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The map label for this gene is pmmB [C]

Identifier: 121639231

GI number: 121639231

Start: 3683435

End: 3685039

Strand: Direct

Name: pmmB [C]

Synonym: BCG_3373

Alternate gene names: 121639231

Gene position: 3683435-3685039 (Clockwise)

Preceding gene: 121639230

Following gene: 121639233

Centisome position: 84.2

GC content: 69.28

Gene sequence:

>1605_bases
GTGACGCCAGAGAATTGGATCGCCCACGACCCGGACCCGCAGACGGCCGCCGAGCTCGCCGCCTGCGGCCCCGACGAGCT
GAAAGCGCGGTTCAGCCGCCCACTGGCGTTCGGCACCGCGGGGTTGCGCGGGCACCTGCGGGGCGGGCCGGACGCGATGA
ACCTGGCGGTGGTGTTGCGCGCCACCTGGGCGGTGGCACGGGTGCTCACGGATCGAGGTCTGGCTGGTTCGCCGGTGATC
GTGGGGCGCGACGCTCGGCACGGCTCACCGGCGTTTGCCGCTGCGGCCGCCGAAGTGCTTGCCGCCGCAGGTTTTTCCGT
GCTGCTTCTGCCCGATCCCGCACCCACCCCGGTGGTGGCGTTCGCGGTGCGGCACACCGGCGCCGCCGCTGGGATACAGA
TCACGGCGTCACACAACCCGGCGACCGACAACGGCTACAAGGTCTATGTCGACGGCGGCCTTCAGCTCCTCGCCCCTACC
GACCGGCAGATCGAAGCCGCGATGGCCACCGCGCCCCCGGCCGATCAGATCGCCAGGAAGACCGTCAACCCCAGTGAAAA
CCGCGCCTCCGATCTGATCGACCGTTATATCCAGCGTGCGGCCGGGGTCCGAAGGTGCGCCGGTTCGGTCCGGGTGGCCC
TGACGCCGCTGCACGGGGTTGGCGGGGCGATGGCCGTCGAGACCCTTCGGCGAGCCGGTTTCACCGAGGTGCATACCGTG
GCGACGCAATTCGCGCCGAATCCCGACTTCCCCACCGTGACATTGCCGAACCCCGAGGAGCCCGGAGCCACCGACGCACT
GCTCACCCTGGCTACCGACGTGGACGCCGACGTCGCGATCGCGCTGGATCCCGATGCGGATCGCTGCGCGGTCGGGATAC
CCACGGTGTCGGGATGGCGGATGCTGTCCGGTGACGAAACCGGTTGGCTACTAGGTGATTACATCTTGTCGCAAACCGAC
GACCGGGCGTCGCCGCCGGAAACCAGGGTGGTGGCCAGCACCGTGGTGTCGTCGCGGATGCTGGCGGCGATCGCCGCGCA
TCACGCTGCCGTGCACGTGGAGACCCTCACCGGCTTTAAGTGGCTGGCGCGCGCCGATGCGAACCTGCCCGGCACCCTGG
TGTACGCCTACGAGGAAGCGATCGGGCACTGCGTCGACCCCACCGCGGTGCGTGACAAAGACGGCATCAGCGCCGCGGTG
TTGGTGTGCGATCTGGTGGCCGCGCTCAAAGGCCAGGGTCGTTCGGTGACCGACGCGCTCGACGAGCTCGCCCGATGCTA
CGGCGTGCATGAGGTTGCCGCCCTGTCACGCCCCGTGGGCGGCGCCGTCGAGACCACCGACCTGATGCGACGGCTCCGCG
AGGACCCGCCGCGTCGGCTGGCCGGTTTCCCCGCCACGGTCACCGATATCGGCGACACGCTGATCCTCACCGGCGGCGAC
GACAACATGTTGGTCAGGGTGGCGGTGCGGCCTTCTGGAACAGAACCGAAGCTGAAGTGCTACTTGGAGATTCGCTGCGC
GGTGACCGGTGACCTACCAGCTGCCCGACAGCTGGTGCGGGCGAGGATCGATGAGCTGTCGGCTAGCGTGCGGCGGTGGT
GGTGA

Upstream 100 bases:

>100_bases
CGGCGAGCCGCTGAGCCACGCCGAGGTGCTCGCCGCCGGAGCCGCATCGGCGACTCGGATGGGCGCGCTGCTAGCCGACG
TGATCGCCCGGTTCTAAGCC

Downstream 100 bases:

>100_bases
CTCAGCGCGGGCCGAACTGGCGATCGCCGGCATCGCCGAGACCGGGCACAATGTAGGCGACCTCGTTAAGCCCTTCGTCG
ATGGCCGCAGTGAACAACCG

Product: putative phosphomannomutase pmmB

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MTPENWIAHDPDPQTAAELAACGPDELKARFSRPLAFGTAGLRGHLRGGPDAMNLAVVLRATWAVARVLTDRGLAGSPVI
VGRDARHGSPAFAAAAAEVLAAAGFSVLLLPDPAPTPVVAFAVRHTGAAAGIQITASHNPATDNGYKVYVDGGLQLLAPT
DRQIEAAMATAPPADQIARKTVNPSENRASDLIDRYIQRAAGVRRCAGSVRVALTPLHGVGGAMAVETLRRAGFTEVHTV
ATQFAPNPDFPTVTLPNPEEPGATDALLTLATDVDADVAIALDPDADRCAVGIPTVSGWRMLSGDETGWLLGDYILSQTD
DRASPPETRVVASTVVSSRMLAAIAAHHAAVHVETLTGFKWLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAAV
LVCDLVAALKGQGRSVTDALDELARCYGVHEVAALSRPVGGAVETTDLMRRLREDPPRRLAGFPATVTDIGDTLILTGGD
DNMLVRVAVRPSGTEPKLKCYLEIRCAVTGDLPAARQLVRARIDELSASVRRWW

Sequences:

>Translated_534_residues
MTPENWIAHDPDPQTAAELAACGPDELKARFSRPLAFGTAGLRGHLRGGPDAMNLAVVLRATWAVARVLTDRGLAGSPVI
VGRDARHGSPAFAAAAAEVLAAAGFSVLLLPDPAPTPVVAFAVRHTGAAAGIQITASHNPATDNGYKVYVDGGLQLLAPT
DRQIEAAMATAPPADQIARKTVNPSENRASDLIDRYIQRAAGVRRCAGSVRVALTPLHGVGGAMAVETLRRAGFTEVHTV
ATQFAPNPDFPTVTLPNPEEPGATDALLTLATDVDADVAIALDPDADRCAVGIPTVSGWRMLSGDETGWLLGDYILSQTD
DRASPPETRVVASTVVSSRMLAAIAAHHAAVHVETLTGFKWLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAAV
LVCDLVAALKGQGRSVTDALDELARCYGVHEVAALSRPVGGAVETTDLMRRLREDPPRRLAGFPATVTDIGDTLILTGGD
DNMLVRVAVRPSGTEPKLKCYLEIRCAVTGDLPAARQLVRARIDELSASVRRWW
>Mature_533_residues
TPENWIAHDPDPQTAAELAACGPDELKARFSRPLAFGTAGLRGHLRGGPDAMNLAVVLRATWAVARVLTDRGLAGSPVIV
GRDARHGSPAFAAAAAEVLAAAGFSVLLLPDPAPTPVVAFAVRHTGAAAGIQITASHNPATDNGYKVYVDGGLQLLAPTD
RQIEAAMATAPPADQIARKTVNPSENRASDLIDRYIQRAAGVRRCAGSVRVALTPLHGVGGAMAVETLRRAGFTEVHTVA
TQFAPNPDFPTVTLPNPEEPGATDALLTLATDVDADVAIALDPDADRCAVGIPTVSGWRMLSGDETGWLLGDYILSQTDD
RASPPETRVVASTVVSSRMLAAIAAHHAAVHVETLTGFKWLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAAVL
VCDLVAALKGQGRSVTDALDELARCYGVHEVAALSRPVGGAVETTDLMRRLREDPPRRLAGFPATVTDIGDTLILTGGDD
NMLVRVAVRPSGTEPKLKCYLEIRCAVTGDLPAARQLVRARIDELSASVRRWW

Specific function: This Enzyme Participates In Both The Breakdown And Synthesis Of Glucose. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=570, Percent_Identity=32.8070175438597, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI31377548, Length=558, Percent_Identity=30.1075268817204, Blast_Score=201, Evalue=2e-51,
Organism=Escherichia coli, GI1788361, Length=234, Percent_Identity=29.0598290598291, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789566, Length=261, Percent_Identity=31.4176245210728, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71993870, Length=582, Percent_Identity=31.786941580756, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71993878, Length=307, Percent_Identity=33.8762214983713, Blast_Score=149, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6323934, Length=570, Percent_Identity=30.7017543859649, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI20129809, Length=558, Percent_Identity=30.8243727598566, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24651977, Length=456, Percent_Identity=32.2368421052632, Blast_Score=205, Evalue=6e-53,
Organism=Drosophila melanogaster, GI24653722, Length=462, Percent_Identity=30.952380952381, Blast_Score=188, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 56166; Mature: 56035

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPENWIAHDPDPQTAAELAACGPDELKARFSRPLAFGTAGLRGHLRGGPDAMNLAVVLR
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHH
ATWAVARVLTDRGLAGSPVIVGRDARHGSPAFAAAAAEVLAAAGFSVLLLPDPAPTPVVA
HHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEE
FAVRHTGAAAGIQITASHNPATDNGYKVYVDGGLQLLAPTDRQIEAAMATAPPADQIARK
EEEHHCCCCCCEEEEECCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHCCCCHHHHHHH
TVNPSENRASDLIDRYIQRAAGVRRCAGSVRVALTPLHGVGGAMAVETLRRAGFTEVHTV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHH
ATQFAPNPDFPTVTLPNPEEPGATDALLTLATDVDADVAIALDPDADRCAVGIPTVSGWR
HHHCCCCCCCCEEECCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCEEECCCCCCCCE
MLSGDETGWLLGDYILSQTDDRASPPETRVVASTVVSSRMLAAIAAHHAAVHVETLTGFK
EECCCCCCEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHCHH
WLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAAVLVCDLVAALKGQGRSVTDAL
HHHHCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
DELARCYGVHEVAALSRPVGGAVETTDLMRRLREDPPRRLAGFPATVTDIGDTLILTGGD
HHHHHHHCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHCCCCCCHHCCCCEEEEECCC
DNMLVRVAVRPSGTEPKLKCYLEIRCAVTGDLPAARQLVRARIDELSASVRRWW
CCEEEEEEECCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPENWIAHDPDPQTAAELAACGPDELKARFSRPLAFGTAGLRGHLRGGPDAMNLAVVLR
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHH
ATWAVARVLTDRGLAGSPVIVGRDARHGSPAFAAAAAEVLAAAGFSVLLLPDPAPTPVVA
HHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEE
FAVRHTGAAAGIQITASHNPATDNGYKVYVDGGLQLLAPTDRQIEAAMATAPPADQIARK
EEEHHCCCCCCEEEEECCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHCCCCHHHHHHH
TVNPSENRASDLIDRYIQRAAGVRRCAGSVRVALTPLHGVGGAMAVETLRRAGFTEVHTV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHH
ATQFAPNPDFPTVTLPNPEEPGATDALLTLATDVDADVAIALDPDADRCAVGIPTVSGWR
HHHCCCCCCCCEEECCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCEEECCCCCCCCE
MLSGDETGWLLGDYILSQTDDRASPPETRVVASTVVSSRMLAAIAAHHAAVHVETLTGFK
EECCCCCCEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHCHH
WLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAAVLVCDLVAALKGQGRSVTDAL
HHHHCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
DELARCYGVHEVAALSRPVGGAVETTDLMRRLREDPPRRLAGFPATVTDIGDTLILTGGD
HHHHHHHCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHCCCCCCHHCCCCEEEEECCC
DNMLVRVAVRPSGTEPKLKCYLEIRCAVTGDLPAARQLVRARIDELSASVRRWW
CCEEEEEEECCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]