGRLLRLRGRGLEYEEYRGDQIVEIIIVLPDNLSDSELALYQRLNEISMENY
>Mature_304_residues
TTTVDPNYWSLLGVSPECDSNELKSAFRKEARKWHPDLNKNDVNAEERFKLINEAYAILSDPKKRREWEKQNNKHKDIFD
NRFPNYEEYIDLVLGIKTDLKSESDDQYSEHSEDEYENFEQTNFNEYVPTTSEPAPPPTLIYEDQESIVEITPDQALYGS
SVEIQLQDGTLVEVLTPPFAGDGWRLRIEGAAIGCRDHFVQLKVQTEDGLRIDGLRVTYRLELFPHDALLGCAVDIPTLN
GSVTLQVPPNSSTGRLLRLRGRGLEYEEYRGDQIVEIIIVLPDNLSDSELALYQRLNEISMENY

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI56549115, Length=59, Percent_Identity=54.2372881355932, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI201862518, Length=59, Percent_Identity=54.2372881355932, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI201862587, Length=59, Percent_Identity=54.2372881355932, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787235, Length=307, Percent_Identity=27.0358306188925, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786197, Length=64, Percent_Identity=40.625, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554644, Length=63, Percent_Identity=49.2063492063492, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322194, Length=92, Percent_Identity=40.2173913043478, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320888, Length=91, Percent_Identity=32.967032967033, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24654066, Length=112, Percent_Identity=34.8214285714286, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24654070, Length=112, Percent_Identity=34.8214285714286, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24654068, Length=112, Percent_Identity=34.8214285714286, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24654072, Length=112, Percent_Identity=34.8214285714286, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C [H]

EC number: NA

Molecular weight: Translated: 35035; Mature: 34904

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTVDPNYWSLLGVSPECDSNELKSAFRKEARKWHPDLNKNDVNAEERFKLINEAYAIL
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
SDPKKRREWEKQNNKHKDIFDNRFPNYEEYIDLVLGIKTDLKSESDDQYSEHSEDEYENF
CCCHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHCCHHCCCCCCCHHHHCCCHHHHHH
EQTNFNEYVPTTSEPAPPPTLIYEDQESIVEITPDQALYGSSVEIQLQDGTLVEVLTPPF
HHCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCEEEEEECCCCEEEEECCCC
AGDGWRLRIEGAAIGCRDHFVQLKVQTEDGLRIDGLRVTYRLELFPHDALLGCAVDIPTL
CCCCEEEEECCEEECCCEEEEEEEEECCCCCEECCEEEEEEEEECCCCCEEEEEEECCCC
NGSVTLQVPPNSSTGRLLRLRGRGLEYEEYRGDQIVEIIIVLPDNLSDSELALYQRLNEI
CCEEEEEECCCCCCCCEEEEECCCCCHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
SMENY
HCCCC
>Mature Secondary Structure 
TTTVDPNYWSLLGVSPECDSNELKSAFRKEARKWHPDLNKNDVNAEERFKLINEAYAIL
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
SDPKKRREWEKQNNKHKDIFDNRFPNYEEYIDLVLGIKTDLKSESDDQYSEHSEDEYENF
CCCHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHCCHHCCCCCCCHHHHCCCHHHHHH
EQTNFNEYVPTTSEPAPPPTLIYEDQESIVEITPDQALYGSSVEIQLQDGTLVEVLTPPF
HHCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCEEEEEECCCCEEEEECCCC
AGDGWRLRIEGAAIGCRDHFVQLKVQTEDGLRIDGLRVTYRLELFPHDALLGCAVDIPTL
CCCCEEEEECCEEECCCEEEEEEEEECCCCCEECCEEEEEEEEECCCCCEEEEEEECCCC
NGSVTLQVPPNSSTGRLLRLRGRGLEYEEYRGDQIVEIIIVLPDNLSDSELALYQRLNEI
CCEEEEEECCCCCCCCEEEEECCCCCHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
SMENY
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9240461; 8003021; 7811295 [H]