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The map label for this gene is kaiC [H]

Identifier: 124022254

GI number: 124022254

Start: 524817

End: 526283

Strand: Direct

Name: kaiC [H]

Synonym: P9303_05441

Alternate gene names: 124022254

Gene position: 524817-526283 (Clockwise)

Preceding gene: 124022253

Following gene: 124022257

Centisome position: 19.56

GC content: 47.72

Gene sequence:

>1467_bases
ATGCAGGTGCAGAAGCTGCCTACTGGGATCGAAGGTTTTGATGACATCTGTCATGGCGGCTTGCCGACGGGGCGAAGCAC
GCTGATCAGTGGCACGTCGGGAACAGGTAAGACAGTCTTTTCACTTCATTTTTTGCACAACGGCATTACCCAGTTCGATG
AGCCGGGAATCTTCGTGACCTTCGAAGAGTCGCCATCAGATATTTTGCGAAATTCCGCCAGCTTTGGTTGGAATCTTCAA
GAGATGGTGGAGCAGGATAAATTATTCATACTCGATGCTTCACCGGATCCTGATGGTCAGGATGTTGCAGGCAGCTTTGA
TCTTTCAGGGTTAATTGAAAGGATTAATTACGCCATTGTTAAATATAAAGCGAAACGGGTCGCAATCGATTCCATGACAG
CTGTTTTCCAACAGTACGACGCTATTTCTGTGGTGCGTAGGGAAATCTTTCGCTTGATTGCACGTCTTAAGGTGATTGGT
GTTACCACCGTAATGACCACGGAACGGATTGATGAATATGGCCCAATTGCACGCTATGGGGTAGAGGAGTTTGTTTCCGA
CAACGTCGTTATCCTACGCAATGTTCTTGAGACTGAGAAGCGTCGACGTACCGTTGAGATTCTCAAGTTACGTGGCACAA
CTCACATGAAGGGTGAGTTTCCATTCACCATGGGCACCCACGGCGTCAGCGTCTTTCCTTTAGGCGCAATGCGGCTTACG
CAGCGTTCCTCCAACGTGCGGATTAGTTCTGGTGTGCCTCATCTTGATGAGATGTGTGGTGGAGGGTTCTTCAAGGATTC
GATCATTCTTGTTACTGGTGCAACGGGCACTGGTAAAACCCTTTTGGTGTCGAAGTTTATTGAGGATGCTTTCCGAAATA
AGGAACGCGCGGTTTTGTTTGCCTATGAGGAGTCGCGAGCCCAGCTGCTGCGTAATGCCACCAGTTGGGGGATTGATTTT
GAAGAGATGGAAAGTGAAGGCCTGTTGAAGATTATTTGTGCTTATCCCGAGTCGACCGGTCTAGAAGATCATCTGGAGAT
TATTAAAACGGAGATTGGACAATTCAAGCCATCGAGGATGGCGATTGATTCACTTTCGGCCCTTGCACGTGGCGTGAGTC
TCAACGCCTTTAGGCAGTTTGTGATTGGAGTAACAGGCTATGCAAAGCAGGAGGAAATAGCGGGATTCTTTACCAATACC
GCTGAAGAGTTTATGGGAAGTCATTCGATTACCGACTCCCATATCTCCACAATCACAGATACTATTCTGCTGCTTCAGTA
TGTGGAGATCCGCGGCGAGATGGCCAGAGCTGTGAATGTATTTAAGATGCGTGGCTCCTGGCACGACAAGAGAATTCGTG
AGTATGTTATTACTGATAATGGCCCACAGATTAAAGACTCATTCTCTAACTTCGAACGGATCTTCAGTGGTGCTCCTCAT
CGTATTGCTGACGACGAACGCTCTTAA

Upstream 100 bases:

>100_bases
AGGCTCGCGGTGCAGCGCTTTGTTCCATGGCTGATTCTCTCTAGCGTTTGAGTAGAACGTCCTAGCTATGCAGTCTTCTA
GTGCCGGTGGCCCCTCCCAG

Downstream 100 bases:

>100_bases
TGTTGCTTCGATGCCAAGGGCCTTTAAAATGCTAGCTGATTCAGGTTATTGGCTGAATTAGAGTTCTAAACCTTGTTCTT
GTTGCCGAGTTGTTCGTACT

Product: circadian clock protein KaiC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MQVQKLPTGIEGFDDICHGGLPTGRSTLISGTSGTGKTVFSLHFLHNGITQFDEPGIFVTFEESPSDILRNSASFGWNLQ
EMVEQDKLFILDASPDPDGQDVAGSFDLSGLIERINYAIVKYKAKRVAIDSMTAVFQQYDAISVVRREIFRLIARLKVIG
VTTVMTTERIDEYGPIARYGVEEFVSDNVVILRNVLETEKRRRTVEILKLRGTTHMKGEFPFTMGTHGVSVFPLGAMRLT
QRSSNVRISSGVPHLDEMCGGGFFKDSIILVTGATGTGKTLLVSKFIEDAFRNKERAVLFAYEESRAQLLRNATSWGIDF
EEMESEGLLKIICAYPESTGLEDHLEIIKTEIGQFKPSRMAIDSLSALARGVSLNAFRQFVIGVTGYAKQEEIAGFFTNT
AEEFMGSHSITDSHISTITDTILLLQYVEIRGEMARAVNVFKMRGSWHDKRIREYVITDNGPQIKDSFSNFERIFSGAPH
RIADDERS

Sequences:

>Translated_488_residues
MQVQKLPTGIEGFDDICHGGLPTGRSTLISGTSGTGKTVFSLHFLHNGITQFDEPGIFVTFEESPSDILRNSASFGWNLQ
EMVEQDKLFILDASPDPDGQDVAGSFDLSGLIERINYAIVKYKAKRVAIDSMTAVFQQYDAISVVRREIFRLIARLKVIG
VTTVMTTERIDEYGPIARYGVEEFVSDNVVILRNVLETEKRRRTVEILKLRGTTHMKGEFPFTMGTHGVSVFPLGAMRLT
QRSSNVRISSGVPHLDEMCGGGFFKDSIILVTGATGTGKTLLVSKFIEDAFRNKERAVLFAYEESRAQLLRNATSWGIDF
EEMESEGLLKIICAYPESTGLEDHLEIIKTEIGQFKPSRMAIDSLSALARGVSLNAFRQFVIGVTGYAKQEEIAGFFTNT
AEEFMGSHSITDSHISTITDTILLLQYVEIRGEMARAVNVFKMRGSWHDKRIREYVITDNGPQIKDSFSNFERIFSGAPH
RIADDERS
>Mature_488_residues
MQVQKLPTGIEGFDDICHGGLPTGRSTLISGTSGTGKTVFSLHFLHNGITQFDEPGIFVTFEESPSDILRNSASFGWNLQ
EMVEQDKLFILDASPDPDGQDVAGSFDLSGLIERINYAIVKYKAKRVAIDSMTAVFQQYDAISVVRREIFRLIARLKVIG
VTTVMTTERIDEYGPIARYGVEEFVSDNVVILRNVLETEKRRRTVEILKLRGTTHMKGEFPFTMGTHGVSVFPLGAMRLT
QRSSNVRISSGVPHLDEMCGGGFFKDSIILVTGATGTGKTLLVSKFIEDAFRNKERAVLFAYEESRAQLLRNATSWGIDF
EEMESEGLLKIICAYPESTGLEDHLEIIKTEIGQFKPSRMAIDSLSALARGVSLNAFRQFVIGVTGYAKQEEIAGFFTNT
AEEFMGSHSITDSHISTITDTILLLQYVEIRGEMARAVNVFKMRGSWHDKRIREYVITDNGPQIKDSFSNFERIFSGAPH
RIADDERS

Specific function: Core component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by actin

COG id: COG0467

COG function: function code T; RecA-superfamily ATPases implicated in signal transduction

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 kaiC domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014774
- InterPro:   IPR013503
- InterPro:   IPR010624 [H]

Pfam domain/function: PF06745 KaiC [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 54437; Mature: 54437

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS51146 KAIC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVQKLPTGIEGFDDICHGGLPTGRSTLISGTSGTGKTVFSLHFLHNGITQFDEPGIFVT
CCCCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCEEEHHHHHCCCHHCCCCCEEEE
FEESPSDILRNSASFGWNLQEMVEQDKLFILDASPDPDGQDVAGSFDLSGLIERINYAIV
ECCCHHHHHHCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
KYKAKRVAIDSMTAVFQQYDAISVVRREIFRLIARLKVIGVTTVMTTERIDEYGPIARYG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VEEFVSDNVVILRNVLETEKRRRTVEILKLRGTTHMKGEFPFTMGTHGVSVFPLGAMRLT
HHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEECCCCCEEEECCHHHHH
QRSSNVRISSGVPHLDEMCGGGFFKDSIILVTGATGTGKTLLVSKFIEDAFRNKERAVLF
HCCCCEEEECCCCCHHHHHCCCEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEE
AYEESRAQLLRNATSWGIDFEEMESEGLLKIICAYPESTGLEDHLEIIKTEIGQFKPSRM
EEHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHH
AIDSLSALARGVSLNAFRQFVIGVTGYAKQEEIAGFFTNTAEEFMGSHSITDSHISTITD
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
TILLLQYVEIRGEMARAVNVFKMRGSWHDKRIREYVITDNGPQIKDSFSNFERIFSGAPH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCHHHHHHHHHHHHCCCCC
RIADDERS
CCCCCCCC
>Mature Secondary Structure
MQVQKLPTGIEGFDDICHGGLPTGRSTLISGTSGTGKTVFSLHFLHNGITQFDEPGIFVT
CCCCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCEEEHHHHHCCCHHCCCCCEEEE
FEESPSDILRNSASFGWNLQEMVEQDKLFILDASPDPDGQDVAGSFDLSGLIERINYAIV
ECCCHHHHHHCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
KYKAKRVAIDSMTAVFQQYDAISVVRREIFRLIARLKVIGVTTVMTTERIDEYGPIARYG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VEEFVSDNVVILRNVLETEKRRRTVEILKLRGTTHMKGEFPFTMGTHGVSVFPLGAMRLT
HHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEECCCCCEEEECCHHHHH
QRSSNVRISSGVPHLDEMCGGGFFKDSIILVTGATGTGKTLLVSKFIEDAFRNKERAVLF
HCCCCEEEECCCCCHHHHHCCCEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEE
AYEESRAQLLRNATSWGIDFEEMESEGLLKIICAYPESTGLEDHLEIIKTEIGQFKPSRM
EEHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHH
AIDSLSALARGVSLNAFRQFVIGVTGYAKQEEIAGFFTNTAEEFMGSHSITDSHISTITD
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
TILLLQYVEIRGEMARAVNVFKMRGSWHDKRIREYVITDNGPQIKDSFSNFERIFSGAPH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCHHHHHHHHHHHHCCCCC
RIADDERS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917641 [H]