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The map label for this gene is nanE [H]

Identifier: 124022359

GI number: 124022359

Start: 611260

End: 611952

Strand: Direct

Name: nanE [H]

Synonym: P9303_06491

Alternate gene names: 124022359

Gene position: 611260-611952 (Clockwise)

Preceding gene: 124022357

Following gene: 124022361

Centisome position: 22.79

GC content: 54.98

Gene sequence:

>693_bases
ATGTCTTTGCCTGCTTTTGAAACTCTCAGACGGGGGTTGATTGTCTCTGTTCAGGCGCCCGAGGGTTCACCGATGCGTCA
TCCTCAGGTGATTGCGGCCATGGCTGAAGCCAGTCTTTGCAATGGCGCGGTTGGGGTGCGTTTGGAAAGTCCGGAACACA
TTGGTGCCGTTCGACGCCGTTGTCCGGATGCCTTGATTATTGGGCTTTGGAAGCGTTCCTTCCCTGATAGTGCTGTCTAC
ATCACGCCAGGATGGGAGGAGGTTCAGGCTGTCTGGTCGGCGGGAGCAGATGTCGTGGCTCTCGATGCTACCCAGCGTCA
TCGGCCAGGGGGGATCACTCTTGAGCAGCTTGTGAGTCGGGTTCGGGAAGAGTTGGGACCCCCTCTGATGGCAGATGTCG
ATACGATTGAGAATGGTTTACTTGCAGCAGAGCTTGGTTGCAGCTTTGTGGGCACCACTCTTTATGGCTATACCGAAGTG
ACTGCTGTTAAGCGGCCTCCGGGTTTGTGTTTGTTGGGGCCGTTGCGGCAGCAGCTTGATTCAGATGTCAAGCTCATCTG
CGAAGGCGGGCTTGATTCTCCTCAGATAGCACTAGAAGCATTGTCTTCAGGTGCAGACATGGTGGTAGTCGGTACAGCGA
TTACCGGTGTCGACCTGCAGGTGGAAAACTATTGCCGAACATTGGCGGCTTAA

Upstream 100 bases:

>100_bases
ACTCGTTGTCAGTCCTACCTTCCCCTGCTTTTGCTCTAAACCATTTGCCGCATCATTGCTCGCCAATCACGAATGCAAAG
CTGTCGAAGGCATCCTGAGC

Downstream 100 bases:

>100_bases
CTTCCAAAGCTTTTTGGCATCAACCGAACTGTGGGACGTGCTTTGGGTCGTGACTTGTCCAGGCAGATGCAGATGCACAA
CGCATGAGACTTGTCCATGC

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSLPAFETLRRGLIVSVQAPEGSPMRHPQVIAAMAEASLCNGAVGVRLESPEHIGAVRRRCPDALIIGLWKRSFPDSAVY
ITPGWEEVQAVWSAGADVVALDATQRHRPGGITLEQLVSRVREELGPPLMADVDTIENGLLAAELGCSFVGTTLYGYTEV
TAVKRPPGLCLLGPLRQQLDSDVKLICEGGLDSPQIALEALSSGADMVVVGTAITGVDLQVENYCRTLAA

Sequences:

>Translated_230_residues
MSLPAFETLRRGLIVSVQAPEGSPMRHPQVIAAMAEASLCNGAVGVRLESPEHIGAVRRRCPDALIIGLWKRSFPDSAVY
ITPGWEEVQAVWSAGADVVALDATQRHRPGGITLEQLVSRVREELGPPLMADVDTIENGLLAAELGCSFVGTTLYGYTEV
TAVKRPPGLCLLGPLRQQLDSDVKLICEGGLDSPQIALEALSSGADMVVVGTAITGVDLQVENYCRTLAA
>Mature_229_residues
SLPAFETLRRGLIVSVQAPEGSPMRHPQVIAAMAEASLCNGAVGVRLESPEHIGAVRRRCPDALIIGLWKRSFPDSAVYI
TPGWEEVQAVWSAGADVVALDATQRHRPGGITLEQLVSRVREELGPPLMADVDTIENGLLAAELGCSFVGTTLYGYTEVT
AVKRPPGLCLLGPLRQQLDSDVKLICEGGLDSPQIALEALSSGADMVVVGTAITGVDLQVENYCRTLAA

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=215, Percent_Identity=39.0697674418605, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 24413; Mature: 24282

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPAFETLRRGLIVSVQAPEGSPMRHPQVIAAMAEASLCNGAVGVRLESPEHIGAVRRR
CCCCHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
CPDALIIGLWKRSFPDSAVYITPGWEEVQAVWSAGADVVALDATQRHRPGGITLEQLVSR
CCHHEEEHHHHCCCCCCEEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHH
VREELGPPLMADVDTIENGLLAAELGCSFVGTTLYGYTEVTAVKRPPGLCLLGPLRQQLD
HHHHHCCCCEECHHHHHCCEEEHHHCCHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHCC
SDVKLICEGGLDSPQIALEALSSGADMVVVGTAITGVDLQVENYCRTLAA
CCEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEEECCEEEHHHHHHHHCC
>Mature Secondary Structure 
SLPAFETLRRGLIVSVQAPEGSPMRHPQVIAAMAEASLCNGAVGVRLESPEHIGAVRRR
CCCHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
CPDALIIGLWKRSFPDSAVYITPGWEEVQAVWSAGADVVALDATQRHRPGGITLEQLVSR
CCHHEEEHHHHCCCCCCEEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHH
VREELGPPLMADVDTIENGLLAAELGCSFVGTTLYGYTEVTAVKRPPGLCLLGPLRQQLD
HHHHHCCCCEECHHHHHCCEEEHHHCCHHHHHHHHCCEEEEEECCCCCEEEEHHHHHHCC
SDVKLICEGGLDSPQIALEALSSGADMVVVGTAITGVDLQVENYCRTLAA
CCEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEEECCEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA