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The map label for this gene is ansP1

Identifier: 121638009

GI number: 121638009

Start: 2368626

End: 2370095

Strand: Direct

Name: ansP1

Synonym: BCG_2144

Alternate gene names: 121638009

Gene position: 2368626-2370095 (Clockwise)

Preceding gene: 121638007

Following gene: 121638010

Centisome position: 54.15

GC content: 61.97

Gene sequence:

>1470_bases
TTGAGCGCGGCCTCACAGCGTGTCGACGCCTTCGGCGAAGAGGCCGGCTATCACAAAGGCCTCAAGCCCCGACAACTGCA
GATGATCGGGATCGGCGGCGCGATTGGGACCGGCCTGTTCCTCGGCGCCAGCGGCCGGCTTGCCAAGGCCGGACCTGGGT
TGTTCTTGGTGTACGGCGTGTGCGGGGTTTTTGTCTTCCTGATCCTGCGGGCGCTGGGTGAGCTGGTGCTGCACCGTCCG
TCGTCAGGCTCGTTTGTGTCGTATGCACGTGAATTTTTCGGCGAGAAGGCCGCTTACGCGGTGGGCTGGATGTACTTCCT
GCACTGGGCGATGACGTCGATCGTGGACACCACCGCGATCGCCACCTACTTGCAGCGTTGGACGATCTTCACGGTGGTCC
CGCAATGGATTCTTGCCCTGATCGCCTTGACGGTGGTGTTGTCGATGAACCTGATTTCGGTCGAATGGTTCGGCGAGCTG
GAGTTTTGGGCCGCGCTGATCAAGGTTCTCGCGCTGATGGCGTTCCTAGTGGTGGGAACCGTTTTTTTGGCCGGGCGATA
CCCCGTCGACGGCCACAGCACCGGATTGAGCTTGTGGAACAACCATGGCGGGCTGTTCCCGACAAGCTGGCTGCCGCTGC
TGATCGTTACCTCGGGAGTGGTGTTCGCGTACTCAGCAGTCGAATTGGTAGGGACGGCGGCCGGGGAGACCGCCGAGCCG
GAGAAGATCATGCCGCGGGCGATCAATTCGGTGGTCGCTCGCATCGCGATCTTTTATGTCGGGTCGGTGGCCCTGCTAGC
GCTGTTGCTGCCGTATACCGCCTACAAGGCCGGCGAGAGCCCGTTCGTCACGTTCTTTTCCAAAATCGGTTTCCACGGTG
CCGGTGACTTGATGAACATCGTTGTGCTTACCGCCGCGCTGTCGAGCCTGAACGCGGGGCTGTATTCGACCGGCCGCGTC
ATGCATTCGATCGCGATGAGCGGCAGCGCCCCAAGGTTCACCGCGCGAATGTCGAAAAGCGGTGTGCCCTACGGCGGGAT
CGTGTTGACCGCGGTCATCACCCTGTTCGGTGTCGCGCTGAACGCCTTCAAGCCCGGTGAAGCCTTCGAGATTGTGCTCA
ACATGTCCGCGCTGGGCATCATCGCGGGTTGGGCCACCATCGTGCTGTGTCAGCTTCGACTTCACAAGCTGGCCAACGCC
GGGATCATGCAGCGGCCGCGGTTCCGCATGCCCTTCTCCCCCTACAGCGGCTACCTCACCTTGCTCTTCTTGCTTGTCGT
GCTGGTTACGATGGCGTCCGACAAACCGATCGGCACCTGGACGGTGGCGACACTGATTATTGTCATTCCGGCCCTGACCG
CAGGCTGGTACCTGGTACGCAAGCGTGTCATGGCCGTCGCCCGCGAAAGGCTGGGTCATACCGGGCCATTTCCGGCGGTC
GCCAACCCGCCCGTGAGGTCAAGAGACTGA

Upstream 100 bases:

>100_bases
TTGCCGCCACCCCTAGAGTGGGCGAGGATCGCAAGAGCAAATTCCGCGCCGGTAGGACAACGATAGGACCGCCATTACGA
AGCCGCCCGAGACTCCTGAA

Downstream 100 bases:

>100_bases
TGCTTCGAAGAGGTGAATCGATCATCCGCAACCGTTACGCCAGTAAGCCACCACTGTACGGAATGGCAATGGTCTTCTTG
GCCATGGCCGTCGTCGCCGT

Product: putative L-asparagine permease ansP1

Products: Proton [Cytoplasm]; L-asparagine [Cytoplasm] [C]

Alternate protein names: L-asparagine transport protein 1

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSAASQRVDAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGASGRLAKAGPGLFLVYGVCGVFVFLILRALGELVLHRP
SSGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVPQWILALIALTVVLSMNLISVEWFGEL
EFWAALIKVLALMAFLVVGTVFLAGRYPVDGHSTGLSLWNNHGGLFPTSWLPLLIVTSGVVFAYSAVELVGTAAGETAEP
EKIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNAGLYSTGRV
MHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANA
GIMQRPRFRMPFSPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAV
ANPPVRSRD

Sequences:

>Translated_489_residues
MSAASQRVDAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGASGRLAKAGPGLFLVYGVCGVFVFLILRALGELVLHRP
SSGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVPQWILALIALTVVLSMNLISVEWFGEL
EFWAALIKVLALMAFLVVGTVFLAGRYPVDGHSTGLSLWNNHGGLFPTSWLPLLIVTSGVVFAYSAVELVGTAAGETAEP
EKIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNAGLYSTGRV
MHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANA
GIMQRPRFRMPFSPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAV
ANPPVRSRD
>Mature_488_residues
SAASQRVDAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGASGRLAKAGPGLFLVYGVCGVFVFLILRALGELVLHRPS
SGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAIATYLQRWTIFTVVPQWILALIALTVVLSMNLISVEWFGELE
FWAALIKVLALMAFLVVGTVFLAGRYPVDGHSTGLSLWNNHGGLFPTSWLPLLIVTSGVVFAYSAVELVGTAAGETAEPE
KIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGESPFVTFFSKIGFHGAGDLMNIVVLTAALSSLNAGLYSTGRVM
HSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVALNAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAG
IMQRPRFRMPFSPYSGYLTLLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAVA
NPPVRSRD

Specific function: Unknown

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family

Homologues:

Organism=Homo sapiens, GI181337167, Length=342, Percent_Identity=24.8538011695906, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI87081915, Length=463, Percent_Identity=60.0431965442765, Blast_Score=533, Evalue=1e-152,
Organism=Escherichia coli, GI1786302, Length=425, Percent_Identity=36.7058823529412, Blast_Score=281, Evalue=7e-77,
Organism=Escherichia coli, GI1786789, Length=425, Percent_Identity=36.2352941176471, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1790653, Length=471, Percent_Identity=34.6072186836518, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI48994972, Length=420, Percent_Identity=37.6190476190476, Blast_Score=271, Evalue=9e-74,
Organism=Escherichia coli, GI1786602, Length=456, Percent_Identity=33.7719298245614, Blast_Score=259, Evalue=4e-70,
Organism=Escherichia coli, GI87081708, Length=426, Percent_Identity=33.3333333333333, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1788480, Length=434, Percent_Identity=33.6405529953917, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789017, Length=425, Percent_Identity=32.4705882352941, Blast_Score=225, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6324061, Length=448, Percent_Identity=32.1428571428571, Blast_Score=223, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6320772, Length=442, Percent_Identity=31.2217194570136, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324059, Length=453, Percent_Identity=31.3465783664459, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6322892, Length=424, Percent_Identity=31.1320754716981, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324990, Length=443, Percent_Identity=27.9909706546275, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324924, Length=452, Percent_Identity=27.8761061946903, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6324553, Length=448, Percent_Identity=28.5714285714286, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321053, Length=426, Percent_Identity=26.9953051643192, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6320717, Length=398, Percent_Identity=26.3819095477387, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6321629, Length=419, Percent_Identity=27.4463007159904, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322967, Length=440, Percent_Identity=27.0454545454545, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319824, Length=414, Percent_Identity=24.8792270531401, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6324981, Length=391, Percent_Identity=29.156010230179, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6320251, Length=418, Percent_Identity=23.6842105263158, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319543, Length=395, Percent_Identity=26.3291139240506, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319608, Length=442, Percent_Identity=25.3393665158371, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319542, Length=407, Percent_Identity=24.0786240786241, Blast_Score=113, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320364, Length=486, Percent_Identity=23.4567901234568, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANSP1_MYCBO (Q7VEQ4)

Other databases:

- EMBL:   BX248341
- RefSeq:   NP_855800.1
- EnsemblBacteria:   EBMYCT00000017839
- GeneID:   1091204
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2151
- GeneTree:   EBGT00050000015723
- HOGENOM:   HBG492579
- OMA:   FIVVCQM
- ProtClustDB:   CLSK799376
- BioCyc:   MBOV233413:MB2151-MONOMER
- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840
- PANTHER:   PTHR11785
- PIRSF:   PIRSF006060

Pfam domain/function: PF00324 AA_permease

EC number: NA

Molecular weight: Translated: 52536; Mature: 52405

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x161903b8)-; HASH(0x16e48148)-; HASH(0x164c7088)-; HASH(0x16e50124)-; HASH(0x1652f504)-; HASH(0x1519a378)-; HASH(0x12a8bb18)-; HASH(0x169838e8)-; HASH(0x163c8f80)-; HASH(0x16586880)-; HASH(0x16b0b220)-; HASH(0x12386db0)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAASQRVDAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGASGRLAKAGPGLFLVYGV
CCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHHHH
CGVFVFLILRALGELVLHRPSSGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATYLQRWTIFTVVPQWILALIALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLVVGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHH
VFLAGRYPVDGHSTGLSLWNNHGGLFPTSWLPLLIVTSGVVFAYSAVELVGTAAGETAEP
HHHHCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EKIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGESPFVTFFSKIGFHGAGDLMNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHH
VVLTAALSSLNAGLYSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVAL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
NAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRMPFSPYSGYLT
HCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
LLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ANPPVRSRD
CCCCCCCCH
>Mature Secondary Structure 
SAASQRVDAFGEEAGYHKGLKPRQLQMIGIGGAIGTGLFLGASGRLAKAGPGLFLVYGV
CCHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHHHH
CGVFVFLILRALGELVLHRPSSGSFVSYAREFFGEKAAYAVGWMYFLHWAMTSIVDTTAI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATYLQRWTIFTVVPQWILALIALTVVLSMNLISVEWFGELEFWAALIKVLALMAFLVVGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHH
VFLAGRYPVDGHSTGLSLWNNHGGLFPTSWLPLLIVTSGVVFAYSAVELVGTAAGETAEP
HHHHCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EKIMPRAINSVVARIAIFYVGSVALLALLLPYTAYKAGESPFVTFFSKIGFHGAGDLMNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHH
VVLTAALSSLNAGLYSTGRVMHSIAMSGSAPRFTARMSKSGVPYGGIVLTAVITLFGVAL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
NAFKPGEAFEIVLNMSALGIIAGWATIVLCQLRLHKLANAGIMQRPRFRMPFSPYSGYLT
HCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
LLFLLVVLVTMASDKPIGTWTVATLIIVIPALTAGWYLVRKRVMAVARERLGHTGPFPAV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ANPPVRSRD
CCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-asparagine [Periplasm]; Proton [Periplasm] [C]

Specific reaction: L-asparagine [Periplasm] + Proton [Periplasm] = Proton [Cytoplasm] + L-asparagine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972