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The map label for this gene is trpF [H]

Identifier: 123968128

GI number: 123968128

Start: 518183

End: 518839

Strand: Reverse

Name: trpF [H]

Synonym: A9601_05931

Alternate gene names: 123968128

Gene position: 518839-518183 (Counterclockwise)

Preceding gene: 123968130

Following gene: 123968121

Centisome position: 31.07

GC content: 30.44

Gene sequence:

>657_bases
ATGCCCAAGACTAATACTTTAATTAAAATTTGTGGGCTAACTTCAGAAGAACAAGCTCTTCAAGTCTCAAAATTAGGAGC
CCATGCTATCGGCATTATTTCAGTGGAAGAGTCGCCAAGATTTATATCAGCTGAGATTAAGAAAAAAATTTTTAAAACCT
TAGAAAGGTTTTATCCAAAAATTGAGAGAGTATCAGTTGTAAAGAATTGTCCAATAGACTTAATTATTAAAAATTTCTTA
GGAAGCCCTAGTGAAACTATCATTCAATTACATGGAGATGAAGATATTGATTACTGCAAAAAAATAAGGGATAAAATTCC
CAATATTGGCTTATGGAAGGCTTTCAGAATAAAAACAGAAAAGGATATTGATAAAATAAAACCTTTTGAGGATTTTGTAG
ATGCTATCCTACTTGATTCTTGGAATAAAGAAACTTATGGAGGTTCAGGGGAAAAAATAAAATCTTCTTATTTAAAGAAT
CTCCAATTTAGCAAACCTTGGTGGTTAGCAGGTGGAATATCAATTGAATGGATTAATGAAATACTTACAGATATCAAACC
TGATGGACTAGATATTTCAAGTAGTATTGAAATTTCTCCGGGTTTAAAAGATATTAAAAAAACAGAGGAACTTTTTAAGT
TGTTAAAAGGAATTTAG

Upstream 100 bases:

>100_bases
TTTAAAGGGAATTCCCCATATTTTAAAAATTTGCCAACTTCTCAAAAATAAACTCCGCTATATTTAGCAATAATATTAAT
TTTACATACATGATAATCAT

Downstream 100 bases:

>100_bases
TAATTATTAGTAGCGGACTGCTGTTTTACAAGCTCAAAAAATTCTTGTTTTAAGCTTAAATCGTGTCTAAAATCGCCTCT
CACAACAGAATTAATCATGC

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MPKTNTLIKICGLTSEEQALQVSKLGAHAIGIISVEESPRFISAEIKKKIFKTLERFYPKIERVSVVKNCPIDLIIKNFL
GSPSETIIQLHGDEDIDYCKKIRDKIPNIGLWKAFRIKTEKDIDKIKPFEDFVDAILLDSWNKETYGGSGEKIKSSYLKN
LQFSKPWWLAGGISIEWINEILTDIKPDGLDISSSIEISPGLKDIKKTEELFKLLKGI

Sequences:

>Translated_218_residues
MPKTNTLIKICGLTSEEQALQVSKLGAHAIGIISVEESPRFISAEIKKKIFKTLERFYPKIERVSVVKNCPIDLIIKNFL
GSPSETIIQLHGDEDIDYCKKIRDKIPNIGLWKAFRIKTEKDIDKIKPFEDFVDAILLDSWNKETYGGSGEKIKSSYLKN
LQFSKPWWLAGGISIEWINEILTDIKPDGLDISSSIEISPGLKDIKKTEELFKLLKGI
>Mature_217_residues
PKTNTLIKICGLTSEEQALQVSKLGAHAIGIISVEESPRFISAEIKKKIFKTLERFYPKIERVSVVKNCPIDLIIKNFLG
SPSETIIQLHGDEDIDYCKKIRDKIPNIGLWKAFRIKTEKDIDKIKPFEDFVDAILLDSWNKETYGGSGEKIKSSYLKNL
QFSKPWWLAGGISIEWINEILTDIKPDGLDISSSIEISPGLKDIKKTEELFKLLKGI

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=213, Percent_Identity=29.5774647887324, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 24723; Mature: 24592

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTNTLIKICGLTSEEQALQVSKLGAHAIGIISVEESPRFISAEIKKKIFKTLERFYPK
CCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCH
IERVSVVKNCPIDLIIKNFLGSPSETIIQLHGDEDIDYCKKIRDKIPNIGLWKAFRIKTE
HHHHHHHHHCCHHHHHHHHCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCCHHEEECCH
KDIDKIKPFEDFVDAILLDSWNKETYGGSGEKIKSSYLKNLQFSKPWWLAGGISIEWINE
HHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
ILTDIKPDGLDISSSIEISPGLKDIKKTEELFKLLKGI
HHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKTNTLIKICGLTSEEQALQVSKLGAHAIGIISVEESPRFISAEIKKKIFKTLERFYPK
CCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCH
IERVSVVKNCPIDLIIKNFLGSPSETIIQLHGDEDIDYCKKIRDKIPNIGLWKAFRIKTE
HHHHHHHHHCCHHHHHHHHCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCCHHEEECCH
KDIDKIKPFEDFVDAILLDSWNKETYGGSGEKIKSSYLKNLQFSKPWWLAGGISIEWINE
HHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
ILTDIKPDGLDISSSIEISPGLKDIKKTEELFKLLKGI
HHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA