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The map label for this gene is ctaE

Identifier: 121638074

GI number: 121638074

Start: 2435431

End: 2436042

Strand: Direct

Name: ctaE

Synonym: BCG_2209

Alternate gene names: 121638074

Gene position: 2435431-2436042 (Clockwise)

Preceding gene: 121638072

Following gene: 121638075

Centisome position: 55.67

GC content: 58.66

Gene sequence:

>612_bases
GTGACGAGTGCTGTTGGGACCTCGGGTACTGCCATCACATCGCGCGTGCATTCGCTGAATCGGCCCAACATGGTCAGTGT
CGGCACCATAGTGTGGCTATCCAGTGAATTAATGTTCTTTGCTGGGCTGTTCGCGTTCTATTTCTCGGCACGAGCTCAGG
CCGGCGGGAATTGGCCGCCGCCACCGACAGAACTGAATCTGTACCAGGCCGTCCCGGTCACGCTGGTCCTGATTGCCTCG
TCGTTCACCTGCCAGATGGGCGTGTTCGCGGCCGAACGCGGCGACATCTTCGGGCTGCGCCGCTGGTATGTGATCACATT
CCTGATGGGCCTGTTCTTCGTTCTGGGCCAGGCCTACGAGTATCGCAACCTGATGTCGCACGGGACGAGCATCCCCAGCA
GCGCATACGGCAGCGTGTTCTATCTGGCCACCGGATTCCATGGACTGCACGTCACCGGCGGCCTCATCGCCTTCATCTTC
CTGCTGGTACGCACTGGGATGAGCAAATTTACTCCGGCGCAGGCCACAGCCAGCATCGTCGTCTCTTACTACTGGCATTT
CGTCGACATCGTGTGGATCGCGCTATTCACCGTGATCTATTTCATCCGATGA

Upstream 100 bases:

>100_bases
ACTTGCGCTAACCAAACGGCCGGGCGACACGCGGAACTGACTTACCGAAATTTCCGACCCGGGTAGAGTTCGACAACTAC
AAAGCGTCATACTTGCGGAT

Downstream 100 bases:

>100_bases
GCCGGCGTCCGACGAACATCCCACGAACAGGAGTGCTCGGTTGACGAAACTGGGGTTCACCCGATCCGGTGGCAGTAAGA
GTGGTCGCACGCGACGGCGC

Product: putative cytochrome C oxidase (subunit III) ctaE

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MTSAVGTSGTAITSRVHSLNRPNMVSVGTIVWLSSELMFFAGLFAFYFSARAQAGGNWPPPPTELNLYQAVPVTLVLIAS
SFTCQMGVFAAERGDIFGLRRWYVITFLMGLFFVLGQAYEYRNLMSHGTSIPSSAYGSVFYLATGFHGLHVTGGLIAFIF
LLVRTGMSKFTPAQATASIVVSYYWHFVDIVWIALFTVIYFIR

Sequences:

>Translated_203_residues
MTSAVGTSGTAITSRVHSLNRPNMVSVGTIVWLSSELMFFAGLFAFYFSARAQAGGNWPPPPTELNLYQAVPVTLVLIAS
SFTCQMGVFAAERGDIFGLRRWYVITFLMGLFFVLGQAYEYRNLMSHGTSIPSSAYGSVFYLATGFHGLHVTGGLIAFIF
LLVRTGMSKFTPAQATASIVVSYYWHFVDIVWIALFTVIYFIR
>Mature_202_residues
TSAVGTSGTAITSRVHSLNRPNMVSVGTIVWLSSELMFFAGLFAFYFSARAQAGGNWPPPPTELNLYQAVPVTLVLIASS
FTCQMGVFAAERGDIFGLRRWYVITFLMGLFFVLGQAYEYRNLMSHGTSIPSSAYGSVFYLATGFHGLHVTGGLIAFIFL
LVRTGMSKFTPAQATASIVVSYYWHFVDIVWIALFTVIYFIR

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family

Homologues:

Organism=Homo sapiens, GI251831113, Length=152, Percent_Identity=37.5, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1786633, Length=177, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6226542, Length=202, Percent_Identity=30.1980198019802, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COX3_MYCBO (P63857)

Other databases:

- EMBL:   BX248341
- RefSeq:   NP_855865.1
- ProteinModelPortal:   P63857
- SMR:   P63857
- EnsemblBacteria:   EBMYCT00000015352
- GeneID:   1091330
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2216
- GeneTree:   EBGT00050000016542
- HOGENOM:   HBG565518
- OMA:   EYIHLVE
- ProtClustDB:   CLSK872023
- BioCyc:   MBOV233413:MB2216-MONOMER
- BRENDA:   1.9.3.1
- InterPro:   IPR000298
- InterPro:   IPR013833
- Gene3D:   G3DSA:1.20.120.80
- PANTHER:   PTHR11403

Pfam domain/function: PF00510 COX3; SSF81452 CytC_oxdse_III

EC number: =1.9.3.1

Molecular weight: Translated: 22420; Mature: 22289

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14183160)-; HASH(0x17177b20)-; HASH(0x16c63150)-; HASH(0x15e39b90)-; HASH(0x16aa1240)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAVGTSGTAITSRVHSLNRPNMVSVGTIVWLSSELMFFAGLFAFYFSARAQAGGNWPP
CCCCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PPTELNLYQAVPVTLVLIASSFTCQMGVFAAERGDIFGLRRWYVITFLMGLFFVLGQAYE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YRNLMSHGTSIPSSAYGSVFYLATGFHGLHVTGGLIAFIFLLVRTGMSKFTPAQATASIV
HHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VSYYWHFVDIVWIALFTVIYFIR
HHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TSAVGTSGTAITSRVHSLNRPNMVSVGTIVWLSSELMFFAGLFAFYFSARAQAGGNWPP
CCCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PPTELNLYQAVPVTLVLIASSFTCQMGVFAAERGDIFGLRRWYVITFLMGLFFVLGQAYE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YRNLMSHGTSIPSSAYGSVFYLATGFHGLHVTGGLIAFIFLLVRTGMSKFTPAQATASIV
HHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VSYYWHFVDIVWIALFTVIYFIR
HHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972