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The map label for this gene is fbiA

Identifier: 121639150

GI number: 121639150

Start: 3593026

End: 3594021

Strand: Direct

Name: fbiA

Synonym: BCG_3290

Alternate gene names: 121639150

Gene position: 3593026-3594021 (Clockwise)

Preceding gene: 121639148

Following gene: 121639151

Centisome position: 82.14

GC content: 67.07

Gene sequence:

>996_bases
GTGAAGGTCACCGTTCTGGCCGGTGGAGTCGGCGGCGCCCGCTTCCTGCTCGGGGTCCAGCAGCTGCTCGGCCTGGGCCA
GTTTGCTGCCAATTCTGCCCACTCGGACGCCGACCACCAACTGAGCGCTGTCGTCAACGTCGGCGACGACGCCTGGATCC
ACGGGCTGCGTGTCTGCCCGGATCTGGACACCTGCATGTATACCCTGGGCGGCGGGGTGGACCCCCAGCGCGGCTGGGGC
CAGCGTGACGAAACTTGGCACGCCATGCAGGAACTGGTGCGCTATGGCGTGCAGCCCGACTGGTTCGAGCTCGGGGACCG
CGATCTGGCCACCCATCTGGTGCGCACCCAGATGCTGCAGGCCGGCTACCCCCTGTCACAGATCACCGAGGCCCTATGCG
ATCGCTGGCAACCGGGCGCCCGCTTGCTGCCTGCCACCGACGACCGTTGCGAAACCCATGTAGTGATCACCGACCCGGTC
GACGAAAGCCGCAAGGCGATCCATTTTCAGGAGTGGTGGGTGCGCTACCGTGCCCAGGTGCCGACGCACAGCTTTGCTTT
TGTCGGCGCTGAAAAGTCCAGCGCTGCAACCGAAGCGATCGCCGCCCTGGCCGACGCCGACATCATCATGCTGGCGCCGT
CTAATCCGGTGGTCAGCATCGGCGCCATCCTGGCCGTCCCCGGGATTCGCGCGGCGTTGCGGGAAGCAACCGCACCGATC
GTCGGCTACTCGCCGATCATCGGCGAAAAGCCGTTGCGCGGCATGGCCGATACGTGCCTTTCGGTTATCGGGGTGGATTC
CACCGCGGCCGCTGTGGGCCGGCACTACGGCGCGCGGTGCGCCACCGGGATACTGGACTGCTGGCTGGTGCACGACGGCG
ACCACGCTGAGATTGACGGGGTGACGGTGCGGTCGGTGCCGCTGCTGATGACCGACCCGAACGCGACGGCTGAGATGGTT
CGCGCCGGGTGCGACCTTGCGGGAGTGGTAGCTTGA

Upstream 100 bases:

>100_bases
ATAAAATTTCCGCGGTTCTGTTGTGGTTGGGTCCCGGCGTGTCGAGCGTGACTCGTAACCAACGTTTGGTGATGGGCGCC
GGGAGGTACTGTCCTGCGAT

Downstream 100 bases:

>100_bases
CCGGCCCCGAACATGGCTCCGCCTCGACCATCGAGATCCTGCCCGTCATCGGGCTGCCCGAATTCCGTCCCGGCGACGAT
CTGAGCGCCGCCGTCGCCGC

Product: LPPG:FO 2-phospho-L-lactate transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWG
QRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDDRCETHVVITDPV
DESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSSAATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPI
VGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGDHAEIDGVTVRSVPLLMTDPNATAEMV
RAGCDLAGVVA

Sequences:

>Translated_331_residues
MKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWG
QRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDDRCETHVVITDPV
DESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSSAATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPI
VGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGDHAEIDGVTVRSVPLLMTDPNATAEMV
RAGCDLAGVVA
>Mature_331_residues
MKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWG
QRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDDRCETHVVITDPV
DESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSSAATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPI
VGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGDHAEIDGVTVRSVPLLMTDPNATAEMV
RAGCDLAGVVA

Specific function: Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F42

COG id: COG0391

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COFD_MYCBO (Q7TWV4)

Other databases:

- EMBL:   BX248345
- RefSeq:   NP_856934.1
- ProteinModelPortal:   Q7TWV4
- EnsemblBacteria:   EBMYCT00000015128
- GeneID:   1093977
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3289
- GeneTree:   EBGT00050000017468
- HOGENOM:   HBG374278
- OMA:   SNPITSI
- ProtClustDB:   PRK13606
- BioCyc:   MBOV233413:MB3289-MONOMER
- HAMAP:   MF_01257
- InterPro:   IPR002882
- InterPro:   IPR010115
- TIGRFAMs:   TIGR01819

Pfam domain/function: PF01933 UPF0052

EC number: NA

Molecular weight: Translated: 35336; Mature: 35336

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCP
CEEEEEECCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCHHEEEEEECCCHHHHHHEECCC
DLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQ
CHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHH
AGYPLSQITEALCDRWQPGARLLPATDDRCETHVVITDPVDESRKAIHFQEWWVRYRAQV
CCCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC
PTHSFAFVGAEKSSAATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPI
CCCCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCEEHHHHHHCCHHHHHHHHHCCCC
VGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGDHAEIDG
CCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHEEEEEECCCCCEECC
VTVRSVPLLMTDPNATAEMVRAGCDLAGVVA
EEEEEEEEEEECCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCP
CEEEEEECCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCHHEEEEEECCCHHHHHHEECCC
DLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQ
CHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHH
AGYPLSQITEALCDRWQPGARLLPATDDRCETHVVITDPVDESRKAIHFQEWWVRYRAQV
CCCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC
PTHSFAFVGAEKSSAATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPI
CCCCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCEEHHHHHHCCHHHHHHHHHCCCC
VGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGDHAEIDG
CCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHEEEEEECCCCCEECC
VTVRSVPLLMTDPNATAEMVRAGCDLAGVVA
EEEEEEEEEEECCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972