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The map label for this gene is frr

Identifier: 124025289

GI number: 124025289

Start: 524229

End: 524777

Strand: Reverse

Name: frr

Synonym: NATL1_05781

Alternate gene names: 124025289

Gene position: 524777-524229 (Counterclockwise)

Preceding gene: 124025290

Following gene: 124025288

Centisome position: 28.14

GC content: 37.16

Gene sequence:

>549_bases
ATGTCAAACCAAGAGCTAAAAAACACAATGAGCAAATCTGTAGAGGCAGCTCAGAGAAATTTCAATACCATCAGGACGGG
AAGGGCAAATACATCTTTGTTAGATAGAATTTCAGTCGAATACTACGGGGCAGAGACTCCACTAAAATCTCTCGCAACTA
TCACTACTCCTGACTCTCAAACGATAGCAATTCAACCCTTCGACTTAGGCTCTTTAGCTTCCATCGAAAAAGCAATTGCA
ACCAGTGATCTGGGTTTTACGCCAAATAATGATGGCAAGATAATTCGTATAAATGTTCCACCATTAACTGAAGAGCGTAG
AAAAGAATTTTGCAAACTCGCCTCAAAGTATGCAGAGGAAGGAAAAGTTGCCTTAAGAAATATACGCCGTGAGGCAATAG
ATAGAGTCAAAAAATCTGAAAAGGATGGTGATCTTTCCGAAGATCAAAGCAGAGATGAACAAGAAAAAATTCAGAAAGAG
ACGGATAATTTTATTAAAGATATTGAAAAAAAACTTTCAGAAAAAGAAGCTGAGATTTTAAAAGTTTGA

Upstream 100 bases:

>100_bases
AAGCTATTTCTGGCGAACCAATCGGATCTAGAATTTCTAATTCAAGTTGAAACTAACTTTTTAAGCTTTTTAAAAATCAA
TTCCCAATAACTTTATCTGA

Downstream 100 bases:

>100_bases
CCCTCATAGATGTTGCCATTATTGGAGGGGGAGCATCAGGTACTACTACAGCATTTCATCTAGCAAGTAAAAGTAAAAAG
GTATGTATTCTTGAAAAAAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MSNQELKNTMSKSVEAAQRNFNTIRTGRANTSLLDRISVEYYGAETPLKSLATITTPDSQTIAIQPFDLGSLASIEKAIA
TSDLGFTPNNDGKIIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRREAIDRVKKSEKDGDLSEDQSRDEQEKIQKE
TDNFIKDIEKKLSEKEAEILKV

Sequences:

>Translated_182_residues
MSNQELKNTMSKSVEAAQRNFNTIRTGRANTSLLDRISVEYYGAETPLKSLATITTPDSQTIAIQPFDLGSLASIEKAIA
TSDLGFTPNNDGKIIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRREAIDRVKKSEKDGDLSEDQSRDEQEKIQKE
TDNFIKDIEKKLSEKEAEILKV
>Mature_181_residues
SNQELKNTMSKSVEAAQRNFNTIRTGRANTSLLDRISVEYYGAETPLKSLATITTPDSQTIAIQPFDLGSLASIEKAIAT
SDLGFTPNNDGKIIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRREAIDRVKKSEKDGDLSEDQSRDEQEKIQKET
DNFIKDIEKKLSEKEAEILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=29.608938547486, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786368, Length=172, Percent_Identity=51.1627906976744, Blast_Score=171, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=26.7045454545455, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PROM1 (A2C0Y0)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014405.1
- ProteinModelPortal:   A2C0Y0
- SMR:   A2C0Y0
- STRING:   A2C0Y0
- GeneID:   4780026
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_05781
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   PMAR167555:NATL1_05781-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20507; Mature: 20376

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQELKNTMSKSVEAAQRNFNTIRTGRANTSLLDRISVEYYGAETPLKSLATITTPDSQ
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHEEECCCCC
TIAIQPFDLGSLASIEKAIATSDLGFTPNNDGKIIRINVPPLTEERRKEFCKLASKYAEE
EEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
GKVALRNIRREAIDRVKKSEKDGDLSEDQSRDEQEKIQKETDNFIKDIEKKLSEKEAEIL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KV
CC
>Mature Secondary Structure 
SNQELKNTMSKSVEAAQRNFNTIRTGRANTSLLDRISVEYYGAETPLKSLATITTPDSQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHEEECCCCC
TIAIQPFDLGSLASIEKAIATSDLGFTPNNDGKIIRINVPPLTEERRKEFCKLASKYAEE
EEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
GKVALRNIRREAIDRVKKSEKDGDLSEDQSRDEQEKIQKETDNFIKDIEKKLSEKEAEIL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA