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The map label for this gene is zwf [H]

Identifier: 123968713

GI number: 123968713

Start: 994280

End: 995803

Strand: Reverse

Name: zwf [H]

Synonym: A9601_11801

Alternate gene names: 123968713

Gene position: 995803-994280 (Counterclockwise)

Preceding gene: 123968714

Following gene: 123968712

Centisome position: 59.63

GC content: 34.91

Gene sequence:

>1524_bases
ATGCCTTCAACTTTAAGTAATCCTCTAAGATTAGGTTTACGGCAGGAAAGAGTCATATCTCCACAATCTTTAGTAATTTT
TGGCGCTAGTGGAGACCTTACTCATAGAAAATTAATACCAGCCTTATTTGAACTCTATTTGCAAAGAAGAATTCCTAGTG
AATTTGGAATAGTTGGTTGTGCGAGAAGACCTTGGACTGATTATGAGTTTAGAGAAAAGATGAAAGTAAAGTTATCAAAT
CAAATATCTGGTAAAGAAAGGGAGTGGGAACAATTTTCTAATTATCTTTTCTATGAACCAGTTGACTTACAAGAAAGTGA
TCATGTCGTAAGGCTTTCTAGAAGATTAAATGAAATTGATAAAACACAAGCTACTCATGGGAATAGAACATTTTATTTAT
CAGTATCTCCAAATTTCTATGCAAGTGGATGTAAAGCTCTAAAAGGAGCTGGCCTTTTAGATAACCCTAAGAAAAGTCGT
TTGGTAATTGAAAAACCTTTTGGCAGAGATTATTCAAGTGCAAAAAAATTGAATAAGATTGTTCAAAGTTGCGCTGAAGA
AAGTCAGATTTATAGGATTGATCATTATTTAGGTAAAGAGACAGTTCAGAATATTCTTGTTTTGAGGTTTGCTAATACTA
TTTTTGAACCAATTTGGAACAGGAATTATATATCAAGTGTTCAAATTACTTCATCTGAAACAGTTGGTGTTGAAGATAGA
GCAGGTTATTACGAAAGCTCTGGTGCTTTGCGGGATATGCTTCAAAATCATATGACTCAAATGCTTGCAGTTACTGCAAT
GGAACCTCCTGGAAAATTTGAACCAGAAGCAATAAGAAATGAAAAAGCTAAGGTTCTTCAAGCTTCCAAACTTGCTGACG
AAAATCAACCGTGGAATTGTTGCATAAGAGGACAATATGGAGAGGGAGGGAATATTTCAAATCGACTCAAAGGATATAGG
CAGGAAGATGGTGTTAATAGTAACAGCACAACAGAAACTTATATCGCGACAAAAGTTTTCGTTGATAACTGGCGTTGGCA
AGGAGTGCCTTTTTATTTGAGAACTGGTAAAAGACTACCTAAAAGACTTGGAGAAATAGTCTTGACTTTTAAAGATGTTC
CTGTTCATTTATTTGAATCAACAATAATAAATCCTGCCCCAAATCAACTTATCCTTAGAATTCAGCCAAATGAAGGTGCT
ACTTTCAAATTTGAGGTAAAATCTCCTGGTTCTGGAATGAAATCAAGACCTGTTGAAATGGAATTTTCTTATGATGAATC
ATTTGGAGAACCATCAGATGAAGGCTATGTAAGATTATTAGCTGATGCAATGCTTTCTGACCCAACATTATTTACCCGTA
GTGATGAGGTAGAGGCAGCCTGGAAACTTTATACGCCATTAATAGAATTGATGGATAATTCTCCTTGGAAGTTACCTATT
TATAATTATGAATCTATGACATGGGGACCTCCTGAGTCAGATCAATTAATTTCAAAAGATAATATTTTCTGGCGTAGACC
CTAA

Upstream 100 bases:

>100_bases
CTTAGATTTAAGTTTCACTTATTAAATACTTTTTGGTTTAGACACAATATGTAGCTAATTTTTGAAAAAAAGAGGATTTT
AAATAAAGAATACTAAGAAT

Downstream 100 bases:

>100_bases
AAATGAAACCTCAACTTACACTTCAAACCCCTTTAGAGCTGCCTTATCAGGAAATTTCTAATTACCTTAATAAATTATGG
ATTTCAGAAGATAAAGATAA

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MPSTLSNPLRLGLRQERVISPQSLVIFGASGDLTHRKLIPALFELYLQRRIPSEFGIVGCARRPWTDYEFREKMKVKLSN
QISGKEREWEQFSNYLFYEPVDLQESDHVVRLSRRLNEIDKTQATHGNRTFYLSVSPNFYASGCKALKGAGLLDNPKKSR
LVIEKPFGRDYSSAKKLNKIVQSCAEESQIYRIDHYLGKETVQNILVLRFANTIFEPIWNRNYISSVQITSSETVGVEDR
AGYYESSGALRDMLQNHMTQMLAVTAMEPPGKFEPEAIRNEKAKVLQASKLADENQPWNCCIRGQYGEGGNISNRLKGYR
QEDGVNSNSTTETYIATKVFVDNWRWQGVPFYLRTGKRLPKRLGEIVLTFKDVPVHLFESTIINPAPNQLILRIQPNEGA
TFKFEVKSPGSGMKSRPVEMEFSYDESFGEPSDEGYVRLLADAMLSDPTLFTRSDEVEAAWKLYTPLIELMDNSPWKLPI
YNYESMTWGPPESDQLISKDNIFWRRP

Sequences:

>Translated_507_residues
MPSTLSNPLRLGLRQERVISPQSLVIFGASGDLTHRKLIPALFELYLQRRIPSEFGIVGCARRPWTDYEFREKMKVKLSN
QISGKEREWEQFSNYLFYEPVDLQESDHVVRLSRRLNEIDKTQATHGNRTFYLSVSPNFYASGCKALKGAGLLDNPKKSR
LVIEKPFGRDYSSAKKLNKIVQSCAEESQIYRIDHYLGKETVQNILVLRFANTIFEPIWNRNYISSVQITSSETVGVEDR
AGYYESSGALRDMLQNHMTQMLAVTAMEPPGKFEPEAIRNEKAKVLQASKLADENQPWNCCIRGQYGEGGNISNRLKGYR
QEDGVNSNSTTETYIATKVFVDNWRWQGVPFYLRTGKRLPKRLGEIVLTFKDVPVHLFESTIINPAPNQLILRIQPNEGA
TFKFEVKSPGSGMKSRPVEMEFSYDESFGEPSDEGYVRLLADAMLSDPTLFTRSDEVEAAWKLYTPLIELMDNSPWKLPI
YNYESMTWGPPESDQLISKDNIFWRRP
>Mature_506_residues
PSTLSNPLRLGLRQERVISPQSLVIFGASGDLTHRKLIPALFELYLQRRIPSEFGIVGCARRPWTDYEFREKMKVKLSNQ
ISGKEREWEQFSNYLFYEPVDLQESDHVVRLSRRLNEIDKTQATHGNRTFYLSVSPNFYASGCKALKGAGLLDNPKKSRL
VIEKPFGRDYSSAKKLNKIVQSCAEESQIYRIDHYLGKETVQNILVLRFANTIFEPIWNRNYISSVQITSSETVGVEDRA
GYYESSGALRDMLQNHMTQMLAVTAMEPPGKFEPEAIRNEKAKVLQASKLADENQPWNCCIRGQYGEGGNISNRLKGYRQ
EDGVNSNSTTETYIATKVFVDNWRWQGVPFYLRTGKRLPKRLGEIVLTFKDVPVHLFESTIINPAPNQLILRIQPNEGAT
FKFEVKSPGSGMKSRPVEMEFSYDESFGEPSDEGYVRLLADAMLSDPTLFTRSDEVEAAWKLYTPLIELMDNSPWKLPIY
NYESMTWGPPESDQLISKDNIFWRRP

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=483, Percent_Identity=36.6459627329193, Blast_Score=285, Evalue=7e-77,
Organism=Homo sapiens, GI109389365, Length=483, Percent_Identity=36.6459627329193, Blast_Score=285, Evalue=7e-77,
Organism=Homo sapiens, GI52145310, Length=499, Percent_Identity=28.2565130260521, Blast_Score=169, Evalue=6e-42,
Organism=Escherichia coli, GI1788158, Length=490, Percent_Identity=38.1632653061225, Blast_Score=338, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI17538218, Length=487, Percent_Identity=34.4969199178645, Blast_Score=298, Evalue=7e-81,
Organism=Saccharomyces cerevisiae, GI6324088, Length=472, Percent_Identity=34.3220338983051, Blast_Score=266, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24643350, Length=490, Percent_Identity=34.6938775510204, Blast_Score=278, Evalue=8e-75,
Organism=Drosophila melanogaster, GI24643352, Length=490, Percent_Identity=34.6938775510204, Blast_Score=278, Evalue=9e-75,
Organism=Drosophila melanogaster, GI221513548, Length=466, Percent_Identity=28.5407725321888, Blast_Score=194, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 58139; Mature: 58007

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTLSNPLRLGLRQERVISPQSLVIFGASGDLTHRKLIPALFELYLQRRIPSEFGIVGC
CCCCCCCHHHHCCCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHCEEEC
ARRPWTDYEFREKMKVKLSNQISGKEREWEQFSNYLFYEPVDLQESDHVVRLSRRLNEID
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHHHH
KTQATHGNRTFYLSVSPNFYASGCKALKGAGLLDNPKKSRLVIEKPFGRDYSSAKKLNKI
HHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHH
VQSCAEESQIYRIDHYLGKETVQNILVLRFANTIFEPIWNRNYISSVQITSSETVGVEDR
HHHHHHHCCEEEHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
AGYYESSGALRDMLQNHMTQMLAVTAMEPPGKFEPEAIRNEKAKVLQASKLADENQPWNC
CCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
CIRGQYGEGGNISNRLKGYRQEDGVNSNSTTETYIATKVFVDNWRWQGVPFYLRTGKRLP
EEECCCCCCCCHHHHHCCCHHHCCCCCCCCCEEEEEEEEEEECCEECCCCCEECCCHHHH
KRLGEIVLTFKDVPVHLFESTIINPAPNQLILRIQPNEGATFKFEVKSPGSGMKSRPVEM
HHHHHEEEEECCCCHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCEEE
EFSYDESFGEPSDEGYVRLLADAMLSDPTLFTRSDEVEAAWKLYTPLIELMDNSPWKLPI
EECCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEE
YNYESMTWGPPESDQLISKDNIFWRRP
ECCCCCCCCCCCCCCEECCCCEEEECC
>Mature Secondary Structure 
PSTLSNPLRLGLRQERVISPQSLVIFGASGDLTHRKLIPALFELYLQRRIPSEFGIVGC
CCCCCCHHHHCCCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHCEEEC
ARRPWTDYEFREKMKVKLSNQISGKEREWEQFSNYLFYEPVDLQESDHVVRLSRRLNEID
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHHHH
KTQATHGNRTFYLSVSPNFYASGCKALKGAGLLDNPKKSRLVIEKPFGRDYSSAKKLNKI
HHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHH
VQSCAEESQIYRIDHYLGKETVQNILVLRFANTIFEPIWNRNYISSVQITSSETVGVEDR
HHHHHHHCCEEEHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
AGYYESSGALRDMLQNHMTQMLAVTAMEPPGKFEPEAIRNEKAKVLQASKLADENQPWNC
CCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
CIRGQYGEGGNISNRLKGYRQEDGVNSNSTTETYIATKVFVDNWRWQGVPFYLRTGKRLP
EEECCCCCCCCHHHHHCCCHHHCCCCCCCCCEEEEEEEEEEECCEECCCCCEECCCHHHH
KRLGEIVLTFKDVPVHLFESTIINPAPNQLILRIQPNEGATFKFEVKSPGSGMKSRPVEM
HHHHHEEEEECCCCHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCEEE
EFSYDESFGEPSDEGYVRLLADAMLSDPTLFTRSDEVEAAWKLYTPLIELMDNSPWKLPI
EECCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEE
YNYESMTWGPPESDQLISKDNIFWRRP
ECCCCCCCCCCCCCCEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1643289 [H]