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The map label for this gene is folB [H]

Identifier: 124025358

GI number: 124025358

Start: 591462

End: 591851

Strand: Direct

Name: folB [H]

Synonym: NATL1_06471

Alternate gene names: 124025358

Gene position: 591462-591851 (Clockwise)

Preceding gene: 124025357

Following gene: 124025359

Centisome position: 31.72

GC content: 31.03

Gene sequence:

>390_bases
ATGAGTCAACTTCATAATTTAAGCGCAATTCATATCAAAGATATTAATCTATGGGCTCATGTAGGTGTTTTAGAAAGTGA
GCGAATACATGGTCAAAGATTTCTTCTTGACCTCAGTTTTTGGTTGGAATTGGATGAGTCATCCAAGCTTGATAAATTAG
ATAAATCGATAGATTATAGCGAGGCAATTAAAGCTGTTAAAAAACTTTCATTTGAAATCAAATGCTTAACGATTGAATAT
TTTAGTGATCAAATTTTGAATCTTCTTGAGTCTCTATATGGTCCAGTCCCAATTCATATTCTGCTTACAAAATGCTCTCC
ACCAATAGATGGATTTACTGGAAGTGTTCTAATCGAAAAAAAAAGAAATTTCTTATTTCCTATTAATTAA

Upstream 100 bases:

>100_bases
AAGGCTTAGTTACCTATCGCTATTATCTCAGAGGTGATGGTGATCTCGTTAAGGACTTCGCTTCTGGAGATAGAAGTTTT
TCTCATATTGATCTACCATT

Downstream 100 bases:

>100_bases
TTGTATATAAACAAAAGACCAATTTTTCTTGTTCATGGTTTGTGGAACAATCCTAAATTATTTGAAAAATTAATTAAAAA
AATAAACGAAGATGATTATG

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MSQLHNLSAIHIKDINLWAHVGVLESERIHGQRFLLDLSFWLELDESSKLDKLDKSIDYSEAIKAVKKLSFEIKCLTIEY
FSDQILNLLESLYGPVPIHILLTKCSPPIDGFTGSVLIEKKRNFLFPIN

Sequences:

>Translated_129_residues
MSQLHNLSAIHIKDINLWAHVGVLESERIHGQRFLLDLSFWLELDESSKLDKLDKSIDYSEAIKAVKKLSFEIKCLTIEY
FSDQILNLLESLYGPVPIHILLTKCSPPIDGFTGSVLIEKKRNFLFPIN
>Mature_128_residues
SQLHNLSAIHIKDINLWAHVGVLESERIHGQRFLLDLSFWLELDESSKLDKLDKSIDYSEAIKAVKKLSFEIKCLTIEYF
SDQILNLLESLYGPVPIHILLTKCSPPIDGFTGSVLIEKKRNFLFPIN

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14796; Mature: 14665

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLHNLSAIHIKDINLWAHVGVLESERIHGQRFLLDLSFWLELDESSKLDKLDKSIDYS
CCCCCCCEEEEEEECEEEEEECCCCCCCCCCEEEEEEEEEEEEECCCCCHHHHHCCCCHH
EAIKAVKKLSFEIKCLTIEYFSDQILNLLESLYGPVPIHILLTKCSPPIDGFTGSVLIEK
HHHHHHHHCCEEEEEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEC
KRNFLFPIN
CCCEEECCC
>Mature Secondary Structure 
SQLHNLSAIHIKDINLWAHVGVLESERIHGQRFLLDLSFWLELDESSKLDKLDKSIDYS
CCCCCCEEEEEEECEEEEEECCCCCCCCCCEEEEEEEEEEEEECCCCCHHHHHCCCCHH
EAIKAVKKLSFEIKCLTIEYFSDQILNLLESLYGPVPIHILLTKCSPPIDGFTGSVLIEK
HHHHHHHHCCEEEEEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEC
KRNFLFPIN
CCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]