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The map label for this gene is 121639735

Identifier: 121639735

GI number: 121639735

Start: 4254852

End: 4256402

Strand: Direct

Name: 121639735

Synonym: BCG_3880

Alternate gene names: NA

Gene position: 4254852-4256402 (Clockwise)

Preceding gene: 121639734

Following gene: 121639736

Centisome position: 97.26

GC content: 61.83

Gene sequence:

>1551_bases
GTGCAGGTCACAAGCGTTGGTCACGCCGGCTTTCTGATCCAGACCCAGGCCGGCAGCATCCTGTGCGACCCTTGGGTCAA
TCCGGCCTACTTTGCGTCTTGGTTTCCGTTCCCCGACAACAGCGGGCTGGACTGGGGCGCTTTGGGTGAGTGCGATTATC
TGTATGTCTCGCACCTACATAAGGACCACTTCGACGCGGAAAATCTACGAGCGCACGTCAACAAGGACGCCGTCGTGCTG
CTGCCCGACTTTCCGGTACCCGACCTGCGAAATGAGTTGCAGAAGTTAGGATTTCATCGGTTCTTCGAAACCACCGACTC
GGTCAAACACCGCCTGAGGGGACCCAACGGCGATCTCGACGTGATGATCATCGCACTGCGGGCCCCCGCCGACGGTCCGA
TCGGCGACTCGGCGCTAGTCGTTGCCGACGGCGAAACAACGGCTTTCAACATGAACGACGCCCGCCCGGTCGATTTGGAC
GTGCTGGCATCGGAGTTCGGTCACATCGACGTGCATATGCTGCAGTACTCGGGCGCGATCTGGTACCCGATGGTCTACGA
CATGCCGGCGCGCGCGAAGGATGCGTTCGGCGCCCAAAAGCGGCAACGGCAGATGGACCGTGCTCGCCAGTACATCGCGC
AGGTGGGAGCGACGTGGGTGGTGCCGTCGGCGGGGCCGCCATGCTTTTTAGCCCCCGAGCTGCGCCACCTCAACGACGAC
GGTAGCGATCCGGCCAATATCTTCCCCGACCAGATGGTGTTCCTGGATCAGATGCGGGCGCACGGCCAGGACGGCGGGCT
GCTGATGATCCCCGGCTCGACTGCGGATTTCACTGGTACAACCCTGAATTCATTGCGCCATCCACTGCCCGCCGAACAGG
TCGAGGCCATCTTTACCACCGACAAAGCCGCATACATCGCTGACTATGCCGACCGGATGGCGCCGGTGCTCGCCGCGCAA
AAGGCTGGCTGGGCCGCCGCCGCCGGCGAGCCACTGCTGCAGCCGCTGCGCACCCTGTTCGAGCCGATCATGCTGCAAAG
CAACGAGATCTGCGACGGCATCGGATACCCGGTCGAGCTCGCCATCGGTCCCGAAACCATTGTTTTGGACTTTCCGAAAA
GAGCTGTACGAGAACCGATTCCCGACGAGAGGTTCCGCTACGGGTTCGCGATCGCGCCGGAGCTGGTGCGCACGGTGCTG
CGCGACAACGAACCCGACTGGGTCAACACCATCTTCTTATCCACCCGATTTCGGGCATGGCGGGTTGGTGGCTACAACGA
ATACCTTTACACGTTCTTCAAGTGTCTGACCGACGAACGCATCGCCTACGCCGACGGCTGGTTCGCCGAGGCCCACGATG
ACTCCTCATCGATCACCCTGAACGGTTGGGAGATCCAGCGCCGCTGCCCCCATCTCAAAGCCGACCTATCGAAATTCGGT
GTGGTGGAAGGCAACACGCTCACTTGTAACCTGCACGGCTGGCAGTGGCGTCTGGACGACGGTCGCTGCCTCACCGCCCG
GGGCCATCAACTACGCAGTTCACGGCCATGA

Upstream 100 bases:

>100_bases
CGCATCGACTACTACCGCCGGCTGTGGCAGGCCGAAGACGACAGCTCACGCTAAGCTCGAGGCTGCGCTTTGCGCTCGTA
AGCTCTTCCGAAAGGTAGCT

Downstream 100 bases:

>100_bases
TGCAGTTCTACGACGACGGCGTTGTACAGCTGGATCGTGCTGCACTCACGCTGCGCCGCTATCATTTTCCTTCGGGCACG
GCCAAGGTCATCCCACTGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MQVTSVGHAGFLIQTQAGSILCDPWVNPAYFASWFPFPDNSGLDWGALGECDYLYVSHLHKDHFDAENLRAHVNKDAVVL
LPDFPVPDLRNELQKLGFHRFFETTDSVKHRLRGPNGDLDVMIIALRAPADGPIGDSALVVADGETTAFNMNDARPVDLD
VLASEFGHIDVHMLQYSGAIWYPMVYDMPARAKDAFGAQKRQRQMDRARQYIAQVGATWVVPSAGPPCFLAPELRHLNDD
GSDPANIFPDQMVFLDQMRAHGQDGGLLMIPGSTADFTGTTLNSLRHPLPAEQVEAIFTTDKAAYIADYADRMAPVLAAQ
KAGWAAAAGEPLLQPLRTLFEPIMLQSNEICDGIGYPVELAIGPETIVLDFPKRAVREPIPDERFRYGFAIAPELVRTVL
RDNEPDWVNTIFLSTRFRAWRVGGYNEYLYTFFKCLTDERIAYADGWFAEAHDDSSSITLNGWEIQRRCPHLKADLSKFG
VVEGNTLTCNLHGWQWRLDDGRCLTARGHQLRSSRP

Sequences:

>Translated_516_residues
MQVTSVGHAGFLIQTQAGSILCDPWVNPAYFASWFPFPDNSGLDWGALGECDYLYVSHLHKDHFDAENLRAHVNKDAVVL
LPDFPVPDLRNELQKLGFHRFFETTDSVKHRLRGPNGDLDVMIIALRAPADGPIGDSALVVADGETTAFNMNDARPVDLD
VLASEFGHIDVHMLQYSGAIWYPMVYDMPARAKDAFGAQKRQRQMDRARQYIAQVGATWVVPSAGPPCFLAPELRHLNDD
GSDPANIFPDQMVFLDQMRAHGQDGGLLMIPGSTADFTGTTLNSLRHPLPAEQVEAIFTTDKAAYIADYADRMAPVLAAQ
KAGWAAAAGEPLLQPLRTLFEPIMLQSNEICDGIGYPVELAIGPETIVLDFPKRAVREPIPDERFRYGFAIAPELVRTVL
RDNEPDWVNTIFLSTRFRAWRVGGYNEYLYTFFKCLTDERIAYADGWFAEAHDDSSSITLNGWEIQRRCPHLKADLSKFG
VVEGNTLTCNLHGWQWRLDDGRCLTARGHQLRSSRP
>Mature_516_residues
MQVTSVGHAGFLIQTQAGSILCDPWVNPAYFASWFPFPDNSGLDWGALGECDYLYVSHLHKDHFDAENLRAHVNKDAVVL
LPDFPVPDLRNELQKLGFHRFFETTDSVKHRLRGPNGDLDVMIIALRAPADGPIGDSALVVADGETTAFNMNDARPVDLD
VLASEFGHIDVHMLQYSGAIWYPMVYDMPARAKDAFGAQKRQRQMDRARQYIAQVGATWVVPSAGPPCFLAPELRHLNDD
GSDPANIFPDQMVFLDQMRAHGQDGGLLMIPGSTADFTGTTLNSLRHPLPAEQVEAIFTTDKAAYIADYADRMAPVLAAQ
KAGWAAAAGEPLLQPLRTLFEPIMLQSNEICDGIGYPVELAIGPETIVLDFPKRAVREPIPDERFRYGFAIAPELVRTVL
RDNEPDWVNTIFLSTRFRAWRVGGYNEYLYTFFKCLTDERIAYADGWFAEAHDDSSSITLNGWEIQRRCPHLKADLSKFG
VVEGNTLTCNLHGWQWRLDDGRCLTARGHQLRSSRP

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3818_MYCTU (O07805)

Other databases:

- EMBL:   AE000516
- EMBL:   BX842584
- PIR:   F70521
- RefSeq:   NP_218335.1
- RefSeq:   NP_338479.1
- ProteinModelPortal:   O07805
- SMR:   O07805
- EnsemblBacteria:   EBMYCT00000002853
- EnsemblBacteria:   EBMYCT00000069923
- GeneID:   886153
- GeneID:   922585
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3926
- KEGG:   mtu:Rv3818
- TIGR:   MT3926
- TubercuList:   Rv3818
- GeneTree:   EBGT00050000017624
- HOGENOM:   HBG564773
- OMA:   HLLQYSG
- ProtClustDB:   CLSK872255
- InterPro:   IPR017941
- Gene3D:   G3DSA:2.102.10.10

Pfam domain/function: PF00355 Rieske; SSF50022 Rieske_dom

EC number: NA

Molecular weight: Translated: 57648; Mature: 57648

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS51296 RIESKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVTSVGHAGFLIQTQAGSILCDPWVNPAYFASWFPFPDNSGLDWGALGECDYLYVSHLH
CCCCCCCCCCEEEEECCCCEEECCCCCHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHH
KDHFDAENLRAHVNKDAVVLLPDFPVPDLRNELQKLGFHRFFETTDSVKHRLRGPNGDLD
HHCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VMIIALRAPADGPIGDSALVVADGETTAFNMNDARPVDLDVLASEFGHIDVHMLQYSGAI
EEEEEEECCCCCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCEE
WYPMVYDMPARAKDAFGAQKRQRQMDRARQYIAQVGATWVVPSAGPPCFLAPELRHLNDD
EECEEECCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEECHHHHHCCCC
GSDPANIFPDQMVFLDQMRAHGQDGGLLMIPGSTADFTGTTLNSLRHPLPAEQVEAIFTT
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHCC
DKAAYIADYADRMAPVLAAQKAGWAAAAGEPLLQPLRTLFEPIMLQSNEICDGIGYPVEL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
AIGPETIVLDFPKRAVREPIPDERFRYGFAIAPELVRTVLRDNEPDWVNTIFLSTRFRAW
EECCCEEEEECCHHHHHCCCCCHHHHCCEEHHHHHHHHHHCCCCCCCEEEEEEEECCEEE
RVGGYNEYLYTFFKCLTDERIAYADGWFAEAHDDSSSITLNGWEIQRRCPHLKADLSKFG
EECCCHHHHHHHHHHHCCCCEEECCCCEEECCCCCCEEEEECHHHHHHCCCHHHHHHHCC
VVEGNTLTCNLHGWQWRLDDGRCLTARGHQLRSSRP
EEECCEEEEEECCEEEEECCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MQVTSVGHAGFLIQTQAGSILCDPWVNPAYFASWFPFPDNSGLDWGALGECDYLYVSHLH
CCCCCCCCCCEEEEECCCCEEECCCCCHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHH
KDHFDAENLRAHVNKDAVVLLPDFPVPDLRNELQKLGFHRFFETTDSVKHRLRGPNGDLD
HHCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VMIIALRAPADGPIGDSALVVADGETTAFNMNDARPVDLDVLASEFGHIDVHMLQYSGAI
EEEEEEECCCCCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCEE
WYPMVYDMPARAKDAFGAQKRQRQMDRARQYIAQVGATWVVPSAGPPCFLAPELRHLNDD
EECEEECCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEECHHHHHCCCC
GSDPANIFPDQMVFLDQMRAHGQDGGLLMIPGSTADFTGTTLNSLRHPLPAEQVEAIFTT
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHCC
DKAAYIADYADRMAPVLAAQKAGWAAAAGEPLLQPLRTLFEPIMLQSNEICDGIGYPVEL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
AIGPETIVLDFPKRAVREPIPDERFRYGFAIAPELVRTVLRDNEPDWVNTIFLSTRFRAW
EECCCEEEEECCHHHHHCCCCCHHHHCCEEHHHHHHHHHHCCCCCCCEEEEEEEECCEEE
RVGGYNEYLYTFFKCLTDERIAYADGWFAEAHDDSSSITLNGWEIQRRCPHLKADLSKFG
EECCCHHHHHHHHHHHCCCCEEECCCCEEECCCCCCEEEEECHHHHHHCCCHHHHHHHCC
VVEGNTLTCNLHGWQWRLDDGRCLTARGHQLRSSRP
EEECCEEEEEECCEEEEECCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036