Click here to switch to the map view.

The map label for this gene is spoVD [H]

Identifier: 124025286

GI number: 124025286

Start: 520211

End: 522007

Strand: Direct

Name: spoVD [H]

Synonym: NATL1_05751

Alternate gene names: 124025286

Gene position: 520211-522007 (Clockwise)

Preceding gene: 124025285

Following gene: 124025287

Centisome position: 27.9

GC content: 39.57

Gene sequence:

>1797_bases
ATGAGAAGTTCTGATCATAGAAAGAAAAGAAAGACTTTTAAAGTAAACACTCTTCAGCCCCTATCTCAGTCCAGATTTAG
AATTATCTTTTTTTTATTATGCCTTGGACTTGGGGGCCTTTTTTTAAGGGTAGGTTGGCTTCAGCTATTTCAGTCTGATC
AATTGAGAGCTTTAGCACGCGAAGTTCAAACAGAACAAAAGACCCCTCTGGGGACACGTCGATCTATTTTAGATAGAAAT
GGAAAGCTTGTCGCAATCGATGAGAGACGTTTTAAAATTTGGGCTCATCCTAGGTATTTTAATTTTCCCGGTGATTCATC
TAGGACAGTGCGTAAACCAGTCGAAGTAGCAAAGCTTCTTTCTTCCCCACTATCCATAAGCGTTGATGATATTTTAAAAA
AATTAGGAAATTATTCTTCAGGGGTAAAACTTGCAGAGGGGGTGACGCCCGAACAAGCTAATGCTATTAAGAAACTTGGA
ATAAGTGGTATTGATTTGGAGGTGTATCCTCAAAGGCTTTATCCTCACGGGTCACTTTTTGCAAATGTAGTTGGTTTTTT
GGATTTAGATAGAAGACCTCAGGCTGGATTGGAATTAAGTTTAGATGGTGATCTAAAGCGTCTAGAAAAAGCAAGTTTAA
TCAGAAGAGGAGCTGATGGAACACCTTTGCCTACAGGTGTTCAACGTGGTGTCTTTGACGAGGATCAACTAAGTCTCCAA
TTAACCCTAGATGTAAGGCTTCAAGAAGTAGCCATTAAAGAAATAAGCAAGCAAGTAAAGAAGTGGAATGCAAAAAAAGG
TGTAGTCATCGTAATGGATATAGATACAGGTGAACTTCTGGCATTGGCTTCTACTCCAACTTATGATCCTAATAAATATT
GGGACTATTCTCCATCTCTTTTTAAAGAGTGGTCAGTGCAAGAATTATTTGAACCTGGTTCTACCTTTAAGCCAATTAAC
TTGGCATTAGCATTGGAGGAGGGGGTTATAAGCCCCAATGGAGAAGTGAATGATGATGGTCTAGTTACAGTAGGAGGATG
GCCTCTCTCTAATTGGGATCGGAGGCCTAACGGGATATTGACTTTTCCTGAAGTGTTACAAGTCTCCAGCAATGTAGGTA
TGGTTAAAATTATGAATAAATTGAATGCGAGTATTTACTGGCAATGGTTAAGGCGCCTAGGCATTGATGAAATACCAGAT
ACTGATCTTCCAGGAGCAGTTTCTGGGCAAATAAAATCAAAGCAGACTTTTGTCAATCAACCGATAGAACCAGCGGTAGC
CTCCTTTGGTCAAGGCTTTTCTGTTACTCCGCTTAAACTAGCTCAATTGCACGCTTTAATTGCAAATGGAGGCAGACTTG
TGACGCCTCATATCACTAAAGGCCTGAAAGGTGATTATGAGTCGTATTTCAATTCTCCTTCAGAACCAAAGCAGGTGTTA
TCTCCTGAGGTTACAAAGACTGTTCTTGGATGGATGGAAACAGTTGTGTCATTTTACGATGAAAGTGGTATTGAGGTAGA
TGTTCCTGGCTATCGAATTGGAGGAAAAACAGGGACGGCACAAAAATCGCAGGATGGTTTTAACTATAATTCTAAAATTT
GCAGTTTTGTTGCAAGTCTTCCTATCGATGATCCTCGCTATGTTGTTTTAGCAGTTATTGATGAACCTCAAAAGCCAAAT
GCATATGGATCAACGGTGGCTCTCCCTGTGGCAAAAAAAATTATTGAGACTTTGCTTGTGATAGAAAAAATCCCTCCAAG
TATTTCTAAAAAAGAACATTTGGCTAGCAAAAGCTAA

Upstream 100 bases:

>100_bases
AACCAGAAGATACTAAAAAATTATTCGATGTGACATTGAAAAGTAGATTTCTAGAGAAAATATCTTCTTTTCCCGTTAAA
TCAGGTTACTAATAATTCCC

Downstream 100 bases:

>100_bases
GAGATGGCTAAATTTTCCCAAAAGTACTACTTAAAAGGTGAAATCTATAAAAAATATGGCTAGTCTATTTCATATGAAAG
ACGTTTTTTATTATGGAATC

Product: peptidoglycan synthetase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MRSSDHRKKRKTFKVNTLQPLSQSRFRIIFFLLCLGLGGLFLRVGWLQLFQSDQLRALAREVQTEQKTPLGTRRSILDRN
GKLVAIDERRFKIWAHPRYFNFPGDSSRTVRKPVEVAKLLSSPLSISVDDILKKLGNYSSGVKLAEGVTPEQANAIKKLG
ISGIDLEVYPQRLYPHGSLFANVVGFLDLDRRPQAGLELSLDGDLKRLEKASLIRRGADGTPLPTGVQRGVFDEDQLSLQ
LTLDVRLQEVAIKEISKQVKKWNAKKGVVIVMDIDTGELLALASTPTYDPNKYWDYSPSLFKEWSVQELFEPGSTFKPIN
LALALEEGVISPNGEVNDDGLVTVGGWPLSNWDRRPNGILTFPEVLQVSSNVGMVKIMNKLNASIYWQWLRRLGIDEIPD
TDLPGAVSGQIKSKQTFVNQPIEPAVASFGQGFSVTPLKLAQLHALIANGGRLVTPHITKGLKGDYESYFNSPSEPKQVL
SPEVTKTVLGWMETVVSFYDESGIEVDVPGYRIGGKTGTAQKSQDGFNYNSKICSFVASLPIDDPRYVVLAVIDEPQKPN
AYGSTVALPVAKKIIETLLVIEKIPPSISKKEHLASKS

Sequences:

>Translated_598_residues
MRSSDHRKKRKTFKVNTLQPLSQSRFRIIFFLLCLGLGGLFLRVGWLQLFQSDQLRALAREVQTEQKTPLGTRRSILDRN
GKLVAIDERRFKIWAHPRYFNFPGDSSRTVRKPVEVAKLLSSPLSISVDDILKKLGNYSSGVKLAEGVTPEQANAIKKLG
ISGIDLEVYPQRLYPHGSLFANVVGFLDLDRRPQAGLELSLDGDLKRLEKASLIRRGADGTPLPTGVQRGVFDEDQLSLQ
LTLDVRLQEVAIKEISKQVKKWNAKKGVVIVMDIDTGELLALASTPTYDPNKYWDYSPSLFKEWSVQELFEPGSTFKPIN
LALALEEGVISPNGEVNDDGLVTVGGWPLSNWDRRPNGILTFPEVLQVSSNVGMVKIMNKLNASIYWQWLRRLGIDEIPD
TDLPGAVSGQIKSKQTFVNQPIEPAVASFGQGFSVTPLKLAQLHALIANGGRLVTPHITKGLKGDYESYFNSPSEPKQVL
SPEVTKTVLGWMETVVSFYDESGIEVDVPGYRIGGKTGTAQKSQDGFNYNSKICSFVASLPIDDPRYVVLAVIDEPQKPN
AYGSTVALPVAKKIIETLLVIEKIPPSISKKEHLASKS
>Mature_598_residues
MRSSDHRKKRKTFKVNTLQPLSQSRFRIIFFLLCLGLGGLFLRVGWLQLFQSDQLRALAREVQTEQKTPLGTRRSILDRN
GKLVAIDERRFKIWAHPRYFNFPGDSSRTVRKPVEVAKLLSSPLSISVDDILKKLGNYSSGVKLAEGVTPEQANAIKKLG
ISGIDLEVYPQRLYPHGSLFANVVGFLDLDRRPQAGLELSLDGDLKRLEKASLIRRGADGTPLPTGVQRGVFDEDQLSLQ
LTLDVRLQEVAIKEISKQVKKWNAKKGVVIVMDIDTGELLALASTPTYDPNKYWDYSPSLFKEWSVQELFEPGSTFKPIN
LALALEEGVISPNGEVNDDGLVTVGGWPLSNWDRRPNGILTFPEVLQVSSNVGMVKIMNKLNASIYWQWLRRLGIDEIPD
TDLPGAVSGQIKSKQTFVNQPIEPAVASFGQGFSVTPLKLAQLHALIANGGRLVTPHITKGLKGDYESYFNSPSEPKQVL
SPEVTKTVLGWMETVVSFYDESGIEVDVPGYRIGGKTGTAQKSQDGFNYNSKICSFVASLPIDDPRYVVLAVIDEPQKPN
AYGSTVALPVAKKIIETLLVIEKIPPSISKKEHLASKS

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=570, Percent_Identity=30.7017543859649, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1786854, Length=502, Percent_Identity=23.3067729083665, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 66263; Mature: 66263

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSDHRKKRKTFKVNTLQPLSQSRFRIIFFLLCLGLGGLFLRVGWLQLFQSDQLRALAR
CCCCHHHHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVQTEQKTPLGTRRSILDRNGKLVAIDERRFKIWAHPRYFNFPGDSSRTVRKPVEVAKLL
HHHHHHCCCCCHHHHHHCCCCCEEEEECCEEEEEECCEEECCCCCCCCHHHHHHHHHHHH
SSPLSISVDDILKKLGNYSSGVKLAEGVTPEQANAIKKLGISGIDLEVYPQRLYPHGSLF
CCCCCCCHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHCCCCCCEEEECHHHHCCCHHHH
ANVVGFLDLDRRPQAGLELSLDGDLKRLEKASLIRRGADGTPLPTGVQRGVFDEDQLSLQ
HHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCEEEE
LTLDVRLQEVAIKEISKQVKKWNAKKGVVIVMDIDTGELLALASTPTYDPNKYWDYSPSL
EEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHH
FKEWSVQELFEPGSTFKPINLALALEEGVISPNGEVNDDGLVTVGGWPLSNWDRRPNGIL
HHHCCHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCE
TFPEVLQVSSNVGMVKIMNKLNASIYWQWLRRLGIDEIPDTDLPGAVSGQIKSKQTFVNQ
ECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCC
PIEPAVASFGQGFSVTPLKLAQLHALIANGGRLVTPHITKGLKGDYESYFNSPSEPKQVL
CCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECHHHHCCCCCCHHHHCCCCCCCHHHH
SPEVTKTVLGWMETVVSFYDESGIEVDVPGYRIGGKTGTAQKSQDGFNYNSKICSFVASL
CHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHC
PIDDPRYVVLAVIDEPQKPNAYGSTVALPVAKKIIETLLVIEKIPPSISKKEHLASKS
CCCCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCC
>Mature Secondary Structure
MRSSDHRKKRKTFKVNTLQPLSQSRFRIIFFLLCLGLGGLFLRVGWLQLFQSDQLRALAR
CCCCHHHHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVQTEQKTPLGTRRSILDRNGKLVAIDERRFKIWAHPRYFNFPGDSSRTVRKPVEVAKLL
HHHHHHCCCCCHHHHHHCCCCCEEEEECCEEEEEECCEEECCCCCCCCHHHHHHHHHHHH
SSPLSISVDDILKKLGNYSSGVKLAEGVTPEQANAIKKLGISGIDLEVYPQRLYPHGSLF
CCCCCCCHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHCCCCCCEEEECHHHHCCCHHHH
ANVVGFLDLDRRPQAGLELSLDGDLKRLEKASLIRRGADGTPLPTGVQRGVFDEDQLSLQ
HHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCEEEE
LTLDVRLQEVAIKEISKQVKKWNAKKGVVIVMDIDTGELLALASTPTYDPNKYWDYSPSL
EEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHH
FKEWSVQELFEPGSTFKPINLALALEEGVISPNGEVNDDGLVTVGGWPLSNWDRRPNGIL
HHHCCHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCE
TFPEVLQVSSNVGMVKIMNKLNASIYWQWLRRLGIDEIPDTDLPGAVSGQIKSKQTFVNQ
ECHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCC
PIEPAVASFGQGFSVTPLKLAQLHALIANGGRLVTPHITKGLKGDYESYFNSPSEPKQVL
CCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECHHHHCCCCCCHHHHCCCCCCCHHHH
SPEVTKTVLGWMETVVSFYDESGIEVDVPGYRIGGKTGTAQKSQDGFNYNSKICSFVASL
CHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHC
PIDDPRYVVLAVIDEPQKPNAYGSTVALPVAKKIIETLLVIEKIPPSISKKEHLASKS
CCCCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]