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The map label for this gene is prcA [H]

Identifier: 121637991

GI number: 121637991

Start: 2349077

End: 2349823

Strand: Reverse

Name: prcA [H]

Synonym: BCG_2126c

Alternate gene names: 121637991

Gene position: 2349823-2349077 (Counterclockwise)

Preceding gene: 121637992

Following gene: 121637988

Centisome position: 53.72

GC content: 63.45

Gene sequence:

>747_bases
GTGAGTTTTCCGTATTTCATCTCGCCTGAGCAGGCGATGCGCGAGCGCAGCGAGTTGGCGCGTAAGGGCATTGCGCGGGC
CAAAAGCGTGGTGGCGCTGGCCTATGCCGGTGGTGTGCTGTTCGTCGCGGAGAATCCGTCGCGGTCGCTGCAGAAGATCA
GTGAGCTCTACGATCGGGTGGGTTTTGCGGCTGCGGGCAAGTTCAACGAGTTCGACAATTTGCGCCGCGGCGGGATCCAG
TTCGCCGACACCCGCGGTTACGCCTATGACCGTCGTGACGTCACGGGTCGGCAGTTGGCCAATGTCTACGCGCAGACTCT
AGGCACCATCTTCACCGAACAGGCCAAGCCCTACGAGGTTGAGTTGTGTGTGGCCGAGGTGGCGCATTACGGCGAGACGA
AACCCCCTGAGTTGTATCGTATTACCTACGACGGGTCGATCGCCGACGAGCCGCATTTCGTGGTGATGGGCGGCACCACG
GAGCCGATCGCCAACGCGCTCAAAGAGTCGTATGCCGAGAACGCCAGCCTGACCGACGCCCTGGGTATCGCGGTCGCTGC
ATTGCGGGCCGGCAGTGCCGACACCTCGGGTGGTGATCAACCCACCCTTGGCGTGGCCAGCTTAGAGGTGGCCGTTCTCG
ATGCCAACCGGCCACGGCGCGCGTTCCGGCGCATCACCGGCTCCGCCCTGCAAGCGTTGCTGGTAGACCAGGAAAGCCCG
CAGTCTGACGGCGAATCGTCGGGCTGA

Upstream 100 bases:

>100_bases
GGGCGGTTGACGTGCCGGAGAGCCGGATTGCCGAATTGGCCCGCGCGATCATCGAAAGCCGTTCGGGTGCGGATACTTTC
GGCTCCGATGGCGGTGAGAA

Downstream 100 bases:

>100_bases
GTCCGAAAGTCCGACGCGTGTCTGGGACCCCGCTGCGACGTTAACTGCGCCTAACCCCGGCTCGACGCGTCGCCGGCCGT
CCTGACTTTTGTCACTGCGG

Product: proteasome subunit alpha PrcA

Products: NA

Alternate protein names: 20S proteasome alpha subunit; Proteasome core protein PrcA [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQ
FADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADEPHFVVMGGTT
EPIANALKESYAENASLTDALGIAVAALRAGSADTSGGDQPTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQESP
QSDGESSG

Sequences:

>Translated_248_residues
MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQ
FADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADEPHFVVMGGTT
EPIANALKESYAENASLTDALGIAVAALRAGSADTSGGDQPTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQESP
QSDGESSG
>Mature_247_residues
SFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQF
ADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADEPHFVVMGGTTE
PIANALKESYAENASLTDALGIAVAALRAGSADTSGGDQPTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQESPQ
SDGESSG

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation [H]

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022296
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: =3.4.25.1 [H]

Molecular weight: Translated: 26723; Mature: 26592

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRV
CCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEECCCHHHHHHHHHHHHHH
GFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEV
CHHHCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEH
ELCVAEVAHYGETKPPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHH
LGIAVAALRAGSADTSGGDQPTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQESP
HHHHHHHHHCCCCCCCCCCCCCEEHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
QSDGESSG
CCCCCCCC
>Mature Secondary Structure 
SFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRV
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEECCCHHHHHHHHHHHHHH
GFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEV
CHHHCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEH
ELCVAEVAHYGETKPPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHH
LGIAVAALRAGSADTSGGDQPTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQESP
HHHHHHHHHCCCCCCCCCCCCCEEHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
QSDGESSG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA