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The map label for this gene is kstR

Identifier: 121639494

GI number: 121639494

Start: 3995376

End: 3995975

Strand: Direct

Name: kstR

Synonym: BCG_3639

Alternate gene names: 121639494

Gene position: 3995376-3995975 (Clockwise)

Preceding gene: 121639492

Following gene: 121639496

Centisome position: 91.33

GC content: 65.67

Gene sequence:

>600_bases
GTGGCGGTACTTGCCGAGTCCGAGCTCGGATCGGAGGCACAGCGGGAGCGCCGCAAGCGCATCTTGGACGCCACCATGGC
TATCGCGTCCAAAGGCGGCTATGAGGCGGTGCAGATGCGCGCCGTCGCCGACCGCGCCGACGTCGCGGTTGGCACGCTGT
ACCGGTACTTCCCGTCGAAGGTGCATCTGCTGGTGTCGGCGCTGGGTCGGGAATTCAGCCGCATCGACGCGAAAACCGAC
CGCTCCGCGGTCGCCGGGGCCACCCCCTTCCAGCGGCTGAACTTTATGGTCGGCAAGCTCAACCGCGCGATGCAACGCAA
TCCGCTACTCACCGAGGCCATGACACGTGCCTACGTGTTCGCCGACGCCTCGGCGGCCAGCGAGGTCGACCAGGTCGAAA
AGCTCATCGACAGTATGTTCGCGCGTGCAATGGCCAACGGCGAACCAACCGAGGACCAGTACCACATAGCGCGGGTGATC
TCGGACGTGTGGTTGTCGAACCTGCTCGCGTGGCTTACCCGACGAGCCTCGGCTACCGACGTCAGCAAGCGGCTGGACCT
GGCCGTGCGGCTGCTGATCGGCGATCAAGACAGCGCCTAG

Upstream 100 bases:

>100_bases
TGCAAACGAACCGCCCGGAAGAGGAGCTGCCCGCTACATGTCGTCAGCGAACACGAACACCAGTAGCGCTCCCGACGCAC
CACCTCGCGCGGTCATGAAA

Downstream 100 bases:

>100_bases
AAGACTTACGCCGGCGGACCCGCGGTGCGGCCCCGGACCAGCTCGGTATCGAGCACCTCGATGACGGGCAGTCCGGACCG
CGGCGGCTTCAGCAATAGCT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTD
RSAVAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHIARVI
SDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQDSA

Sequences:

>Translated_199_residues
MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTD
RSAVAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHIARVI
SDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQDSA
>Mature_198_residues
AVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDR
SAVAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHIARVIS
DVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQDSA

Specific function: Controls the expression of genes used for utilizing diverse lipids as energy sources

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KSTR_MYCTU (P96856)

Other databases:

- EMBL:   BX842583
- PIR:   D70606
- RefSeq:   NP_218091.1
- ProteinModelPortal:   P96856
- SMR:   P96856
- EnsemblBacteria:   EBMYCT00000003145
- GeneID:   887204
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv3574
- TubercuList:   Rv3574
- GeneTree:   EBGT00050000014726
- HOGENOM:   HBG567280
- OMA:   NSHAECV
- ProtClustDB:   CLSK792573
- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647
- Gene3D:   G3DSA:1.10.357.10
- PRINTS:   PR00455

Pfam domain/function: PF00440 TetR_N; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 21967; Mature: 21836

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVF
HHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHIARVISDVWLSNLLAWLTRRASATD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VSKRLDLAVRLLIGDQDSA
HHHHHHHHHHHEECCCCCC
>Mature Secondary Structure 
AVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVF
HHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHIARVISDVWLSNLLAWLTRRASATD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VSKRLDLAVRLLIGDQDSA
HHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230