Click here to switch to the map view.

The map label for this gene is neuA [H]

Identifier: 124025581

GI number: 124025581

Start: 812053

End: 812739

Strand: Direct

Name: neuA [H]

Synonym: NATL1_08741

Alternate gene names: 124025581

Gene position: 812053-812739 (Clockwise)

Preceding gene: 124025580

Following gene: 124025582

Centisome position: 43.55

GC content: 28.53

Gene sequence:

>687_bases
TTGAAGAGCTTTAATGCTAGTGAAAAATACGTTTCAATAGTTCCTGTGAGGAAAGGCTCGAAAGGATTAAAAAACAAAAA
TTTAAGAGAGCTTAATGGAGTTCCTTTATATTTGATCGCTGTAAATCAGGCACTTAGATTAACAAATAAATGTATACTCT
CTACTGATATAGAAGAGATATTTAATAATAAACCTCCAAGAAATTGTTATATTCATAAGCGTAGAAAAGAATTATGCCAA
GATTCAACTAGGATGAATCAAGTAATAAATAATATAATAAATGAAATGCATTTAATAAATTCGGATGTTCTTCTTCTTCA
AGCCACATCGCCATTAAGAAAGGATTCAGATATACAAAATTGCATGAAATTATTCTCTAAAAAAAAATATTCAATGCTGC
TAAGTGTTAACAAGGCAAATTCTGATATCTTGAAACATGGAACAGTTGATAAATCTGGTTTTTTTAGAGGACTAAGAGAT
ACGAAAGATTGTTTTGCTAATAGGCAGGATCTTCCAACCCTATTTAAACCAAACGGAAGTATTTATATTTTCAACACAAA
AGAATTTATTAAATCAAATGATTTTCCAATAAATTCAATCGGAATATATGAGATGCCAAGAGAAAGATCTATAGACATTG
ATAATGAATCAGATTTTGAAAAAGTCTCTACATTTATGAATATTTAG

Upstream 100 bases:

>100_bases
ACCACAAGTCATAAAGGCTTTGGGAGTGGCAACTCGAGAAAAAAGTTTTTAAAATTCATCAATTCTGATAAGATATGGAA
TCAAAGTACTCAAAAAAGCT

Downstream 100 bases:

>100_bases
TTTATAGTAAAATATCTATAAAATAGAATTGAAATGAGAATTATAGGAAGATTGGATGTAAAGAATAATCATGTTATAAA
AGGGATTCACTTGGAAGGTC

Product: hypothetical protein

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKSFNASEKYVSIVPVRKGSKGLKNKNLRELNGVPLYLIAVNQALRLTNKCILSTDIEEIFNNKPPRNCYIHKRRKELCQ
DSTRMNQVINNIINEMHLINSDVLLLQATSPLRKDSDIQNCMKLFSKKKYSMLLSVNKANSDILKHGTVDKSGFFRGLRD
TKDCFANRQDLPTLFKPNGSIYIFNTKEFIKSNDFPINSIGIYEMPRERSIDIDNESDFEKVSTFMNI

Sequences:

>Translated_228_residues
MKSFNASEKYVSIVPVRKGSKGLKNKNLRELNGVPLYLIAVNQALRLTNKCILSTDIEEIFNNKPPRNCYIHKRRKELCQ
DSTRMNQVINNIINEMHLINSDVLLLQATSPLRKDSDIQNCMKLFSKKKYSMLLSVNKANSDILKHGTVDKSGFFRGLRD
TKDCFANRQDLPTLFKPNGSIYIFNTKEFIKSNDFPINSIGIYEMPRERSIDIDNESDFEKVSTFMNI
>Mature_228_residues
MKSFNASEKYVSIVPVRKGSKGLKNKNLRELNGVPLYLIAVNQALRLTNKCILSTDIEEIFNNKPPRNCYIHKRRKELCQ
DSTRMNQVINNIINEMHLINSDVLLLQATSPLRKDSDIQNCMKLFSKKKYSMLLSVNKANSDILKHGTVDKSGFFRGLRD
TKDCFANRQDLPTLFKPNGSIYIFNTKEFIKSNDFPINSIGIYEMPRERSIDIDNESDFEKVSTFMNI

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=221, Percent_Identity=28.0542986425339, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 26279; Mature: 26279

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFNASEKYVSIVPVRKGSKGLKNKNLRELNGVPLYLIAVNQALRLTNKCILSTDIEEI
CCCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCEEEEEHHHHHHHHHHHHHHCCHHHH
FNNKPPRNCYIHKRRKELCQDSTRMNQVINNIINEMHLINSDVLLLQATSPLRKDSDIQN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHH
CMKLFSKKKYSMLLSVNKANSDILKHGTVDKSGFFRGLRDTKDCFANRQDLPTLFKPNGS
HHHHHHCCHHEEEEEECCCCCHHHHCCCCCHHHHHHCCCHHHHHHCCCCCCCCEECCCCC
IYIFNTKEFIKSNDFPINSIGIYEMPRERSIDIDNESDFEKVSTFMNI
EEEEECHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKSFNASEKYVSIVPVRKGSKGLKNKNLRELNGVPLYLIAVNQALRLTNKCILSTDIEEI
CCCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCEEEEEHHHHHHHHHHHHHHCCHHHH
FNNKPPRNCYIHKRRKELCQDSTRMNQVINNIINEMHLINSDVLLLQATSPLRKDSDIQN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHH
CMKLFSKKKYSMLLSVNKANSDILKHGTVDKSGFFRGLRDTKDCFANRQDLPTLFKPNGS
HHHHHHCCHHEEEEEECCCCCHHHHCCCCCHHHHHHCCCHHHHHHCCCCCCCCEECCCCC
IYIFNTKEFIKSNDFPINSIGIYEMPRERSIDIDNESDFEKVSTFMNI
EEEEECHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1398032; 7830552; 8113198; 8045888; 10710307 [H]