| Definition | Prochlorococcus marinus str. NATL1A, complete genome. |
|---|---|
| Accession | NC_008819 |
| Length | 1,864,731 |
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The map label for this gene is murF [H]
Identifier: 124025377
GI number: 124025377
Start: 612464
End: 613861
Strand: Direct
Name: murF [H]
Synonym: NATL1_06661
Alternate gene names: 124025377
Gene position: 612464-613861 (Clockwise)
Preceding gene: 124025376
Following gene: 124025381
Centisome position: 32.84
GC content: 36.19
Gene sequence:
>1398_bases ATGGATATTACTTTTAAGGACTTAATTAAACTTTGGGGGACGCTAGATAATCAAAAGGAAATAGATCTTGATTTACCTAT TGGTCGTATATCTACTGATTCGAGGACAATCGAAAAAGGTGATTTCTTTGTCCCTTTGGTAGGTAATACATTTGATGGGC ATGATTACTTAGATATGGCTTTTGATCTTGGTATACAGGCAGCAGTAGTTTCTGAAAAATATAATGGTTTGGTACCAACT GGCCTGCCTCACTGGGTGGTTCCAGATACTCTGTACGCATATCAACAGATCGCATTGCTTCATCGAAGAAATTTAAGTCT TCCTGTAGTTGCTGTTACTGGCTCTGTTGGTAAAACAACTACAAGAGAATTGATTCGAGCAATATTGTCTCCTCTTGGTG AAATTGTCTCTAGCAGAGGGAATGAAAATAATGATGTAGGTGTTCCAAAAACTTTGCTTAGTGGGTCGGAAACAGATGCT GCATTTGTTCTTGAAATGGGTATGCGTGGTTTTGGTCAAATCACACGTCTCTCTCGAGTCGCTGAACCTGATATCGCTGT AATTACAAATGTGGGACAAGCTCATATTGGCATTCTTGGTAGTAGAGAAAATATTGCAAAAGCCAAGTCAGAAATCACCT CATACTTAAGCCCTGATGGTGTTGTGATTATTCCTTTTGGCGATTACATCTTAGAAAAAGCTTTGTTAGAAAAATGGTCA GGACGTATTGTTCGAGTAGAGATAGAGGGCTTTTCACTGAATTGGTTAGATTGTAATAATGAGCATTTTGCTCTTCAAGA TATTGAACCAGATTATATTTCTCAAATTGATATGCAAAATAATTTCATTCTTTTTGAGGGAAGAAAATTCAAATTGCCCC TTGAAGGAAGACATAATGCTATGAATTTTCTTCTGGCATTAACTGTCGCAACAGAATTAGGACTATCAATAAAGAAACTT GATCAATTAAAAATAAATATGCCAATAGGAAGAAATAGATTGGTTGATTGTGGACAATATTTAGTATTAGATGAGACTTA CAATGCATCTCCTGAATCTGTTATTGCATCTCTAGAGTTATTGGTAAGCAAGCCTGGTAGACATTTTGCGGTTTTAGGTA CGATGCTTGAGTTGGGCTCTGAGAGTATTTTACTGCATCAGAAAGTTCTTAAAAAAGCAATTGAATTAGGTCTGACTGGT ATTGTTTTCGTCTCTTGTGGGGAGGAATCTAATATCATAAAAAAGACAATTAAAGAATTACCAAATCATGATGTAGTAAG TACACCAAAAGATGCGGCTATGTCACTGCTACCATGGCTTTCGCCGGGAGACAATATTTTAATTAAAGGTAGTCGTAAGT TGGAATTAGAAAAAGTATTACCTTTTTTACAGAAATAA
Upstream 100 bases:
>100_bases TTCTTATGGCCAAGAAGCAGATCCTTCAAGAAAAGGCAAAAAAATAAAATTATAGGATTTTTGAGTATTTAGATTACTTT GCTTCTATTCAAATATTTGT
Downstream 100 bases:
>100_bases CTTCGCCGTTATAGTTAATCAGCCTTAGTTCTAATAATTGCTTTTGATCTTTCAACTACTAAACTTTTATCTGGAATATC TTTACTTATTGTTGAGCCTG
Product: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase
Products: NA
Alternate protein names: D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetase [H]
Number of amino acids: Translated: 465; Mature: 465
Protein sequence:
>465_residues MDITFKDLIKLWGTLDNQKEIDLDLPIGRISTDSRTIEKGDFFVPLVGNTFDGHDYLDMAFDLGIQAAVVSEKYNGLVPT GLPHWVVPDTLYAYQQIALLHRRNLSLPVVAVTGSVGKTTTRELIRAILSPLGEIVSSRGNENNDVGVPKTLLSGSETDA AFVLEMGMRGFGQITRLSRVAEPDIAVITNVGQAHIGILGSRENIAKAKSEITSYLSPDGVVIIPFGDYILEKALLEKWS GRIVRVEIEGFSLNWLDCNNEHFALQDIEPDYISQIDMQNNFILFEGRKFKLPLEGRHNAMNFLLALTVATELGLSIKKL DQLKINMPIGRNRLVDCGQYLVLDETYNASPESVIASLELLVSKPGRHFAVLGTMLELGSESILLHQKVLKKAIELGLTG IVFVSCGEESNIIKKTIKELPNHDVVSTPKDAAMSLLPWLSPGDNILIKGSRKLELEKVLPFLQK
Sequences:
>Translated_465_residues MDITFKDLIKLWGTLDNQKEIDLDLPIGRISTDSRTIEKGDFFVPLVGNTFDGHDYLDMAFDLGIQAAVVSEKYNGLVPT GLPHWVVPDTLYAYQQIALLHRRNLSLPVVAVTGSVGKTTTRELIRAILSPLGEIVSSRGNENNDVGVPKTLLSGSETDA AFVLEMGMRGFGQITRLSRVAEPDIAVITNVGQAHIGILGSRENIAKAKSEITSYLSPDGVVIIPFGDYILEKALLEKWS GRIVRVEIEGFSLNWLDCNNEHFALQDIEPDYISQIDMQNNFILFEGRKFKLPLEGRHNAMNFLLALTVATELGLSIKKL DQLKINMPIGRNRLVDCGQYLVLDETYNASPESVIASLELLVSKPGRHFAVLGTMLELGSESILLHQKVLKKAIELGLTG IVFVSCGEESNIIKKTIKELPNHDVVSTPKDAAMSLLPWLSPGDNILIKGSRKLELEKVLPFLQK >Mature_465_residues MDITFKDLIKLWGTLDNQKEIDLDLPIGRISTDSRTIEKGDFFVPLVGNTFDGHDYLDMAFDLGIQAAVVSEKYNGLVPT GLPHWVVPDTLYAYQQIALLHRRNLSLPVVAVTGSVGKTTTRELIRAILSPLGEIVSSRGNENNDVGVPKTLLSGSETDA AFVLEMGMRGFGQITRLSRVAEPDIAVITNVGQAHIGILGSRENIAKAKSEITSYLSPDGVVIIPFGDYILEKALLEKWS GRIVRVEIEGFSLNWLDCNNEHFALQDIEPDYISQIDMQNNFILFEGRKFKLPLEGRHNAMNFLLALTVATELGLSIKKL DQLKINMPIGRNRLVDCGQYLVLDETYNASPESVIASLELLVSKPGRHFAVLGTMLELGSESILLHQKVLKKAIELGLTG IVFVSCGEESNIIKKTIKELPNHDVVSTPKDAAMSLLPWLSPGDNILIKGSRKLELEKVLPFLQK
Specific function: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein [H]
COG id: COG0770
COG function: function code M; UDP-N-acetylmuramyl pentapeptide synthase
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786274, Length=448, Percent_Identity=31.4732142857143, Blast_Score=162, Evalue=5e-41,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005863 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.10 [H]
Molecular weight: Translated: 51352; Mature: 51352
Theoretical pI: Translated: 5.35; Mature: 5.35
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDITFKDLIKLWGTLDNQKEIDLDLPIGRISTDSRTIEKGDFFVPLVGNTFDGHDYLDMA CCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEECCCEEEEEECCCCCCCHHHHHH FDLGIQAAVVSEKYNGLVPTGLPHWVVPDTLYAYQQIALLHRRNLSLPVVAVTGSVGKTT HHCCCEEEEEHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHH TRELIRAILSPLGEIVSSRGNENNDVGVPKTLLSGSETDAAFVLEMGMRGFGQITRLSRV HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHH AEPDIAVITNVGQAHIGILGSRENIAKAKSEITSYLSPDGVVIIPFGDYILEKALLEKWS CCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHC GRIVRVEIEGFSLNWLDCNNEHFALQDIEPDYISQIDMQNNFILFEGRKFKLPLEGRHNA CCEEEEEEECEEEEEEECCCCEEEEECCCHHHHHHCCCCCCEEEEECCEEEECCCCCCHH MNFLLALTVATELGLSIKKLDQLKINMPIGRNRLVDCGQYLVLDETYNASPESVIASLEL HHHHHHHHHHHHHCCCHHHHCEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH LVSKPGRHFAVLGTMLELGSESILLHQKVLKKAIELGLTGIVFVSCGEESNIIKKTIKEL HHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHC PNHDVVSTPKDAAMSLLPWLSPGDNILIKGSRKLELEKVLPFLQK CCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCEEHHHHHHHHCC >Mature Secondary Structure MDITFKDLIKLWGTLDNQKEIDLDLPIGRISTDSRTIEKGDFFVPLVGNTFDGHDYLDMA CCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEECCCEEEEEECCCCCCCHHHHHH FDLGIQAAVVSEKYNGLVPTGLPHWVVPDTLYAYQQIALLHRRNLSLPVVAVTGSVGKTT HHCCCEEEEEHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHH TRELIRAILSPLGEIVSSRGNENNDVGVPKTLLSGSETDAAFVLEMGMRGFGQITRLSRV HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHH AEPDIAVITNVGQAHIGILGSRENIAKAKSEITSYLSPDGVVIIPFGDYILEKALLEKWS CCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHC GRIVRVEIEGFSLNWLDCNNEHFALQDIEPDYISQIDMQNNFILFEGRKFKLPLEGRHNA CCEEEEEEECEEEEEEECCCCEEEEECCCHHHHHHCCCCCCEEEEECCEEEECCCCCCHH MNFLLALTVATELGLSIKKLDQLKINMPIGRNRLVDCGQYLVLDETYNASPESVIASLEL HHHHHHHHHHHHHCCCHHHHCEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH LVSKPGRHFAVLGTMLELGSESILLHQKVLKKAIELGLTGIVFVSCGEESNIIKKTIKEL HHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHC PNHDVVSTPKDAAMSLLPWLSPGDNILIKGSRKLELEKVLPFLQK CCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCEEHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7894708; 8905231 [H]