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The map label for this gene is selU [H]

Identifier: 124025475

GI number: 124025475

Start: 701303

End: 702355

Strand: Reverse

Name: selU [H]

Synonym: NATL1_07681

Alternate gene names: 124025475

Gene position: 702355-701303 (Counterclockwise)

Preceding gene: 124025478

Following gene: 124025474

Centisome position: 37.67

GC content: 31.81

Gene sequence:

>1053_bases
ATGTCAGAGAAACCTACCAATTCGAGCTATCCTGTTACGGATTTTCGAAATTTAACCAGCCCAATTATAGATGTAAGAAG
TCCCAGCGAATTTCACCAAGGTCATTTGCCGGGTGCTGTCAATATTCCTTTGTTTTCTGATAGCGAAAGAGAGACAATTG
GTAAAAGTTATAAAAAAGAAAGTCGCCTAAAAGCAATACTTCAGGGTTTAAAAGTAACCATTCCTAATGCTAAAAATCTA
TTAGAAATAATCCTACAAATCACCACAAAAAAAGAAGGAAAAAATAAATCATTACGAATATATTGTTGGAGAGGTGGTAT
GAGATCTAGTTCTTTTGCCTGGCTTGCTCGAACAATAGGTATTAGGACATATTTATTAAAAGGTGGATATAAAAACTATA
GAAAATGGGTCTTAAATCAATTTGAGGCTGATTTACCAATAAGACTTTTAGGAGGTAAAACAGGTACGAGAAAAACAGAC
TTATTAAACTATATAAATGAAGAAAATATACATATAATTGATCTAGAGGGAATCGCTAATCATAGAGGGAGTAGTTTTGG
TTCATTAGGTATGAAGGAGCAGCCATCAACACAACAATTTGAAAATATTCTCGCAGAATCTCTTGATAGCTTTCAAAAAA
ATAGTGCTATTGAGATATGGCTTGAAGCTGAAAGTTCTAATCTAGGTAAATGTCGTATACCAAATAGTTTGTATACAAAA
ATGAAAAAAGCTCCAATCCTTGAAATAATTAAAGAAAAGGATGAACGGATAAAAAATTTAGTCCATGTTTATAGCCAAAA
TTCTCAAACTGACTTAAATAATGCTGTAAATAGAATAAGCAAAAGATTAGGTCCACAAAGAACAAAAGAGGCATTAACGG
CAATTAAAAGAAAAGAATGGTCAAAAGCCTGTGAATCCATGCTGGATTATTATGACAAGTGTTATGAATATGAGCTTAAG
AAAACAACTAATATAAATTCAATTAATCTTAGTGGTTTAAGCCTAAAATCATCAGTAAATAAAATCTTAAATGAGAAGCT
CAATCCCTTATAG

Upstream 100 bases:

>100_bases
TAAATGCCCCCAAGAACTCCTCTATGCTCTCTTTGCTTGGATGTGATTTTTCTTCAGTCATGATCAACTGCAGGCCTAAA
ATGACCTAAGCACTAATACT

Downstream 100 bases:

>100_bases
TTTTAATAAAGAAATTTCTATTAATTAAATAAAAAGAAAAGATGACTAAAATCAATGAGAATGTTGCAATTCAATTTGTT
AAAGGGGAAAACGAAAAAGA

Product: tRNA 2-selenouridine synthase

Products: NA

Alternate protein names: Selenophosphate-dependent tRNA 2-selenouridine synthase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSEKPTNSSYPVTDFRNLTSPIIDVRSPSEFHQGHLPGAVNIPLFSDSERETIGKSYKKESRLKAILQGLKVTIPNAKNL
LEIILQITTKKEGKNKSLRIYCWRGGMRSSSFAWLARTIGIRTYLLKGGYKNYRKWVLNQFEADLPIRLLGGKTGTRKTD
LLNYINEENIHIIDLEGIANHRGSSFGSLGMKEQPSTQQFENILAESLDSFQKNSAIEIWLEAESSNLGKCRIPNSLYTK
MKKAPILEIIKEKDERIKNLVHVYSQNSQTDLNNAVNRISKRLGPQRTKEALTAIKRKEWSKACESMLDYYDKCYEYELK
KTTNINSINLSGLSLKSSVNKILNEKLNPL

Sequences:

>Translated_350_residues
MSEKPTNSSYPVTDFRNLTSPIIDVRSPSEFHQGHLPGAVNIPLFSDSERETIGKSYKKESRLKAILQGLKVTIPNAKNL
LEIILQITTKKEGKNKSLRIYCWRGGMRSSSFAWLARTIGIRTYLLKGGYKNYRKWVLNQFEADLPIRLLGGKTGTRKTD
LLNYINEENIHIIDLEGIANHRGSSFGSLGMKEQPSTQQFENILAESLDSFQKNSAIEIWLEAESSNLGKCRIPNSLYTK
MKKAPILEIIKEKDERIKNLVHVYSQNSQTDLNNAVNRISKRLGPQRTKEALTAIKRKEWSKACESMLDYYDKCYEYELK
KTTNINSINLSGLSLKSSVNKILNEKLNPL
>Mature_349_residues
SEKPTNSSYPVTDFRNLTSPIIDVRSPSEFHQGHLPGAVNIPLFSDSERETIGKSYKKESRLKAILQGLKVTIPNAKNLL
EIILQITTKKEGKNKSLRIYCWRGGMRSSSFAWLARTIGIRTYLLKGGYKNYRKWVLNQFEADLPIRLLGGKTGTRKTDL
LNYINEENIHIIDLEGIANHRGSSFGSLGMKEQPSTQQFENILAESLDSFQKNSAIEIWLEAESSNLGKCRIPNSLYTKM
KKAPILEIIKEKDERIKNLVHVYSQNSQTDLNNAVNRISKRLGPQRTKEALTAIKRKEWSKACESMLDYYDKCYEYELKK
TTNINSINLSGLSLKSSVNKILNEKLNPL

Specific function: Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA [H]

COG id: COG2603

COG function: function code R; Predicted ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1786712, Length=344, Percent_Identity=30.8139534883721, Blast_Score=130, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR017582 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 39862; Mature: 39731

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00380 RHODANESE_1 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKPTNSSYPVTDFRNLTSPIIDVRSPSEFHQGHLPGAVNIPLFSDSERETIGKSYKKE
CCCCCCCCCCCCHHHHHHHHHHEECCCCHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHH
SRLKAILQGLKVTIPNAKNLLEIILQITTKKEGKNKSLRIYCWRGGMRSSSFAWLARTIG
HHHHHHHHCCEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
IRTYLLKGGYKNYRKWVLNQFEADLPIRLLGGKTGTRKTDLLNYINEENIHIIDLEGIAN
HHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCC
HRGSSFGSLGMKEQPSTQQFENILAESLDSFQKNSAIEIWLEAESSNLGKCRIPNSLYTK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEECCHHHHHH
MKKAPILEIIKEKDERIKNLVHVYSQNSQTDLNNAVNRISKRLGPQRTKEALTAIKRKEW
HHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
SKACESMLDYYDKCYEYELKKTTNINSINLSGLSLKSSVNKILNEKLNPL
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEKPTNSSYPVTDFRNLTSPIIDVRSPSEFHQGHLPGAVNIPLFSDSERETIGKSYKKE
CCCCCCCCCCCHHHHHHHHHHEECCCCHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHH
SRLKAILQGLKVTIPNAKNLLEIILQITTKKEGKNKSLRIYCWRGGMRSSSFAWLARTIG
HHHHHHHHCCEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
IRTYLLKGGYKNYRKWVLNQFEADLPIRLLGGKTGTRKTDLLNYINEENIHIIDLEGIAN
HHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCC
HRGSSFGSLGMKEQPSTQQFENILAESLDSFQKNSAIEIWLEAESSNLGKCRIPNSLYTK
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEECCHHHHHH
MKKAPILEIIKEKDERIKNLVHVYSQNSQTDLNNAVNRISKRLGPQRTKEALTAIKRKEW
HHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
SKACESMLDYYDKCYEYELKKTTNINSINLSGLSLKSSVNKILNEKLNPL
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA