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The map label for this gene is PE_PGRS62 [H]

Identifier: 121639729

GI number: 121639729

Start: 4248974

End: 4250488

Strand: Direct

Name: PE_PGRS62 [H]

Synonym: BCG_3874

Alternate gene names: 121639729

Gene position: 4248974-4250488 (Clockwise)

Preceding gene: 121639728

Following gene: 121639734

Centisome position: 97.13

GC content: 64.09

Gene sequence:

>1515_bases
GTGTCGTTCGTGGTCACAGTGCCGGAGGCCGTGGCGGCTGCGGCGGGGGATTTGGCGGCCATCGGCTCGACGCTTCGGGA
AGCGACCGCTGCGGCGGCGGGCCCCACGACCGGGCTGGCGGCCGCGGCCGCCGACGACGTGTCGATCGCTGTCTCGCAGC
TGTTCGGCAGGTACGGCCAGGAATTTCAAACCGTGAGCAACCAACTGGCCGCGTTTCATACCGAGTTCGTACGCACGTTG
AACCGCGGCGCGGCGGCGTATCTCAACACCGAAAGCGCTAACGGCGGGCAGCTGTTCGGTCAGATCGAGGCGGGACAGCG
CGCCGTTTCCGCGGCCGCGGCCGCCGCTCCGGGCGGCGCATACGGCCAACTCGTTGCCAACACGGCCACCAACCTGGAAT
CCCTCTACGGCGCATGGTCGGCCAACCCGTTCCCATTCCTCCGCCAGATCATCGCCAACCAGCAGGTTTACTGGCAGCAG
ATCGCCGCGGCGCTCGCCAACGCCGTCCAGAACTTCCCCGCCCTGGTGGCGAATTTGCCAGCGGCCATCGACGCGGCCGT
CCAGCAATTCCTGGCCTTCAACGCGGCGTACTACATCCAACAGATTATTAGCTCGCAGATCGGCTTCGCCCAGCTATTCG
CCACGACGGTCGGTCAGGGGGTCACCAGCGTCATTGCCGGGTGGCCCAACCTTGCGGCGGAGCTTCAGCTAGCGTTTCAA
CAGCTTCTGGTGGGTGACTACAACGCCGCGGTGGCGAACCTGGGTAAGGCCATGACAAACCTTCTGGTCACCGGGTTCGA
CACCAGCGACGTGACGATCGGCACAATGGGCACCACCATTAGTGTCACCGCGAAACCCAAGCTGCTGGGCCCGCTGGGAG
ATCTGTTCACCATCATGACCATCCCGGCACAAGAGGCGCAGTACTTCACCAACCTGATGCCCCCCTCCATCCTGCGAGAC
ATGTCGCAGAACTTCACCAACGTGCTCACGACGCTCTCCAACCCGAACATCCAGGCGGTCGCTTCGTTCGATATCGCAAC
CACCGCCGGGACTTTGAGCACCTTCTTCGGGGTGCCATTGGTGCTCACTTACGCCACATTGGGTGCGCCGTTCGCGTCAC
TGAACGCGATTGCGACGAGCGCGGAAACCATCGAGCAGGCCCTGTTGGCCGGCAACTACCTAGGGGCGGTGGGTGCGCTT
ATCGACGCCCCGGCCCACGCGTTAGACGGCTTCCTCAACAGCGCAACCGTGTTGGATACGCCGATCCTGGTGCCCACGGG
GCTCCCGTCCCCTCTGCCCCCGACGGTCGGGATCACGCTGCACTTGCCTTTCGACGGGATTCTCGTGCCGCCGCATCCCG
TCACCGCGACGATCAGCTTCCCGGGTGCTCCGGTTCCTATTCCCGGTTTCCCAACCACCGTAACCGTTTTCGGCACACCC
TTCATGGGAATGGCTCCGCTGCTGATCAACTACATTCCCCAACAGCTCGCCCTGGCAATCAAACCGGCGGCTTAG

Upstream 100 bases:

>100_bases
TTTGCGGCGCGGAATCGCCGGCGCATAGACACCCTGTGCCATTAGGCTCCATTTGCCGGGCTGATCACCGGGTCGCCGCA
GGCCAGTCGAGAGGAACAAC

Downstream 100 bases:

>100_bases
CGCGGCGTGGCCCGTTGGTTAGTGTCGTAGGTTGCCATGCCAAGCTCCAACCATGCGGTTAGCAGCCGCTGATCTGCCGC
CGCGGCCACAACCTCGTCGT

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MSFVVTVPEAVAAAAGDLAAIGSTLREATAAAAGPTTGLAAAAADDVSIAVSQLFGRYGQEFQTVSNQLAAFHTEFVRTL
NRGAAAYLNTESANGGQLFGQIEAGQRAVSAAAAAAPGGAYGQLVANTATNLESLYGAWSANPFPFLRQIIANQQVYWQQ
IAAALANAVQNFPALVANLPAAIDAAVQQFLAFNAAYYIQQIISSQIGFAQLFATTVGQGVTSVIAGWPNLAAELQLAFQ
QLLVGDYNAAVANLGKAMTNLLVTGFDTSDVTIGTMGTTISVTAKPKLLGPLGDLFTIMTIPAQEAQYFTNLMPPSILRD
MSQNFTNVLTTLSNPNIQAVASFDIATTAGTLSTFFGVPLVLTYATLGAPFASLNAIATSAETIEQALLAGNYLGAVGAL
IDAPAHALDGFLNSATVLDTPILVPTGLPSPLPPTVGITLHLPFDGILVPPHPVTATISFPGAPVPIPGFPTTVTVFGTP
FMGMAPLLINYIPQQLALAIKPAA

Sequences:

>Translated_504_residues
MSFVVTVPEAVAAAAGDLAAIGSTLREATAAAAGPTTGLAAAAADDVSIAVSQLFGRYGQEFQTVSNQLAAFHTEFVRTL
NRGAAAYLNTESANGGQLFGQIEAGQRAVSAAAAAAPGGAYGQLVANTATNLESLYGAWSANPFPFLRQIIANQQVYWQQ
IAAALANAVQNFPALVANLPAAIDAAVQQFLAFNAAYYIQQIISSQIGFAQLFATTVGQGVTSVIAGWPNLAAELQLAFQ
QLLVGDYNAAVANLGKAMTNLLVTGFDTSDVTIGTMGTTISVTAKPKLLGPLGDLFTIMTIPAQEAQYFTNLMPPSILRD
MSQNFTNVLTTLSNPNIQAVASFDIATTAGTLSTFFGVPLVLTYATLGAPFASLNAIATSAETIEQALLAGNYLGAVGAL
IDAPAHALDGFLNSATVLDTPILVPTGLPSPLPPTVGITLHLPFDGILVPPHPVTATISFPGAPVPIPGFPTTVTVFGTP
FMGMAPLLINYIPQQLALAIKPAA
>Mature_503_residues
SFVVTVPEAVAAAAGDLAAIGSTLREATAAAAGPTTGLAAAAADDVSIAVSQLFGRYGQEFQTVSNQLAAFHTEFVRTLN
RGAAAYLNTESANGGQLFGQIEAGQRAVSAAAAAAPGGAYGQLVANTATNLESLYGAWSANPFPFLRQIIANQQVYWQQI
AAALANAVQNFPALVANLPAAIDAAVQQFLAFNAAYYIQQIISSQIGFAQLFATTVGQGVTSVIAGWPNLAAELQLAFQQ
LLVGDYNAAVANLGKAMTNLLVTGFDTSDVTIGTMGTTISVTAKPKLLGPLGDLFTIMTIPAQEAQYFTNLMPPSILRDM
SQNFTNVLTTLSNPNIQAVASFDIATTAGTLSTFFGVPLVLTYATLGAPFASLNAIATSAETIEQALLAGNYLGAVGALI
DAPAHALDGFLNSATVLDTPILVPTGLPSPLPPTVGITLHLPFDGILVPPHPVTATISFPGAPVPIPGFPTTVTVFGTPF
MGMAPLLINYIPQQLALAIKPAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 51822; Mature: 51691

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVVTVPEAVAAAAGDLAAIGSTLREATAAAAGPTTGLAAAAADDVSIAVSQLFGRYGQ
CCEEEECHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHH
EFQTVSNQLAAFHTEFVRTLNRGAAAYLNTESANGGQLFGQIEAGQRAVSAAAAAAPGGA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHHCCCCCC
YGQLVANTATNLESLYGAWSANPFPFLRQIIANQQVYWQQIAAALANAVQNFPALVANLP
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
AAIDAAVQQFLAFNAAYYIQQIISSQIGFAQLFATTVGQGVTSVIAGWPNLAAELQLAFQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QLLVGDYNAAVANLGKAMTNLLVTGFDTSDVTIGTMGTTISVTAKPKLLGPLGDLFTIMT
HHHHCCHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCEEEEEECCHHHCCHHHHHHHHC
IPAQEAQYFTNLMPPSILRDMSQNFTNVLTTLSNPNIQAVASFDIATTAGTLSTFFGVPL
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHH
VLTYATLGAPFASLNAIATSAETIEQALLAGNYLGAVGALIDAPAHALDGFLNSATVLDT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCHHCCC
PILVPTGLPSPLPPTVGITLHLPFDGILVPPHPVTATISFPGAPVPIPGFPTTVTVFGTP
CEEEECCCCCCCCCCCEEEEEECCCCEEECCCCCEEEEECCCCCCCCCCCCCEEEEECCC
FMGMAPLLINYIPQQLALAIKPAA
CHHHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure 
SFVVTVPEAVAAAAGDLAAIGSTLREATAAAAGPTTGLAAAAADDVSIAVSQLFGRYGQ
CEEEECHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHH
EFQTVSNQLAAFHTEFVRTLNRGAAAYLNTESANGGQLFGQIEAGQRAVSAAAAAAPGGA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHHCCCCCC
YGQLVANTATNLESLYGAWSANPFPFLRQIIANQQVYWQQIAAALANAVQNFPALVANLP
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
AAIDAAVQQFLAFNAAYYIQQIISSQIGFAQLFATTVGQGVTSVIAGWPNLAAELQLAFQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QLLVGDYNAAVANLGKAMTNLLVTGFDTSDVTIGTMGTTISVTAKPKLLGPLGDLFTIMT
HHHHCCHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCEEEEEECCHHHCCHHHHHHHHC
IPAQEAQYFTNLMPPSILRDMSQNFTNVLTTLSNPNIQAVASFDIATTAGTLSTFFGVPL
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHH
VLTYATLGAPFASLNAIATSAETIEQALLAGNYLGAVGALIDAPAHALDGFLNSATVLDT
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHCCCHHCCC
PILVPTGLPSPLPPTVGITLHLPFDGILVPPHPVTATISFPGAPVPIPGFPTTVTVFGTP
CEEEECCCCCCCCCCCEEEEEECCCCEEECCCCCEEEEECCCCCCCCCCCCCEEEEECCC
FMGMAPLLINYIPQQLALAIKPAA
CHHHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]