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The map label for this gene is yoeB

Identifier: 121639285

GI number: 121639285

Start: 3758600

End: 3758857

Strand: Direct

Name: yoeB

Synonym: BCG_3430

Alternate gene names: 121639285

Gene position: 3758600-3758857 (Clockwise)

Preceding gene: 121639284

Following gene: 121639286

Centisome position: 85.92

GC content: 59.69

Gene sequence:

>258_bases
GTGAGAAGCGTCAACTTCGATCCCGATGCCTGGGAGGACTTCTTGTTCTGGCTGGCCGCTGATCGCAAAACGGCCCGTCG
GATCACCCGGTTGATCGGAGAAATTCAGCGTGATCCGTTCAGCGGGATCGGCAAACCCGAGCCGCTCCAAGGTGAGTTGT
CGGGATACTGGTCGCGCCGGATCGACGACGAACACCGGCTAGTGTATCGAGCGGGCGACGACGAAGTCACGATGCTGAAG
GCCCGATACCACTACTGA

Upstream 100 bases:

>100_bases
ACGCCAGGCGGTTGATGGAAGCGGTTGCCCGGGATAAGGCTGGGCACTCGGCTTTCACCAAGTCTGTAGATGAGCTGCGG
GAGATGGCCGGCGGCGAGGA

Downstream 100 bases:

>100_bases
TTTGGGGGCTGGTGGTATTCCGGCGGGCTTAAGCTCCCCATGTGGCTCCCGGCAGCTGCGAAGCCCCGGACGTGTTCAAC
CCGGCCAAACTCGGTCCGCT

Product: hypothetical protein

Products: NA

Alternate protein names: Endoribonuclease YoeB; Putative mRNA interferase YoeB

Number of amino acids: Translated: 85; Mature: 85

Protein sequence:

>85_residues
MRSVNFDPDAWEDFLFWLAADRKTARRITRLIGEIQRDPFSGIGKPEPLQGELSGYWSRRIDDEHRLVYRAGDDEVTMLK
ARYHY

Sequences:

>Translated_85_residues
MRSVNFDPDAWEDFLFWLAADRKTARRITRLIGEIQRDPFSGIGKPEPLQGELSGYWSRRIDDEHRLVYRAGDDEVTMLK
ARYHY
>Mature_85_residues
MRSVNFDPDAWEDFLFWLAADRKTARRITRLIGEIQRDPFSGIGKPEPLQGELSGYWSRRIDDEHRLVYRAGDDEVTMLK
ARYHY

Specific function: Part of a toxin-antitoxin (TA) module. Has RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides

COG id: COG4115

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YoeB family

Homologues:

Organism=Escherichia coli, GI87082025, Length=77, Percent_Identity=49.3506493506493, Blast_Score=93, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YOEB_MYCBO (P64529)

Other databases:

- EMBL:   BX248345
- RefSeq:   NP_857034.1
- ProteinModelPortal:   P64529
- SMR:   P64529
- EnsemblBacteria:   EBMYCT00000016079
- GeneID:   1092121
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3393
- GeneTree:   EBGT00050000018557
- HOGENOM:   HBG664204
- OMA:   LAGFWSR
- ProtClustDB:   CLSK792442
- BioCyc:   MBOV233413:MB3393-MONOMER
- InterPro:   IPR009614
- TIGRFAMs:   TIGR02116

Pfam domain/function: PF06769 Plasmid_Txe

EC number: NA

Molecular weight: Translated: 10102; Mature: 10102

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: ACT_SITE 47-47 ACT_SITE 84-84

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSVNFDPDAWEDFLFWLAADRKTARRITRLIGEIQRDPFSGIGKPEPLQGELSGYWSRR
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCC
IDDEHRLVYRAGDDEVTMLKARYHY
CCCCCEEEEECCCCCEEEEEEECCC
>Mature Secondary Structure
MRSVNFDPDAWEDFLFWLAADRKTARRITRLIGEIQRDPFSGIGKPEPLQGELSGYWSRR
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCC
IDDEHRLVYRAGDDEVTMLKARYHY
CCCCCEEEEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972