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The map label for this gene is fur [H]

Identifier: 124025409

GI number: 124025409

Start: 642979

End: 643410

Strand: Direct

Name: fur [H]

Synonym: NATL1_07001

Alternate gene names: 124025409

Gene position: 642979-643410 (Clockwise)

Preceding gene: 124025406

Following gene: 124025412

Centisome position: 34.48

GC content: 38.66

Gene sequence:

>432_bases
TTGATATTGGTTTCTCCCCCTGCCTATCGAAGTCATCCTTCTCCTTTTGAATCTGGCCTTCGTTCAGATGGTAAAAGAAT
GACCCCTCAAAGGAAAAAGGTTCTTTCTCTGTTTGAAGAGATTGGGTCTGGAATCCATCTAAGCGCGGAGGAGGTACATT
CCAAGTTGACAATTTCTGGGGAGAAGGTTTCTCTTGCGACTATTTACAGAACTTTAAGACTCTTGGTCAAGATGACCTTC
CTTAATGAACTTGATTTAAGTGAAGGAGGGAATAGGTTCGAATTGCTTAGTCATGACCATCCAGATCATCATCATTTGAT
TTGTATTCGTTGTGGTAGAACTGAAGAGTTTGAAAATAATAATGTTATTAATGCTGGTAAAGCAGCAGCTAAAAACTTTG
GATTTAAATTATTGGAGTCATCGTTAACGTAA

Upstream 100 bases:

>100_bases
CTAATAAATTTAAACATGATTTTTATCGAAAAGAATCTGAAAAAGCCTTCCCTTTTGTTGCGGGCTGTTCTCATTACGCT
ATGCTATTGAGAAAGCAAAG

Downstream 100 bases:

>100_bases
GAGCGTTATGTCCCAAGTGTTCTAACAAATAAACCTTTTTTTTAAGTTAATTCTCCACCACAACTTGAACCCGCTCCAGC
AGTACATCCAAAACAATGAT

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MILVSPPAYRSHPSPFESGLRSDGKRMTPQRKKVLSLFEEIGSGIHLSAEEVHSKLTISGEKVSLATIYRTLRLLVKMTF
LNELDLSEGGNRFELLSHDHPDHHHLICIRCGRTEEFENNNVINAGKAAAKNFGFKLLESSLT

Sequences:

>Translated_143_residues
MILVSPPAYRSHPSPFESGLRSDGKRMTPQRKKVLSLFEEIGSGIHLSAEEVHSKLTISGEKVSLATIYRTLRLLVKMTF
LNELDLSEGGNRFELLSHDHPDHHHLICIRCGRTEEFENNNVINAGKAAAKNFGFKLLESSLT
>Mature_143_residues
MILVSPPAYRSHPSPFESGLRSDGKRMTPQRKKVLSLFEEIGSGIHLSAEEVHSKLTISGEKVSLATIYRTLRLLVKMTF
LNELDLSEGGNRFELLSHDHPDHHHLICIRCGRTEEFENNNVINAGKAAAKNFGFKLLESSLT

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates genes involved in iron scavenging or photosynthetic electron transport [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=125, Percent_Identity=31.2, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16012; Mature: 16012

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVSPPAYRSHPSPFESGLRSDGKRMTPQRKKVLSLFEEIGSGIHLSAEEVHSKLTISG
CEEECCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECHHHHHHEEECCC
EKVSLATIYRTLRLLVKMTFLNELDLSEGGNRFELLSHDHPDHHHLICIRCGRTEEFENN
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCC
NVINAGKAAAKNFGFKLLESSLT
CCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILVSPPAYRSHPSPFESGLRSDGKRMTPQRKKVLSLFEEIGSGIHLSAEEVHSKLTISG
CEEECCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECHHHHHHEEECCC
EKVSLATIYRTLRLLVKMTFLNELDLSEGGNRFELLSHDHPDHHHLICIRCGRTEEFENN
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCC
NVINAGKAAAKNFGFKLLESSLT
CCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704986 [H]