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The map label for this gene is ubiA [H]

Identifier: 123968049

GI number: 123968049

Start: 446166

End: 447074

Strand: Reverse

Name: ubiA [H]

Synonym: A9601_05121

Alternate gene names: 123968049

Gene position: 447074-446166 (Counterclockwise)

Preceding gene: 123968051

Following gene: 123968048

Centisome position: 26.77

GC content: 31.57

Gene sequence:

>909_bases
ATGAAATATACAATAGGGTTTATGCAGAATAAAAATCGACAAATTAGATTAAATACTTTTTTTGAATTATTAAGGTGGAA
TAAGCCGACTGGAAGAATGATCTTACTTATACCAGCTGGGTGGAGTTTATATTTAACTCCTGGTGCTAATCCAACATTTT
TAATGTTGTTAAGAATAATCCTTGGAGGGCTATTAGTAAGTGGATTAGGCTGCGTAGTTAATGATATTTGGGATAAAAAA
ATTGATCAAAAAGTTATTAGGACAAAAAATAGACCTCTAGCTGCAAATAAAATCAGTCTTAAAACGGCTTATTCAATTCT
TTTCTTTTTAATTTTATGCAGTTTCTTTTTAACTTTGTCACTACCTCAACCTGGCAGGATCCTTTCGATTTCACTCGCTT
TTCTATCTTTGCCTATTATCTTAATTTATCCTTCTGCTAAAAGATGGTTTAAATATCCTCAATTAATCTTATCCATATGC
TGGGGTTTTGCTGTCTTAATACCCTGGGCCGCAAATGAAGGCAATTTGAATAGTATTGTTTTATTGTTTTGCTGGCTAGC
TACTATTTTTTGGACTTTTGGCTTCGACACGATTTATGCCTTAGCGGATAAAAAATATGATATCAAAATTGGAATAAATA
GTTCCGCTGTTAACCTCCAGAACTATACAAAAGTAACTATTCAAATTTGTTATTTTTTAACTTCTATTTTTCTCGCATTT
TGCGGATTTATTAATCAAATGGATTTTATTTTCTGGCCAATTTGGCTTACGACGGCAATCTTAATGCAGCGAGATATACT
AAAAGTATTTCCTGAGGAAAAGCAATCAATAAAAAATATTGGGAATCACTTCAAAAATCAATCAATTTATGGTGGAGTCC
TACTATTAGGAATTATTATTGCCACATAA

Upstream 100 bases:

>100_bases
TTTTATAAGATGCAGATATATTTAATCCATTAATAAATATACCCAAGATTGATTATTAAATAATAGAAATCATTTAATCC
TAGTAAGATTATTTAAAGTT

Downstream 100 bases:

>100_bases
ATTCTAAATATGGTTTCCAGATTACAAAAAGGTGATCTAATAGATATTTTAGCTCCAGGCTCTTTTATTGATGAAGAGGA
AAATTTTCAAAAAGGCATAG

Product: prenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKYTIGFMQNKNRQIRLNTFFELLRWNKPTGRMILLIPAGWSLYLTPGANPTFLMLLRIILGGLLVSGLGCVVNDIWDKK
IDQKVIRTKNRPLAANKISLKTAYSILFFLILCSFFLTLSLPQPGRILSISLAFLSLPIILIYPSAKRWFKYPQLILSIC
WGFAVLIPWAANEGNLNSIVLLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNYTKVTIQICYFLTSIFLAF
CGFINQMDFIFWPIWLTTAILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIIIAT

Sequences:

>Translated_302_residues
MKYTIGFMQNKNRQIRLNTFFELLRWNKPTGRMILLIPAGWSLYLTPGANPTFLMLLRIILGGLLVSGLGCVVNDIWDKK
IDQKVIRTKNRPLAANKISLKTAYSILFFLILCSFFLTLSLPQPGRILSISLAFLSLPIILIYPSAKRWFKYPQLILSIC
WGFAVLIPWAANEGNLNSIVLLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNYTKVTIQICYFLTSIFLAF
CGFINQMDFIFWPIWLTTAILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIIIAT
>Mature_302_residues
MKYTIGFMQNKNRQIRLNTFFELLRWNKPTGRMILLIPAGWSLYLTPGANPTFLMLLRIILGGLLVSGLGCVVNDIWDKK
IDQKVIRTKNRPLAANKISLKTAYSILFFLILCSFFLTLSLPQPGRILSISLAFLSLPIILIYPSAKRWFKYPQLILSIC
WGFAVLIPWAANEGNLNSIVLLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNYTKVTIQICYFLTSIFLAF
CGFINQMDFIFWPIWLTTAILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIIIAT

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=210, Percent_Identity=35.7142857142857, Blast_Score=128, Evalue=6e-30,
Organism=Escherichia coli, GI1790473, Length=298, Percent_Identity=32.2147651006711, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17553718, Length=288, Percent_Identity=32.2916666666667, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI32565247, Length=289, Percent_Identity=32.8719723183391, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17553720, Length=345, Percent_Identity=28.1159420289855, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI32565245, Length=143, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32565243, Length=143, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324370, Length=228, Percent_Identity=34.2105263157895, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21355567, Length=285, Percent_Identity=29.8245614035088, Blast_Score=128, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34532; Mature: 34532

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTIGFMQNKNRQIRLNTFFELLRWNKPTGRMILLIPAGWSLYLTPGANPTFLMLLRII
CCEEEEEEECCCCEEEHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHH
LGGLLVSGLGCVVNDIWDKKIDQKVIRTKNRPLAANKISLKTAYSILFFLILCSFFLTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
LPQPGRILSISLAFLSLPIILIYPSAKRWFKYPQLILSICWGFAVLIPWAANEGNLNSIV
CCCCCCEEEEHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNYTKVTIQICYFLTSIFLAF
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHH
CGFINQMDFIFWPIWLTTAILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIII
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AT
CC
>Mature Secondary Structure
MKYTIGFMQNKNRQIRLNTFFELLRWNKPTGRMILLIPAGWSLYLTPGANPTFLMLLRII
CCEEEEEEECCCCEEEHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHH
LGGLLVSGLGCVVNDIWDKKIDQKVIRTKNRPLAANKISLKTAYSILFFLILCSFFLTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
LPQPGRILSISLAFLSLPIILIYPSAKRWFKYPQLILSICWGFAVLIPWAANEGNLNSIV
CCCCCCEEEEHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNYTKVTIQICYFLTSIFLAF
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHH
CGFINQMDFIFWPIWLTTAILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIII
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AT
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA