Click here to switch to the map view.

The map label for this gene is cysQ [H]

Identifier: 124022311

GI number: 124022311

Start: 567322

End: 568326

Strand: Direct

Name: cysQ [H]

Synonym: P9303_06011

Alternate gene names: 124022311

Gene position: 567322-568326 (Clockwise)

Preceding gene: 124022308

Following gene: 124022326

Centisome position: 21.15

GC content: 56.52

Gene sequence:

>1005_bases
GTGACCAATGGGCGTCCCAACCACATAGAGCACCCCTGGTGCTGGTTCCTCTCGCTGGCTCAAAATGAGGCTTGCACGTG
TCTATTCATGATGCCGAATGCACCTCTTCTCCCTGTTGGTGTGGACCTGGAGGTTTTGTTGCAGCAATTGAGGCGATTGA
GCTGGGGTGCTGCAGACATCCTGCTGGCCTATGCCCGGGGAGAACAGCCACCGCATGGATTTTCTAAGGCTCTGAGTGTT
GACGATGGTGGTGAGGGGCCTGTCTCTGCCGCTGACCTTGCGGTGAACCGTTGGCTTCTGGATGGCTTAGAAGCGAATTT
CCCCTTGGCAGATTGGACTCTATTGAGTGAGGAGACGGCAAAGGAGCAACTCACTGAAGGCGAACCCTTAGCGGCGGAAT
GGTTGTGGATCCTTGACCCCTTGGATGGCACAAAGGACTTCTTGCAGGGCACAGGTGAATACGCCGTGCATCTTGCCTTG
GTGCATGGTCAACGACCAGTGCTTGGCGTGGTACTCCTGCCAGAAGCCGAGGAGCTTTGGTTCGGTGTGATCGGTTCTGG
TGCCTGGTGCGAAGACCGGCAGGGACAACGTTCGCCGGTGCGTTTTAGTCAGCGCAAGGCTTTTGGTGAGTTGATGCTGG
TAGCGAGTCGCAACCACCGCGACAACAGGCTTGAACAGCTGCTAGAGAGTCTTGCTCTTGGTGGTAGCAAGGCTGTGGGC
AGTGTTGGTTGCAAGGTAACCACGATTCTGCGCGGAGAAACAGATCTGTATGTCTCTCTTTCAGGCCGTAGTGCTCCAAA
AGACTGGGATATGGCTGCTCCAGAGGCGGTGCTGATGGCTGCAGGGGGATGTTTCACTCATGCTGATGGACGCCAGCTTG
CTTACAACAGCGGTGATGTGCGTCAGGCCGGATGTTTGATCGCCAGCCATGGCCTCGCCCACGCCCAGCTTTGTGAAGCA
GCGGCGCGGGCTATGGAAGAGATCGACCCAGGCTTTCAGGTTTGA

Upstream 100 bases:

>100_bases
CCAGGCTGTTGAGTAGATGGCCGCTATGGCGTGTGTCTTCACAGGCGATGGCCGAGACATTCTTGAGCACAGAGCGTGCT
CTGGGGGAAAGATCTCCGAG

Downstream 100 bases:

>100_bases
ATTGACCTGTACCCCCTCAGTTGAGAGGGGCTACAGGAGTTGGAGCTGGCTCTGATTGAGTCTCTTCGCCGTTCTGAGGG
ACGCCTCTGAGTGTGAGGTT

Product: CysQ

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTNGRPNHIEHPWCWFLSLAQNEACTCLFMMPNAPLLPVGVDLEVLLQQLRRLSWGAADILLAYARGEQPPHGFSKALSV
DDGGEGPVSAADLAVNRWLLDGLEANFPLADWTLLSEETAKEQLTEGEPLAAEWLWILDPLDGTKDFLQGTGEYAVHLAL
VHGQRPVLGVVLLPEAEELWFGVIGSGAWCEDRQGQRSPVRFSQRKAFGELMLVASRNHRDNRLEQLLESLALGGSKAVG
SVGCKVTTILRGETDLYVSLSGRSAPKDWDMAAPEAVLMAAGGCFTHADGRQLAYNSGDVRQAGCLIASHGLAHAQLCEA
AARAMEEIDPGFQV

Sequences:

>Translated_334_residues
MTNGRPNHIEHPWCWFLSLAQNEACTCLFMMPNAPLLPVGVDLEVLLQQLRRLSWGAADILLAYARGEQPPHGFSKALSV
DDGGEGPVSAADLAVNRWLLDGLEANFPLADWTLLSEETAKEQLTEGEPLAAEWLWILDPLDGTKDFLQGTGEYAVHLAL
VHGQRPVLGVVLLPEAEELWFGVIGSGAWCEDRQGQRSPVRFSQRKAFGELMLVASRNHRDNRLEQLLESLALGGSKAVG
SVGCKVTTILRGETDLYVSLSGRSAPKDWDMAAPEAVLMAAGGCFTHADGRQLAYNSGDVRQAGCLIASHGLAHAQLCEA
AARAMEEIDPGFQV
>Mature_333_residues
TNGRPNHIEHPWCWFLSLAQNEACTCLFMMPNAPLLPVGVDLEVLLQQLRRLSWGAADILLAYARGEQPPHGFSKALSVD
DGGEGPVSAADLAVNRWLLDGLEANFPLADWTLLSEETAKEQLTEGEPLAAEWLWILDPLDGTKDFLQGTGEYAVHLALV
HGQRPVLGVVLLPEAEELWFGVIGSGAWCEDRQGQRSPVRFSQRKAFGELMLVASRNHRDNRLEQLLESLALGGSKAVGS
VGCKVTTILRGETDLYVSLSGRSAPKDWDMAAPEAVLMAAGGCFTHADGRQLAYNSGDVRQAGCLIASHGLAHAQLCEAA
ARAMEEIDPGFQV

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=214, Percent_Identity=31.3084112149533, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71995897, Length=250, Percent_Identity=28.8, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71995905, Length=250, Percent_Identity=28.8, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24651149, Length=267, Percent_Identity=30.3370786516854, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24664922, Length=224, Percent_Identity=25.8928571428571, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24664926, Length=229, Percent_Identity=27.0742358078603, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 36188; Mature: 36057

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNGRPNHIEHPWCWFLSLAQNEACTCLFMMPNAPLLPVGVDLEVLLQQLRRLSWGAADI
CCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHCCCHHHH
LLAYARGEQPPHGFSKALSVDDGGEGPVSAADLAVNRWLLDGLEANFPLADWTLLSEETA
HHHHHCCCCCCCCHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHH
KEQLTEGEPLAAEWLWILDPLDGTKDFLQGTGEYAVHLALVHGQRPVLGVVLLPEAEELW
HHHHCCCCCCCEEEEEEECCCCCCHHHHHCCCCEEEEEEEEECCCCEEEEEECCCHHHHE
FGVIGSGAWCEDRQGQRSPVRFSQRKAFGELMLVASRNHRDNRLEQLLESLALGGSKAVG
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
SVGCKVTTILRGETDLYVSLSGRSAPKDWDMAAPEAVLMAAGGCFTHADGRQLAYNSGDV
CCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCEECCCCCEEEECCCCC
RQAGCLIASHGLAHAQLCEAAARAMEEIDPGFQV
HHHCEEEECCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TNGRPNHIEHPWCWFLSLAQNEACTCLFMMPNAPLLPVGVDLEVLLQQLRRLSWGAADI
CCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHCCCHHHH
LLAYARGEQPPHGFSKALSVDDGGEGPVSAADLAVNRWLLDGLEANFPLADWTLLSEETA
HHHHHCCCCCCCCHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHH
KEQLTEGEPLAAEWLWILDPLDGTKDFLQGTGEYAVHLALVHGQRPVLGVVLLPEAEELW
HHHHCCCCCCCEEEEEEECCCCCCHHHHHCCCCEEEEEEEEECCCCEEEEEECCCHHHHE
FGVIGSGAWCEDRQGQRSPVRFSQRKAFGELMLVASRNHRDNRLEQLLESLALGGSKAVG
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
SVGCKVTTILRGETDLYVSLSGRSAPKDWDMAAPEAVLMAAGGCFTHADGRQLAYNSGDV
CCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCEECCCCCEEEECCCCC
RQAGCLIASHGLAHAQLCEAAARAMEEIDPGFQV
HHHCEEEECCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]