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The map label for this gene is ucpA [H]

Identifier: 121639112

GI number: 121639112

Start: 3552333

End: 3553181

Strand: Direct

Name: ucpA [H]

Synonym: BCG_3252

Alternate gene names: 121639112

Gene position: 3552333-3553181 (Clockwise)

Preceding gene: 121639106

Following gene: 121639113

Centisome position: 81.21

GC content: 65.25

Gene sequence:

>849_bases
ATGTCACTCAACGGCAAGACCATGTTCATCTCTGGCGCCAGTCGCGGTATCGGCCTTGCGATCGCCAAGCGGGCCGCGCG
CGACGGCGCCAACATTGCCTTGATCGCCAAGACCGCCGAGCCGCATCCAAAGCTGCCAGGCACGGTGTTCACGGCCGCCA
AGGAACTCGAGGAAGCCGGCGGCCAGGCACTGCCGATCGTCGGGGATATCCGCGACCCGGATGCGGTCGCGTCCGCGGTG
GCCACCACCGTGGAGCAGTTCGGGGGCATCGATATCTGCGTCAACAATGCCTCGGCGATCAACTTAGGGTCCATCACCGA
GGTGCCAATGAAGCGTTTCGACCTGATGAACGGCATCCAGGTGCGTGGCACCTACGCAGTATCCCAAGCGTGCATTCCCC
ATATGAAAGGCCGTGAGAACCCGCACATCCTGACGCTGTCCCCGCCGATCCTGCTGGAGAAGAAGTGGCTGCGGCCGACG
GCCTACATGATGGCCAAGTACGGCATGACGCTGTGCGCGCTGGGAATCGCCGAGGAGATGCGCGCCGACGGCATCGCGTC
GAACACGTTGTGGCCACGCACGATGGTGGCCACCGCGGCGGTACAGAACCTGCTGGGCGGCGACGAGGCGATGGCGCGGT
CCCGCAAGCCCGAGGTATACGCCGACGCGGCCTACGTCATCGTCAACAAGCCCGCCACCGAATACACCGGCAAGACGCTG
CTGTGCGAGGACGTGCTCGTCGAATCCGGCGTCACCGACTTGTCGGTCTACGACTGCGTCCCAGGTGCGACGCTCGGCGT
CGACCTGTGGGTGGAAGACGCCAACCCGCCGGGGTACCTCCCGGCCTAG

Upstream 100 bases:

>100_bases
ACCAATCAACCGTGTTCGCCAGCGGGTTATTTCCAGCGCTGAATCGCATGCGGCCTGTCCCGCAGTCCGGTGGAATCGAG
CAGGGCGTTAGGGTGACGCC

Downstream 100 bases:

>100_bases
CGACAGCAAAACCCTGATCCTCGAGTTGCCCGACGAGCGGGCCGTCGCGATCGTGCCGGTGCCGTCGAAGTTGTCGCTGA
AGGCGGCCGGCGGCCCTAGG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPKLPGTVFTAAKELEEAGGQALPIVGDIRDPDAVASAV
ATTVEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHMKGRENPHILTLSPPILLEKKWLRPT
AYMMAKYGMTLCALGIAEEMRADGIASNTLWPRTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTL
LCEDVLVESGVTDLSVYDCVPGATLGVDLWVEDANPPGYLPA

Sequences:

>Translated_282_residues
MSLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPKLPGTVFTAAKELEEAGGQALPIVGDIRDPDAVASAV
ATTVEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHMKGRENPHILTLSPPILLEKKWLRPT
AYMMAKYGMTLCALGIAEEMRADGIASNTLWPRTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTL
LCEDVLVESGVTDLSVYDCVPGATLGVDLWVEDANPPGYLPA
>Mature_281_residues
SLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPKLPGTVFTAAKELEEAGGQALPIVGDIRDPDAVASAVA
TTVEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQVRGTYAVSQACIPHMKGRENPHILTLSPPILLEKKWLRPTA
YMMAKYGMTLCALGIAEEMRADGIASNTLWPRTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTLL
CEDVLVESGVTDLSVYDCVPGATLGVDLWVEDANPPGYLPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254986, Length=272, Percent_Identity=48.8970588235294, Blast_Score=265, Evalue=4e-71,
Organism=Homo sapiens, GI209862901, Length=251, Percent_Identity=26.6932270916335, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI19923983, Length=251, Percent_Identity=26.6932270916335, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87082100, Length=219, Percent_Identity=32.4200913242009, Blast_Score=91, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71982365, Length=268, Percent_Identity=50, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17558628, Length=268, Percent_Identity=51.1194029850746, Blast_Score=274, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17544670, Length=277, Percent_Identity=26.7148014440433, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=210, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357673, Length=278, Percent_Identity=52.158273381295, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI23397609, Length=202, Percent_Identity=31.6831683168317, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=27.6041666666667, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=24.8995983935743, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29815; Mature: 29684

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPKLPGTVFTAAKELEEAG
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
GQALPIVGDIRDPDAVASAVATTVEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQ
CCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCHHHHHHHHHHCCEE
VRGTYAVSQACIPHMKGRENPHILTLSPPILLEKKWLRPTAYMMAKYGMTLCALGIAEEM
EEEEHHHHHHHHHHCCCCCCCEEEEECCCCEECHHHCCHHHHHHHHHHHHHHHHHHHHHH
RADGIASNTLWPRTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTL
HHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEECEEEEEEECCCCCCCCCEE
LCEDVLVESGVTDLSVYDCVPGATLGVDLWVEDANPPGYLPA
EHHHHHHHCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPKLPGTVFTAAKELEEAG
CCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
GQALPIVGDIRDPDAVASAVATTVEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQ
CCEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCHHHHHHHHHHCCEE
VRGTYAVSQACIPHMKGRENPHILTLSPPILLEKKWLRPTAYMMAKYGMTLCALGIAEEM
EEEEHHHHHHHHHHCCCCCCCEEEEECCCCEECHHHCCHHHHHHHHHHHHHHHHHHHHHH
RADGIASNTLWPRTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTL
HHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEECEEEEEEECCCCCCCCCEE
LCEDVLVESGVTDLSVYDCVPGATLGVDLWVEDANPPGYLPA
EHHHHHHHCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]