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The map label for this gene is 121639370

Identifier: 121639370

GI number: 121639370

Start: 3851324

End: 3852691

Strand: Direct

Name: 121639370

Synonym: BCG_3515

Alternate gene names: NA

Gene position: 3851324-3852691 (Clockwise)

Preceding gene: 121639369

Following gene: 121639372

Centisome position: 88.04

GC content: 69.08

Gene sequence:

>1368_bases
ATGACCACGTCCCGTACCCTGCGCCTGCTGGTGGTATCAGCGCTCGCGACGCTGTCTGGGTTGGGAACGCCGGTTGCCCA
CGCGGTTTCGCCGCCGCCGATCGACGAAAGATGGCTACCCGAATCTGCGCTGCCGGCGCCGCCGCGGCCGACCGTACAAC
GTGAGGTATGCACCGAGGTCACCGCCGAATCGGGACGGGCTTTCGGCCGGGCTGAGCGGTCCGCTCAACTCGCCGACCTC
GACCAGGTCTGGCGACTCACCCGCGGCGCCGGCCAACGGGTCGCGGTCATCGACACCGGCGTTGCGCGCCATCGACGGTT
GCCCAAGGTGGTTGCCGGCGGTGACTATGTCTTCACCGGGGACGGCACCGCGGATTGCGATGCACACGGCACGCTGGTGG
CCGGAATTATCGCGGCCGCACCGGATGCGCAAAGCGACAATTTCAGCGGGGTGGCACCCGATGTCACCTTGATTAGCATT
CGCCAGTCCAGCAGCAAGTTCGCACCGGTCGGCGACCCGTCCAGCACAGGTGTTGGTGACGTCGACACCATGGCGAAGGC
CGTGCGGACGGCCGCCGACCTCGGCGCGTCGGTGATCAACATCTCGTCGATTGCCTGCGTTCCGGCCGCGGCTGCGCCGG
ACGACCGCGCGCTAGGTGCCGCTTTGGCCTATGCGGTCGATGTCAAGAACGCCGTCATCGTGGCCGCGGCCGGCAATACC
GGCGGCGCCGCGCAGTGTCCGCCGCAGGCCCCCGGGGTAACCCGGGACAGCGTCACGGTTGCGGTGAGTCCGGCCTGGTA
CGACGACTACGTGCTGACCGTAGGTTCGGTGAACGCCCAAGGCGAACCCTCGGCATTCACTCTCGCCGGCCCCTGGGTGG
ATGTCGCCGCCACCGGCGAGGCGGTGACCTCGCTCAGCCCGTTCGGTGACGGGACCGTGAACAGGCTTGGCGGACAGCAT
GGTTCGATTCCGATATCCGGAACCAGTTATGCGGCGCCGGTCGTCAGCGGCCTGGCCGCCCTGATCCGGGCCCGCTTTCC
GACGTTGACCGCACGGCAGGTGATGCAGCGCATCGAATCTACCGCGCATCACCCACCCGCCGGATGGGATCCGCTCGTCG
GCAACGGCACGGTCGATGCCCTGGCTGCGGTCAGCAGCGACTCGATTCCGCAGGCCGGCACCGCAACGAGCGACCCCGCT
CCGGTGGCGGTGCCGGTCCCTAGGCGGTCAACGCCCGGCCCATCGGATCGCCGCGCCCTACACACCGCCTTTGCTGGTGC
CGCGATCTGCCTGCTCGCGCTGATGGCAACCCTGGCCACCGCCAGCCGCCGGCTACGGCCCGGGCGCAACGGTATCGCGG
GCGACTGA

Upstream 100 bases:

>100_bases
TCGAATTGCTGGAGTGTCTGGCGCTGATCGCAATGGTTCCATTGACCGCTTGGCTATGCGGCGCCTACAGCGCCGTTCGC
CACCTCGACCTGACATGGAC

Downstream 100 bases:

>100_bases
CGCGTTGGCTCTACTCAGCTCCGGTCCGGACGGCAGTGTCGCCAACACCGGCCACGGCGCCGGGATGGCAGCCGTCGGCA
GACCGAGGTCGTGTGCCACG

Product: putative secreted serine protease

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADL
DQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISI
RQSSSKFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT
GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQH
GSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPA
PVAVPVPRRSTPGPSDRRALHTAFAGAAICLLALMATLATASRRLRPGRNGIAGD

Sequences:

>Translated_455_residues
MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADL
DQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISI
RQSSSKFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT
GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQH
GSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPA
PVAVPVPRRSTPGPSDRRALHTAFAGAAICLLALMATLATASRRLRPGRNGIAGD
>Mature_454_residues
TTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADLD
QVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIR
QSSSKFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTG
GAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQHG
SIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAP
VAVPVPRRSTPGPSDRRALHTAFAGAAICLLALMATLATASRRLRPGRNGIAGD

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 46016; Mature: 45885

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCEEEECCCEEEEC
DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT
HHHHHHHHHHHHHHCHHHEEHHHHEEECCCCCCCCHHHHHHHHHHEECCCEEEEEECCCC
GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE
CCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECCCEEEECCCH
AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES
HHHCCCCCCCCHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL
HCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHH
HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV
CCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCEEEECCCEEEEC
DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT
HHHHHHHHHHHHHHCHHHEEHHHHEEECCCCCCCCHHHHHHHHHHEECCCEEEEEECCCC
GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE
CCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECCCEEEECCCH
AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES
HHHCCCCCCCCHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL
HCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHH
HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]