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The map label for this gene is ecm27 [H]

Identifier: 123968159

GI number: 123968159

Start: 545817

End: 546896

Strand: Reverse

Name: ecm27 [H]

Synonym: A9601_06241

Alternate gene names: 123968159

Gene position: 546896-545817 (Counterclockwise)

Preceding gene: 123968164

Following gene: 123968157

Centisome position: 32.75

GC content: 30.65

Gene sequence:

>1080_bases
ATGAATGATTTTTTATTTCCAATAATAGAAATAGTTTTAGGCATAGTTCTACTTTTTTCTGGAGGGGAGTTTTTTATTCA
AGGAGCCATATTTTTATCTTTAATTTTAGGAATACCTCAAATAGTAATTGGTTTGACAGTTGTTTCTCTAGGGACAAGCT
CTCCTGAGTTGTTGGTAAGTTTGAGTTCAATTTTAAAAGGCAGTGATTCGCTTGCGGCAAGCAATGTAATTGGAAGCAAT
ATTTTTAATGTTCTCATTGTTTTGGGCATAAGCTCATTGATAACACCTCTTAAGGTAAAAAGCAGAATAGTAAGAAGAGA
TGTGCCTCTTTTAATGGCAATTTCTTGTGCAGTTTGGGCCATGTCATCAACAGGCTTATTAACATTGCAAGCAGGGGTAT
TTCTAATATTTTGTTTAATCTTAAATACAATATGGGAAATAAATACTATGAATGAGAAAGGAGAGGAGACAAAAGACGCT
GAACCTGAGATAGAAGAATTAAAAGATAACCATAAAGGGAAGCTTAATATTTTACTAAAGTTAATATTGGGAATATTTCT
TTTAAGCTTTGGTTCAAATATTTTAGTAAATGGTTCTCAAACGCTTGCTACTCTTTTGGGTGTAAATGAAATTGTTATTG
GTTTAACTATCGTCGCCACTGGGACATCTTTACCAGAATTAGTAACTTCAATAATTGCTGCATTTAAAGGCAAAACAGAT
CTTGCAATTGGGAATGTAATAGGAAGTAATTTACTAAATCAACTTTTAATCCTTGGAAGTTGCAGTATTTTTTCAGGATT
TAAAGGTTTAGTAATTGAACAGAGTCTAATAAAAGTTGACTTACCTTTTATGGTTTTAACTACCTTTGCATGCTTACCAA
TTTTCTGGAGCAAAGGGAAAATCACAAGAATTGAAGGATTTATTTTGCTTAATCTTTATATTTTCTACATTCTCGATAAG
ATACTTTTCCTGAATGAATTTAACTTCCTTTCTGAATTAAGGATAGGTTTATTTATTTACTTTGCATTACTTATAACATT
TCTGATTCTTCAAGAAAAATTAAAATTTTCTAATTCATAA

Upstream 100 bases:

>100_bases
ATTTTAACAGCAAATTAAAATTGACAATCAATTATAGATATTCGAGGATAGTTATTAACCAATTAAGAAAATTTTTATTA
TCTAAATAAAAACCCTAAAT

Downstream 100 bases:

>100_bases
TTTTATCCATACATAGTCACAAATTCTTCTGAGATAGTTGGATGCAAAGCCATAGTAATATCAAAGTCTTTTTTTGTTAT
CCCTGCATTTAATGAAATTG

Product: CaCA family sodium/calcium exchanger

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MNDFLFPIIEIVLGIVLLFSGGEFFIQGAIFLSLILGIPQIVIGLTVVSLGTSSPELLVSLSSILKGSDSLAASNVIGSN
IFNVLIVLGISSLITPLKVKSRIVRRDVPLLMAISCAVWAMSSTGLLTLQAGVFLIFCLILNTIWEINTMNEKGEETKDA
EPEIEELKDNHKGKLNILLKLILGIFLLSFGSNILVNGSQTLATLLGVNEIVIGLTIVATGTSLPELVTSIIAAFKGKTD
LAIGNVIGSNLLNQLLILGSCSIFSGFKGLVIEQSLIKVDLPFMVLTTFACLPIFWSKGKITRIEGFILLNLYIFYILDK
ILFLNEFNFLSELRIGLFIYFALLITFLILQEKLKFSNS

Sequences:

>Translated_359_residues
MNDFLFPIIEIVLGIVLLFSGGEFFIQGAIFLSLILGIPQIVIGLTVVSLGTSSPELLVSLSSILKGSDSLAASNVIGSN
IFNVLIVLGISSLITPLKVKSRIVRRDVPLLMAISCAVWAMSSTGLLTLQAGVFLIFCLILNTIWEINTMNEKGEETKDA
EPEIEELKDNHKGKLNILLKLILGIFLLSFGSNILVNGSQTLATLLGVNEIVIGLTIVATGTSLPELVTSIIAAFKGKTD
LAIGNVIGSNLLNQLLILGSCSIFSGFKGLVIEQSLIKVDLPFMVLTTFACLPIFWSKGKITRIEGFILLNLYIFYILDK
ILFLNEFNFLSELRIGLFIYFALLITFLILQEKLKFSNS
>Mature_359_residues
MNDFLFPIIEIVLGIVLLFSGGEFFIQGAIFLSLILGIPQIVIGLTVVSLGTSSPELLVSLSSILKGSDSLAASNVIGSN
IFNVLIVLGISSLITPLKVKSRIVRRDVPLLMAISCAVWAMSSTGLLTLQAGVFLIFCLILNTIWEINTMNEKGEETKDA
EPEIEELKDNHKGKLNILLKLILGIFLLSFGSNILVNGSQTLATLLGVNEIVIGLTIVATGTSLPELVTSIIAAFKGKTD
LAIGNVIGSNLLNQLLILGSCSIFSGFKGLVIEQSLIKVDLPFMVLTTFACLPIFWSKGKITRIEGFILLNLYIFYILDK
ILFLNEFNFLSELRIGLFIYFALLITFLILQEKLKFSNS

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI300797299, Length=247, Percent_Identity=25.9109311740891, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI300797277, Length=247, Percent_Identity=25.9109311740891, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789587, Length=235, Percent_Identity=34.8936170212766, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 39092; Mature: 39092

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFLFPIIEIVLGIVLLFSGGEFFIQGAIFLSLILGIPQIVIGLTVVSLGTSSPELLVS
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LSSILKGSDSLAASNVIGSNIFNVLIVLGISSLITPLKVKSRIVRRDVPLLMAISCAVWA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
MSSTGLLTLQAGVFLIFCLILNTIWEINTMNEKGEETKDAEPEIEELKDNHKGKLNILLK
HCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHH
LILGIFLLSFGSNILVNGSQTLATLLGVNEIVIGLTIVATGTSLPELVTSIIAAFKGKTD
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCC
LAIGNVIGSNLLNQLLILGSCSIFSGFKGLVIEQSLIKVDLPFMVLTTFACLPIFWSKGK
HHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
ITRIEGFILLNLYIFYILDKILFLNEFNFLSELRIGLFIYFALLITFLILQEKLKFSNS
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDFLFPIIEIVLGIVLLFSGGEFFIQGAIFLSLILGIPQIVIGLTVVSLGTSSPELLVS
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LSSILKGSDSLAASNVIGSNIFNVLIVLGISSLITPLKVKSRIVRRDVPLLMAISCAVWA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
MSSTGLLTLQAGVFLIFCLILNTIWEINTMNEKGEETKDAEPEIEELKDNHKGKLNILLK
HCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHH
LILGIFLLSFGSNILVNGSQTLATLLGVNEIVIGLTIVATGTSLPELVTSIIAAFKGKTD
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCC
LAIGNVIGSNLLNQLLILGSCSIFSGFKGLVIEQSLIKVDLPFMVLTTFACLPIFWSKGK
HHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
ITRIEGFILLNLYIFYILDKILFLNEFNFLSELRIGLFIYFALLITFLILQEKLKFSNS
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]