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The map label for this gene is tsf

Identifier: 124025497

GI number: 124025497

Start: 721457

End: 722113

Strand: Direct

Name: tsf

Synonym: NATL1_07901

Alternate gene names: 124025497

Gene position: 721457-722113 (Clockwise)

Preceding gene: 124025496

Following gene: 124025498

Centisome position: 38.69

GC content: 39.12

Gene sequence:

>657_bases
ATGGCGGAAATAACAGCTAAACTCGTTAAAGAACTGCGAGATAAGACATCTGCAGGAATGATGGATTGTAAAAAAGCCCT
TATTGAAAATAAGGGTGATATGGATAAGTCTATTGAGTGGTTAAGACAAAAAGGCATTGCCAGCGCTGAAAAGAAATCAG
GTAGAGTTGCTGCTGAGGGCGCTGTAGGAAGTTACATTCATACAGGTTCTCGTGTAGGTGTTCTTCTGGAGCTGAACTGC
GAGACTGATTTTGTTGCTAGAGGTGATTTATTCCAAGGCCTTTTGAGAGACTTATCAATGCAAGTGGCCGCTTGTCCAAG
TGTTGAATATGTAAGTGTTGATCAAATTCCAGAATCAATTGCCAACAAAGAGAAAGAAATAGAAATGGGAAGAGATGACC
TCTCTGGTAAGCCTGATCAAATAAAAGCTAAAATCGTTGAAGGAAGAATAGGTAAGAGATTGAAAGAAATGGCTCTTTTA
GAACAGCCATTCATAAAAGATAGTTCAATAAATGTTGAAGAGTTGGTAAAACAAGTTGCTGGAAAAATTGGCGAAAATAT
AAGAGTTCGTAGATTTACCAGATATATACTTGGAGAGGGGATTGAGGTTCAAGGACCTGACTTCGCAGAAGAGGTCGCAT
CTATGACTTTAGGTTGA

Upstream 100 bases:

>100_bases
GCCGATGCTATCAATGAAGGGAGACATGGACCCAATGAGTAGTTAGCATATTTATTTAATAAATTCTTAACTTACCTTTT
TCTCACTACCCCAAAATAAA

Downstream 100 bases:

>100_bases
TCTTGTCTGAAAATAAGCATTTATTTGATTCTAATTTTGATCCTTTAGATCAAATAAGTCTTCTTAAAGAAAAATGTAAT
AATATATCTCCTCATTTATA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MAEITAKLVKELRDKTSAGMMDCKKALIENKGDMDKSIEWLRQKGIASAEKKSGRVAAEGAVGSYIHTGSRVGVLLELNC
ETDFVARGDLFQGLLRDLSMQVAACPSVEYVSVDQIPESIANKEKEIEMGRDDLSGKPDQIKAKIVEGRIGKRLKEMALL
EQPFIKDSSINVEELVKQVAGKIGENIRVRRFTRYILGEGIEVQGPDFAEEVASMTLG

Sequences:

>Translated_218_residues
MAEITAKLVKELRDKTSAGMMDCKKALIENKGDMDKSIEWLRQKGIASAEKKSGRVAAEGAVGSYIHTGSRVGVLLELNC
ETDFVARGDLFQGLLRDLSMQVAACPSVEYVSVDQIPESIANKEKEIEMGRDDLSGKPDQIKAKIVEGRIGKRLKEMALL
EQPFIKDSSINVEELVKQVAGKIGENIRVRRFTRYILGEGIEVQGPDFAEEVASMTLG
>Mature_217_residues
AEITAKLVKELRDKTSAGMMDCKKALIENKGDMDKSIEWLRQKGIASAEKKSGRVAAEGAVGSYIHTGSRVGVLLELNCE
TDFVARGDLFQGLLRDLSMQVAACPSVEYVSVDQIPESIANKEKEIEMGRDDLSGKPDQIKAKIVEGRIGKRLKEMALLE
QPFIKDSSINVEELVKQVAGKIGENIRVRRFTRYILGEGIEVQGPDFAEEVASMTLG

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Escherichia coli, GI1786366, Length=94, Percent_Identity=54.2553191489362, Blast_Score=101, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17561440, Length=214, Percent_Identity=29.4392523364486, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_PROM1 (A2C1I8)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014613.1
- ProteinModelPortal:   A2C1I8
- SMR:   A2C1I8
- STRING:   A2C1I8
- GeneID:   4779979
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_07901
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   NVEYVSI
- ProtClustDB:   PRK12332
- BioCyc:   PMAR167555:NATL1_07901-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 23959; Mature: 23828

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEITAKLVKELRDKTSAGMMDCKKALIENKGDMDKSIEWLRQKGIASAEKKSGRVAAEG
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHCCCEEECC
AVGSYIHTGSRVGVLLELNCETDFVARGDLFQGLLRDLSMQVAACPSVEYVSVDQIPESI
CCHHHHCCCCCEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHH
ANKEKEIEMGRDDLSGKPDQIKAKIVEGRIGKRLKEMALLEQPFIKDSSINVEELVKQVA
HCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
GKIGENIRVRRFTRYILGEGIEVQGPDFAEEVASMTLG
HHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
AEITAKLVKELRDKTSAGMMDCKKALIENKGDMDKSIEWLRQKGIASAEKKSGRVAAEG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHCCCEEECC
AVGSYIHTGSRVGVLLELNCETDFVARGDLFQGLLRDLSMQVAACPSVEYVSVDQIPESI
CCHHHHCCCCCEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHH
ANKEKEIEMGRDDLSGKPDQIKAKIVEGRIGKRLKEMALLEQPFIKDSSINVEELVKQVA
HCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
GKIGENIRVRRFTRYILGEGIEVQGPDFAEEVASMTLG
HHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA