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The map label for this gene is wecB [C]

Identifier: 124022384

GI number: 124022384

Start: 633295

End: 634407

Strand: Direct

Name: wecB [C]

Synonym: P9303_06751

Alternate gene names: 124022384

Gene position: 633295-634407 (Clockwise)

Preceding gene: 124022381

Following gene: 124022385

Centisome position: 23.61

GC content: 55.8

Gene sequence:

>1113_bases
ATGGCTGGTTTGCCCCGCGTCACGATCGTGCTGGGCACCCGTCCAGAGGCGATCAAGTTGGCACCGGTGATCCAGGCGTT
TCAGGCCTGTGACGCTTTGACGACTCGAGTTGTGCTTACTGGCCAGCACCGCGAGATGGTTGCTCAGGTCATGGATCTAT
TTGGTCTTTCAGCCAATCATGATCTCGATCTGATGGCCCCTCTGCAGACCCTCACTCACGTCACCTGTGCAGCATTGCAA
GGCCTCAAGGATGAATTCAAGGCCTACCCTCCCCAGCTGGTGCTTGTCCAGGGAGATACCACCACAGCATTTGCAGCTGC
CCTTGCTGCTTTTTATGAGCAGATTCCGGTTGGTCATGTTGAGGCTGGTTTGCGCACAGACAACTTGTTGGATCCGTTTC
CTGAAGAGGCAAACCGGCGCCTGATTTCTCAGATCTCCCAGCTTCACTTCGCTCCAACGCCTCGCTCTCAGGCCAATTTG
ACCAGTTCAGGGGTTGTTGGTCAGATCTTTGTTACGGGCAACACAGTGATTGATGCTCTTTTGTTGATGGCTGAGCAGGC
GCCGCCTATCGAATTTGATGGTCTCGACTGGGCGCATCAGCGCGTCATTTTGGCCACCGTGCATCGACGGGAGAATTGGG
GAGATCGGCTTCAAGACATTGCCGAGGGCATGAGAAGGGTTCTTGACCTTCATCCCGACACGGCTTTACTTCTGCCTTTG
CATCGCAATCCAACCGTGCGAGAACCAATGCAGGCACTTTTGGGGAACCATCCGAGGGTGGTACTCACCGAGCCTCTCGA
TTACGACCGTTTGGTTGCTGCGATGAGGGCCTGCACGCTTCTGCTCACAGATTCTGGTGGGCTCCAAGAAGAAGCTCCTG
CGCTGGGTAAGCCAGTTTTGGTTTTGAGACGGACCACCGAACGACCAGAGGCCGTTGAAGCGGGTACGGCCAAGCTGGTT
GGTACCGATCCGGAGATGATCGTGACTGAGACAGCTTCCTTGCTTGATGATTCAAGCGCCTACGAGGCGATGGCACGTGC
TGTCAATCCCTTCGGCGACGGCAAGGCCAGCGGTCGCATTCTTGAGGCAAGTTGTGCATTCCTGGGCGTCTGA

Upstream 100 bases:

>100_bases
CGCTTTCTTCAGCTTCGTCGCGGCGAAGCTCTTGGCAAGTCCGTGCGCACTTTTGGTGATCAGCAAGCACTCTTAGGATC
CCTTCAAGATTGCTTCTCTT

Downstream 100 bases:

>100_bases
GGCTGCCTTTAGTTCTTGCGGTCACTACCGCTGGTGGTTGAAGCGCAGCCTTGGGCAATGCGAGCGCACGTTGCTTTTCA
TTGGCTTGAATCCCTCCACG

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MAGLPRVTIVLGTRPEAIKLAPVIQAFQACDALTTRVVLTGQHREMVAQVMDLFGLSANHDLDLMAPLQTLTHVTCAALQ
GLKDEFKAYPPQLVLVQGDTTTAFAAALAAFYEQIPVGHVEAGLRTDNLLDPFPEEANRRLISQISQLHFAPTPRSQANL
TSSGVVGQIFVTGNTVIDALLLMAEQAPPIEFDGLDWAHQRVILATVHRRENWGDRLQDIAEGMRRVLDLHPDTALLLPL
HRNPTVREPMQALLGNHPRVVLTEPLDYDRLVAAMRACTLLLTDSGGLQEEAPALGKPVLVLRRTTERPEAVEAGTAKLV
GTDPEMIVTETASLLDDSSAYEAMARAVNPFGDGKASGRILEASCAFLGV

Sequences:

>Translated_370_residues
MAGLPRVTIVLGTRPEAIKLAPVIQAFQACDALTTRVVLTGQHREMVAQVMDLFGLSANHDLDLMAPLQTLTHVTCAALQ
GLKDEFKAYPPQLVLVQGDTTTAFAAALAAFYEQIPVGHVEAGLRTDNLLDPFPEEANRRLISQISQLHFAPTPRSQANL
TSSGVVGQIFVTGNTVIDALLLMAEQAPPIEFDGLDWAHQRVILATVHRRENWGDRLQDIAEGMRRVLDLHPDTALLLPL
HRNPTVREPMQALLGNHPRVVLTEPLDYDRLVAAMRACTLLLTDSGGLQEEAPALGKPVLVLRRTTERPEAVEAGTAKLV
GTDPEMIVTETASLLDDSSAYEAMARAVNPFGDGKASGRILEASCAFLGV
>Mature_369_residues
AGLPRVTIVLGTRPEAIKLAPVIQAFQACDALTTRVVLTGQHREMVAQVMDLFGLSANHDLDLMAPLQTLTHVTCAALQG
LKDEFKAYPPQLVLVQGDTTTAFAAALAAFYEQIPVGHVEAGLRTDNLLDPFPEEANRRLISQISQLHFAPTPRSQANLT
SSGVVGQIFVTGNTVIDALLLMAEQAPPIEFDGLDWAHQRVILATVHRRENWGDRLQDIAEGMRRVLDLHPDTALLLPLH
RNPTVREPMQALLGNHPRVVLTEPLDYDRLVAAMRACTLLLTDSGGLQEEAPALGKPVLVLRRTTERPEAVEAGTAKLVG
TDPEMIVTETASLLDDSSAYEAMARAVNPFGDGKASGRILEASCAFLGV

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=373, Percent_Identity=48.7935656836461, Blast_Score=334, Evalue=4e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40044; Mature: 39912

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLPRVTIVLGTRPEAIKLAPVIQAFQACDALTTRVVLTGQHREMVAQVMDLFGLSANH
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHCCCCCC
DLDLMAPLQTLTHVTCAALQGLKDEFKAYPPQLVLVQGDTTTAFAAALAAFYEQIPVGHV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHH
EAGLRTDNLLDPFPEEANRRLISQISQLHFAPTPRSQANLTSSGVVGQIFVTGNTVIDAL
HCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHH
LLMAEQAPPIEFDGLDWAHQRVILATVHRRENWGDRLQDIAEGMRRVLDLHPDTALLLPL
HHHHCCCCCCCCCCCCHHHHEEHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
HRNPTVREPMQALLGNHPRVVLTEPLDYDRLVAAMRACTLLLTDSGGLQEEAPALGKPVL
CCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCEE
VLRRTTERPEAVEAGTAKLVGTDPEMIVTETASLLDDSSAYEAMARAVNPFGDGKASGRI
EEEECCCCCCHHHCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEE
LEASCAFLGV
EEECHHHHCC
>Mature Secondary Structure 
AGLPRVTIVLGTRPEAIKLAPVIQAFQACDALTTRVVLTGQHREMVAQVMDLFGLSANH
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHCCCCCC
DLDLMAPLQTLTHVTCAALQGLKDEFKAYPPQLVLVQGDTTTAFAAALAAFYEQIPVGHV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHH
EAGLRTDNLLDPFPEEANRRLISQISQLHFAPTPRSQANLTSSGVVGQIFVTGNTVIDAL
HCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHH
LLMAEQAPPIEFDGLDWAHQRVILATVHRRENWGDRLQDIAEGMRRVLDLHPDTALLLPL
HHHHCCCCCCCCCCCCHHHHEEHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
HRNPTVREPMQALLGNHPRVVLTEPLDYDRLVAAMRACTLLLTDSGGLQEEAPALGKPVL
CCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCEE
VLRRTTERPEAVEAGTAKLVGTDPEMIVTETASLLDDSSAYEAMARAVNPFGDGKASGRI
EEEECCCCCCHHHCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEE
LEASCAFLGV
EEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]