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The map label for this gene is pqqL [C]

Identifier: 124025489

GI number: 124025489

Start: 714222

End: 715475

Strand: Reverse

Name: pqqL [C]

Synonym: NATL1_07821

Alternate gene names: 124025489

Gene position: 715475-714222 (Counterclockwise)

Preceding gene: 229000868

Following gene: 124025488

Centisome position: 38.37

GC content: 31.98

Gene sequence:

>1254_bases
ATGTGCTTTAAGAAATTTAGAATGAAAGTAAAACATTGGTCATTATCTAATGGTGCTACATGTGTTGTGGCTGATATAGA
AGATTCAACGTTGACATGTATTGACTTTTGGTGCAAAGGGGGAAGTTTATGTGAAATGAAAGGTGAAGAAGGTATGGCAC
ATTTCTTAGAGCACATGATATTTAAAGGGAGCAAAAACCTTAAAGAAGGTGAATTCGATTTAAAAATTGAATCTCTTGGT
GGAAGTAGTAATGCAGCGACTGGGTTGGACGATGTTCACTATCACGTTCTGGTGCCCCGTGAAAAAATAGAAGAAGGACT
AAAATTAATATTAGAATTATTATTATTTCCTAAAATTGAACAAGATGCCTTTGAAATGGAAAAAGAAGTAGTTTTAGAGG
AAATCGCACAAAATATTGATCAGCCAGATGAAATTATTTATATGAAATTGCTAAAGGGATGTTTAACACCACATAGATAT
TCGAAACCAATACTAGGTGATGAAACAACTGTTAAAAATATAAATCCAAAACAAATGAAACTATTCCACAAGAATCATTA
TGTAGGTAAAAACTGTACACTATGTATAGCAGGAGATTTGCCTAACGAAGTTCAATCAATAATTAATAATAGTAAATTGA
AGGAATTAAAAACAATCTCAAAGGAGACCGCAATAAGTAATACAATTACTTTTAACAAAGGCTATACAAAAAAAACTATT
CCAAGGCTTGAGGGAGGAAGAATATTGAAAGCTTGGAAACTTCCCCCTGCAAAAGAGCAGATCTTAATTTTAGGAGCAGA
AATTGCTGCCACAATGTTATGCGAAGGTAAAAGTAGTCTTATTGTTAAGGAATTAAGAGAAGAAAAACGTATTATTGAAT
CAATAGATATAGATTTACAAATCCTTGAAGAGGGTGGATTAATTCTTCTTGATGTCAGTTGTCCAGAGGAAAACCTTAAA
ATTGTCGAAAGTGATCTCAATAACATCCTCAAAGAATTAACTAGAGATTTAGTTACTAATAAAGATTTAGAGCGTGCAAA
AAAATTAGTCGTTAATAATATTTATTTTGGTTTAGAGTTGAGCTCTCAAATCGCCTCAACATTAGGGAATCAAGCTCTAT
GGGGGCGCCACAATTCAATCCTAAAATCAATAGATGATATTTCATATTGGACAACAAAACGATTAAATGAATTAATATTT
CCATTATTTGATCCAGAAAATGCTTTTACATTAATTGCTGAACCTGAGAAATAA

Upstream 100 bases:

>100_bases
TAAATATGAAATCAATCTTTTACAATTAAAGACATTTAGAATCAATTGATTTTAAATTTCGAAATCTTATTATCATATAT
TAATATAGCACAATGATTAA

Downstream 100 bases:

>100_bases
ATATGAACATAATTCTGGACAAACTAGATAGCAAAAATATAATGTCAGCCAAGCTATGGATAGAGGATGGCAGTAGGAAT
GATCCAAAAGATAAAAAAGG

Product: Zn-dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MCFKKFRMKVKHWSLSNGATCVVADIEDSTLTCIDFWCKGGSLCEMKGEEGMAHFLEHMIFKGSKNLKEGEFDLKIESLG
GSSNAATGLDDVHYHVLVPREKIEEGLKLILELLLFPKIEQDAFEMEKEVVLEEIAQNIDQPDEIIYMKLLKGCLTPHRY
SKPILGDETTVKNINPKQMKLFHKNHYVGKNCTLCIAGDLPNEVQSIINNSKLKELKTISKETAISNTITFNKGYTKKTI
PRLEGGRILKAWKLPPAKEQILILGAEIAATMLCEGKSSLIVKELREEKRIIESIDIDLQILEEGGLILLDVSCPEENLK
IVESDLNNILKELTRDLVTNKDLERAKKLVVNNIYFGLELSSQIASTLGNQALWGRHNSILKSIDDISYWTTKRLNELIF
PLFDPENAFTLIAEPEK

Sequences:

>Translated_417_residues
MCFKKFRMKVKHWSLSNGATCVVADIEDSTLTCIDFWCKGGSLCEMKGEEGMAHFLEHMIFKGSKNLKEGEFDLKIESLG
GSSNAATGLDDVHYHVLVPREKIEEGLKLILELLLFPKIEQDAFEMEKEVVLEEIAQNIDQPDEIIYMKLLKGCLTPHRY
SKPILGDETTVKNINPKQMKLFHKNHYVGKNCTLCIAGDLPNEVQSIINNSKLKELKTISKETAISNTITFNKGYTKKTI
PRLEGGRILKAWKLPPAKEQILILGAEIAATMLCEGKSSLIVKELREEKRIIESIDIDLQILEEGGLILLDVSCPEENLK
IVESDLNNILKELTRDLVTNKDLERAKKLVVNNIYFGLELSSQIASTLGNQALWGRHNSILKSIDDISYWTTKRLNELIF
PLFDPENAFTLIAEPEK
>Mature_417_residues
MCFKKFRMKVKHWSLSNGATCVVADIEDSTLTCIDFWCKGGSLCEMKGEEGMAHFLEHMIFKGSKNLKEGEFDLKIESLG
GSSNAATGLDDVHYHVLVPREKIEEGLKLILELLLFPKIEQDAFEMEKEVVLEEIAQNIDQPDEIIYMKLLKGCLTPHRY
SKPILGDETTVKNINPKQMKLFHKNHYVGKNCTLCIAGDLPNEVQSIINNSKLKELKTISKETAISNTITFNKGYTKKTI
PRLEGGRILKAWKLPPAKEQILILGAEIAATMLCEGKSSLIVKELREEKRIIESIDIDLQILEEGGLILLDVSCPEENLK
IVESDLNNILKELTRDLVTNKDLERAKKLVVNNIYFGLELSSQIASTLGNQALWGRHNSILKSIDDISYWTTKRLNELIF
PLFDPENAFTLIAEPEK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=179, Percent_Identity=27.3743016759777, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI156071450, Length=273, Percent_Identity=26.007326007326, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI46593007, Length=182, Percent_Identity=22.5274725274725, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI156071452, Length=264, Percent_Identity=26.8939393939394, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1787770, Length=179, Percent_Identity=26.8156424581006, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=208, Percent_Identity=27.8846153846154, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI115533970, Length=332, Percent_Identity=26.5060240963855, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994338, Length=198, Percent_Identity=30.8080808080808, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25146563, Length=198, Percent_Identity=30.8080808080808, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25146566, Length=198, Percent_Identity=30.8080808080808, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566665, Length=198, Percent_Identity=30.8080808080808, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17553678, Length=235, Percent_Identity=22.9787234042553, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=189, Percent_Identity=26.4550264550265, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641429, Length=191, Percent_Identity=31.9371727748691, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357875, Length=189, Percent_Identity=23.8095238095238, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24646943, Length=189, Percent_Identity=23.8095238095238, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47131; Mature: 47131

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCFKKFRMKVKHWSLSNGATCVVADIEDSTLTCIDFWCKGGSLCEMKGEEGMAHFLEHMI
CCCHHHHHHHHEEECCCCCEEEEEECCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHH
FKGSKNLKEGEFDLKIESLGGSSNAATGLDDVHYHVLVPREKIEEGLKLILELLLFPKIE
HCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCC
QDAFEMEKEVVLEEIAQNIDQPDEIIYMKLLKGCLTPHRYSKPILGDETTVKNINPKQMK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
LFHKNHYVGKNCTLCIAGDLPNEVQSIINNSKLKELKTISKETAISNTITFNKGYTKKTI
HHHHCCCCCCCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCCCHHCC
PRLEGGRILKAWKLPPAKEQILILGAEIAATMLCEGKSSLIVKELREEKRIIESIDIDLQ
CCCCCCCEEEEECCCCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEE
ILEEGGLILLDVSCPEENLKIVESDLNNILKELTRDLVTNKDLERAKKLVVNNIYFGLEL
EECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEE
SSQIASTLGNQALWGRHNSILKSIDDISYWTTKRLNELIFPLFDPENAFTLIAEPEK
HHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCC
>Mature Secondary Structure
MCFKKFRMKVKHWSLSNGATCVVADIEDSTLTCIDFWCKGGSLCEMKGEEGMAHFLEHMI
CCCHHHHHHHHEEECCCCCEEEEEECCCCEEEEEEECCCCCCEEEECCCCCHHHHHHHHH
FKGSKNLKEGEFDLKIESLGGSSNAATGLDDVHYHVLVPREKIEEGLKLILELLLFPKIE
HCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCC
QDAFEMEKEVVLEEIAQNIDQPDEIIYMKLLKGCLTPHRYSKPILGDETTVKNINPKQMK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
LFHKNHYVGKNCTLCIAGDLPNEVQSIINNSKLKELKTISKETAISNTITFNKGYTKKTI
HHHHCCCCCCCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCCCHHCC
PRLEGGRILKAWKLPPAKEQILILGAEIAATMLCEGKSSLIVKELREEKRIIESIDIDLQ
CCCCCCCEEEEECCCCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEE
ILEEGGLILLDVSCPEENLKIVESDLNNILKELTRDLVTNKDLERAKKLVVNNIYFGLEL
EECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEE
SSQIASTLGNQALWGRHNSILKSIDDISYWTTKRLNELIFPLFDPENAFTLIAEPEK
HHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA