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The map label for this gene is PPE36

Identifier: 121637990

GI number: 121637990

Start: 2347806

End: 2348537

Strand: Direct

Name: PPE36

Synonym: BCG_2125

Alternate gene names: 121637990

Gene position: 2347806-2348537 (Clockwise)

Preceding gene: 121637989

Following gene: 121637995

Centisome position: 53.67

GC content: 58.61

Gene sequence:

>732_bases
ATGCCCAATTTCTGGGCGTTGCCGCCCGAGATCAACTCCACCCGGATATATCTCGGCCCGGGTTCTGGCCCGATACTGGC
CGCCGCCCAGGGATGGAACGCTCTGGCCAGTGAGCTGGAAAAGACGAAGGTGGGGTTGCAGTCAGCGCTCGACACGTTGC
TGGAGTCGTATAGGGGTCAGTCGTCGCAGGCTTTGATACAGCAGACCTTGCCGTATGTGCAGTGGCTGACCACGACCGCC
GAGCACGCCCATAAGACCGCGATCCAGCTCACGGCAGCGGCGAACGCCTACGAGCAGGCTAGAGCGGCGATGGTGCCGCC
GGCGATGGTGCGCGCGAACCGCGTGCAGACCACAGTGTTGAAGGCAATCAACTGGTTCGGGCAATTCTCCACCAGGATCG
CCGACAAGGAGGCCGACTACGAACAGATGTGGTTCCAAGACGCGCTAGTGATGGAGAACTATTGGGAAGCCGTGCAAGAG
GCGATACAGTCGACGTCGCATTTTGAGGATCCACCGGAGATGGCCGACGACTACGACGAGGCCTGGATGCTCAACACCGT
GTTCGACTATCACAACGAGAACGCAAAAGAGGAGGTCATCCATCTCGTGCCCGACGTGAACAAGGAGAGGGGGCCCATCG
AACTCGTAACCAAGGTAGACAAAGAGGGGACCATCAGACTCGTCTACGATGGGGAGCCCACGTTTTCATACAAGGAACAT
CCTAAGTTTTGA

Upstream 100 bases:

>100_bases
CTTGCGTATGAGGAAGTCGAGATCGCCAACAACGAAGGTTTCTAACGTGTCGCCAGTTACGCACGAGTGGCTACCAGCGA
GTACAAGGGAGTAACGAATT

Downstream 100 bases:

>100_bases
TTCGGGAACATCCTAAGAAACGGGGGGCGTCGCCGTTGGAGACGTCGCAACGTGTCCGCAGTCCCAAGGGCAACAGTGAA
GGGCCCACGGTGCGATCCCC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MPNFWALPPEINSTRIYLGPGSGPILAAAQGWNALASELEKTKVGLQSALDTLLESYRGQSSQALIQQTLPYVQWLTTTA
EHAHKTAIQLTAAANAYEQARAAMVPPAMVRANRVQTTVLKAINWFGQFSTRIADKEADYEQMWFQDALVMENYWEAVQE
AIQSTSHFEDPPEMADDYDEAWMLNTVFDYHNENAKEEVIHLVPDVNKERGPIELVTKVDKEGTIRLVYDGEPTFSYKEH
PKF

Sequences:

>Translated_243_residues
MPNFWALPPEINSTRIYLGPGSGPILAAAQGWNALASELEKTKVGLQSALDTLLESYRGQSSQALIQQTLPYVQWLTTTA
EHAHKTAIQLTAAANAYEQARAAMVPPAMVRANRVQTTVLKAINWFGQFSTRIADKEADYEQMWFQDALVMENYWEAVQE
AIQSTSHFEDPPEMADDYDEAWMLNTVFDYHNENAKEEVIHLVPDVNKERGPIELVTKVDKEGTIRLVYDGEPTFSYKEH
PKF
>Mature_242_residues
PNFWALPPEINSTRIYLGPGSGPILAAAQGWNALASELEKTKVGLQSALDTLLESYRGQSSQALIQQTLPYVQWLTTTAE
HAHKTAIQLTAAANAYEQARAAMVPPAMVRANRVQTTVLKAINWFGQFSTRIADKEADYEQMWFQDALVMENYWEAVQEA
IQSTSHFEDPPEMADDYDEAWMLNTVFDYHNENAKEEVIHLVPDVNKERGPIELVTKVDKEGTIRLVYDGEPTFSYKEHP
KF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE36_MYCTU (P95315)

Other databases:

- EMBL:   U88049
- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   G70511
- RefSeq:   NP_336636.1
- RefSeq:   YP_177859.1
- HSSP:   Q79FE1
- ProteinModelPortal:   P95315
- SMR:   P95315
- EnsemblBacteria:   EBMYCT00000001693
- EnsemblBacteria:   EBMYCT00000070009
- GeneID:   887814
- GeneID:   924542
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2167
- KEGG:   mtu:Rv2108
- TIGR:   MT2167
- TubercuList:   Rv2108
- GeneTree:   EBGT00050000014888
- HOGENOM:   HBG571146
- ProtClustDB:   CLSK799875
- InterPro:   IPR000030

Pfam domain/function: PF00823 PPE

EC number: NA

Molecular weight: Translated: 27480; Mature: 27349

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNFWALPPEINSTRIYLGPGSGPILAAAQGWNALASELEKTKVGLQSALDTLLESYRGQ
CCCCCCCCCCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SSQALIQQTLPYVQWLTTTAEHAHKTAIQLTAAANAYEQARAAMVPPAMVRANRVQTTVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KAINWFGQFSTRIADKEADYEQMWFQDALVMENYWEAVQEAIQSTSHFEDPPEMADDYDE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHH
AWMLNTVFDYHNENAKEEVIHLVPDVNKERGPIELVTKVDKEGTIRLVYDGEPTFSYKEH
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHEECCCCCCEEEEECCCCCCCCCCC
PKF
CCC
>Mature Secondary Structure 
PNFWALPPEINSTRIYLGPGSGPILAAAQGWNALASELEKTKVGLQSALDTLLESYRGQ
CCCCCCCCCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SSQALIQQTLPYVQWLTTTAEHAHKTAIQLTAAANAYEQARAAMVPPAMVRANRVQTTVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KAINWFGQFSTRIADKEADYEQMWFQDALVMENYWEAVQEAIQSTSHFEDPPEMADDYDE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHH
AWMLNTVFDYHNENAKEEVIHLVPDVNKERGPIELVTKVDKEGTIRLVYDGEPTFSYKEH
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHEECCCCCCEEEEECCCCCCCCCCC
PKF
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10970728; 9634230; 12218036