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The map label for this gene is ecm27 [H]

Identifier: 124025334

GI number: 124025334

Start: 566950

End: 568044

Strand: Reverse

Name: ecm27 [H]

Synonym: NATL1_06231

Alternate gene names: 124025334

Gene position: 568044-566950 (Counterclockwise)

Preceding gene: 124025340

Following gene: 124025332

Centisome position: 30.46

GC content: 37.26

Gene sequence:

>1095_bases
ATGCCATCAATATTATTGTCATTTTTAGAGCTTATTGCTGGGATACTTTTACTTTTTAGCGGCGGGGAGTTCTTTATTCA
AGGATCTGTAGCTTTAGCCTTAATCCTTGGGATTCCTCAACTAGTCATTGGTTTAACAATAGTATCTCTCGGGACAAGTG
CACCTGAACTATTTGTGAGTGTCAACTCCTCCCTCAATGGATCAGATAGTCTAGCGTTGAGCAACATTGTTGGCAGCAAT
ATTTTCAATGTGATGGTAGTTCTCGGAGGAAGTGCACTTTTACGACCATTAAGAGTTGAAAGTCGTCTTGTAAGAAGAGA
CATTCCTCTTCTTTTAGCAGTCTCAACTGCCGTTTGGGGGATGGCCGCTTCAGAGCTGATAACTTGGCAATTTGGAGTAG
CTTTAATAGTTGCGCTAATAATAAATACCACTTGGGAAATTCGCACAGCAAGAGAGGAACCTCAAAAAACCCAAGAAGCA
GAGCCAGAAATCAATATAGAAAAAGACTCAACAAGTTTATTAAATGCAGGCGTGAAATTATTAGGTGGTATTTTCTTGCT
AACTCTTGGATCACGACTTTTAATAGAAGGCGCATCTACAATTGCAGGGTTGTTAGGGATAAGCGAAGCTATAATTGGGT
TAACGATAGTTTCACTGGGCACTTCTTTACCTGAGTTAATTACGTCATTAGTGGCCGCCATTCGTGGTCAAACTGATCTA
GCGATAGGCAACGTAATTGGAAGTTGTTTATTAAATCAATTACTAGTTTTAGGTAGCTGTTCTGTATTATCTGGAGGCAG
TGGTTTAGTGGTTGAGAGTTTACTAATAACTAAGGATATTCCTATCATGGTAATTACTACACTTGCGTGCATGCCAATTT
TTTGGACAAAAGGAATAATAAGTAGAGGAGAAGGTGGCGTTTTATTAGGATTGTATATGCTTTACATTGCAGACAAAATA
ATACCTCTAACTCTACCAACTTTACATACAGCATTCAAAGAATTAGTTTTTATAGCTATATCATTATCAATAACAATAAT
TATATACAAAACAATTGCTTACTGGTTAAGACTAAGAAAAAGGTCTAATAACTAA

Upstream 100 bases:

>100_bases
GTCTTCAAGTATCCATAAAGGGCTAAGATATTAAGATAATACCAAATGGAAATAATATAAATTAATTCACTAATTTAGTT
TCTCAATAAATCACTCAATT

Downstream 100 bases:

>100_bases
TGCCTTCTCTAAATCATCTCATTGTCACGAATTCCTCGGCTATTGTAGGATGCAATGCCATTGTATTATCAAAGTCAGTT
TTTTTAGCACCTAGCATTAG

Product: CaCA family sodium/calcium exchanger

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MPSILLSFLELIAGILLLFSGGEFFIQGSVALALILGIPQLVIGLTIVSLGTSAPELFVSVNSSLNGSDSLALSNIVGSN
IFNVMVVLGGSALLRPLRVESRLVRRDIPLLLAVSTAVWGMAASELITWQFGVALIVALIINTTWEIRTAREEPQKTQEA
EPEINIEKDSTSLLNAGVKLLGGIFLLTLGSRLLIEGASTIAGLLGISEAIIGLTIVSLGTSLPELITSLVAAIRGQTDL
AIGNVIGSCLLNQLLVLGSCSVLSGGSGLVVESLLITKDIPIMVITTLACMPIFWTKGIISRGEGGVLLGLYMLYIADKI
IPLTLPTLHTAFKELVFIAISLSITIIIYKTIAYWLRLRKRSNN

Sequences:

>Translated_364_residues
MPSILLSFLELIAGILLLFSGGEFFIQGSVALALILGIPQLVIGLTIVSLGTSAPELFVSVNSSLNGSDSLALSNIVGSN
IFNVMVVLGGSALLRPLRVESRLVRRDIPLLLAVSTAVWGMAASELITWQFGVALIVALIINTTWEIRTAREEPQKTQEA
EPEINIEKDSTSLLNAGVKLLGGIFLLTLGSRLLIEGASTIAGLLGISEAIIGLTIVSLGTSLPELITSLVAAIRGQTDL
AIGNVIGSCLLNQLLVLGSCSVLSGGSGLVVESLLITKDIPIMVITTLACMPIFWTKGIISRGEGGVLLGLYMLYIADKI
IPLTLPTLHTAFKELVFIAISLSITIIIYKTIAYWLRLRKRSNN
>Mature_363_residues
PSILLSFLELIAGILLLFSGGEFFIQGSVALALILGIPQLVIGLTIVSLGTSAPELFVSVNSSLNGSDSLALSNIVGSNI
FNVMVVLGGSALLRPLRVESRLVRRDIPLLLAVSTAVWGMAASELITWQFGVALIVALIINTTWEIRTAREEPQKTQEAE
PEINIEKDSTSLLNAGVKLLGGIFLLTLGSRLLIEGASTIAGLLGISEAIIGLTIVSLGTSLPELITSLVAAIRGQTDLA
IGNVIGSCLLNQLLVLGSCSVLSGGSGLVVESLLITKDIPIMVITTLACMPIFWTKGIISRGEGGVLLGLYMLYIADKII
PLTLPTLHTAFKELVFIAISLSITIIIYKTIAYWLRLRKRSNN

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=302, Percent_Identity=31.1258278145695, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 38599; Mature: 38467

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSILLSFLELIAGILLLFSGGEFFIQGSVALALILGIPQLVIGLTIVSLGTSAPELFVS
CHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VNSSLNGSDSLALSNIVGSNIFNVMVVLGGSALLRPLRVESRLVRRDIPLLLAVSTAVWG
ECCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
MAASELITWQFGVALIVALIINTTWEIRTAREEPQKTQEAEPEINIEKDSTSLLNAGVKL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCCEEEECCHHHHHHHHHHH
LGGIFLLTLGSRLLIEGASTIAGLLGISEAIIGLTIVSLGTSLPELITSLVAAIRGQTDL
HHHHHHHHHCCHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHH
AIGNVIGSCLLNQLLVLGSCSVLSGGSGLVVESLLITKDIPIMVITTLACMPIFWTKGII
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SRGEGGVLLGLYMLYIADKIIPLTLPTLHTAFKELVFIAISLSITIIIYKTIAYWLRLRK
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSNN
CCCC
>Mature Secondary Structure 
PSILLSFLELIAGILLLFSGGEFFIQGSVALALILGIPQLVIGLTIVSLGTSAPELFVS
HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VNSSLNGSDSLALSNIVGSNIFNVMVVLGGSALLRPLRVESRLVRRDIPLLLAVSTAVWG
ECCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
MAASELITWQFGVALIVALIINTTWEIRTAREEPQKTQEAEPEINIEKDSTSLLNAGVKL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCCEEEECCHHHHHHHHHHH
LGGIFLLTLGSRLLIEGASTIAGLLGISEAIIGLTIVSLGTSLPELITSLVAAIRGQTDL
HHHHHHHHHCCHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHH
AIGNVIGSCLLNQLLVLGSCSVLSGGSGLVVESLLITKDIPIMVITTLACMPIFWTKGII
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SRGEGGVLLGLYMLYIADKIIPLTLPTLHTAFKELVFIAISLSITIIIYKTIAYWLRLRK
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSNN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]